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Index > Protein center > Icam1(Gene name) > Mouse
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  • Icam1 (Gene name),
  • Intercellular adhesion molecule 1 (Protein name ),  ICAM1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Icam1(Icam-1);
    Protein name:
    Intercellular adhesion molecule 1(ICAM-1);
    Alternative:
    MALA-2;MyD10;
    CD:
    CD54;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF.
    Function:
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    537
    Sequence:
    50:
    MASTRAKPTL | PLLLALVTVV | IPGPGDAQVS | IHPREAFLPQ | GGSVQVNCSS | 
    100:
    SCKEDLSLGL | ETQWLKDELE | SGPNWKLFEL | SEIGEDSSPL | CFENCGTVQS | 
    150:
    SASATITVYS | FPESVELRPL | PAWQQVGKDL | TLRCHVDGGA | PRTQLSAVLL | 
    200:
    RGEEILSRQP | VGGHPKDPKE | ITFTVLASRG | DHGANFSCRT | ELDLRPQGLA | 
    250:
    LFSNVSEARS | LRTFDLPATI | PKLDTPDLLE | VGTQQKLFCS | LEGLFPASEA | 
    300:
    RIYLELGGQM | PTQESTNSSD | SVSATALVEV | TEEFDRTLPL | RCVLELADQI | 
    350:
    LETQRTLTVY | NFSAPVLTLS | QLEVSEGSQV | TVKCEAHSGS | KVVLLSGVEP | 
    400:
    RPPTPQVQFT | LNASSEDHKR | SFFCSAALEV | AGKFLFKNQT | LELHVLYGPR | 
    450:
    LDETDCLGNW | TWQEGSQQTL | KCQAWGNPSP | KMTCRRKADG | ALLPIGVVKS | 
    500:
    VKQEMNGTYV | CHAFSSHGNV | TRNVYLTVLY | HSQNNWTIII | LVPVLLVIVG | 
    537:
    LVMAASYVYN | RQRKIRIYKL | QKAQEEAIKL | KGQAPPP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ICAM-1
    Cat.:
    E0048r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse ICAM-1
    Cat.:
    E0048m
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse ICAM-1
    Cat.:
    E0048d
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    ELISA Kit for Mouse ICAM-1
    Cat.:
    E0048h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ICAM-1
    Cat.:
    E0048b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ICAM-1
    Cat.:
    U0048b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ICAM-1
    Cat.:
    U0048h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse ICAM-1
    Cat.:
    U0048d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse ICAM-1
    Cat.:
    U0048m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse ICAM-1
    Cat.:
    U0048r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse ICAM-1
    Polyclonal Antibody for Mouse ICAM-1
    Cat.:
    P0048Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ICAM-1
    Polyclonal Antibody for Mouse ICAM-1
    Cat.:
    P0048Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ICAM-1
    Cat.:
    P0048Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse ICAM-1
    Monoclonal Antibody for Mouse ICAM-1
    Monoclonal Antibody for Mouse ICAM-1
    Monoclonal Antibody for Mouse ICAM-1
    Monoclonal Antibody for Mouse ICAM-1
    Protein for Mouse ICAM-1
    Protein for Mouse ICAM-1
    Protein for Mouse ICAM-1
    Protein for Mouse ICAM-1
    Protein for Mouse ICAM-1

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning of murine intercellular adhesion molecule (ICAM-1)."
      Horley K.J. , Carpenito C. , Baker B. , Takei F.
      EMBO J.8:2889-2896(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      strain: BALB/c.
      tissue: Myeloma.
    2. 2.
      Takei F.
      Submitted (1990-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "Isolation of the murine intercellular adhesion molecule 1 (ICAM-1) gene. ICAM-1 enhances antigen-specific T cell activation."
      Siu G. , Hedrick S.M. , Brian A.A.
      J. Immunol.143:3813-3820(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Nucleotide sequence of the cDNA for murine intercellular adhesion molecule-1 (ICAM-1)."
      Ballantyne C.M. , O'Brien W.E. , Beaudet A.L.
      Nucleic Acids Res.17:5853-5853(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6 X CBA.
      tissue: Thymus.
    5. 5.
      "Characterization of the murine Icam-1 gene."
      Ballantyne C.M. , Sligh J.E. , Dai X.Y. , Beaudet A.L.
      Genomics14:1076-1080(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: NIH Swiss.
    6. 6.
      "Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variants."
      Lord K.A. , Hoffman-Liebermann B. , Liebermann D.A.
      Oncogene5:387-396(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-131
    7. 7.
      "N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry."
      Otto V.I. , Damoc E. , Cueni L.N. , Schurpf T. , Frei R. , Ali S. , Callewaert N. , Moise A. , Leary J.A. , Folkers G. , Przybylski M.
      Glycobiology16:1033-1044(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-47; ASN-185; ASN-204; ASN-267; ASN-311; ASN-362; ASN-388; ASN-409 AND ASN-456;ABSENCE OF GLYCOSYLATION AT ASN-469 AND ASN-485;IDENTIFICATION BY MASS SPECTROMETRY
    8. 8.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-185; ASN-204; ASN-362; ASN-388; ASN-409 AND ASN-469
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