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Index > Protein center > CNDP2(Gene name) > Human
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  • CNDP2 (Gene name),
  • Cytosolic non-specific dipeptidase (Protein name ),  CNDP2_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    CNDP2(CN2;CPGL;PEPA);
    Protein name:
    Cytosolic non-specific dipeptidase;
    Alternative:
    Glutamate carboxypeptidase-like protein 1;CNDP dipeptidase 2;Peptidase A;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    475
    Sequence:
    50:
    MAALTTLFKY | IDENQDRYIK | KLAKWVAIQS | VSAWPEKRGE | IRRMMEVAAA | 
    100:
    DVKQLGGSVE | LVDIGKQKLP | DGSEIPLPPI | LLGRLGSDPQ | KKTVCIYGHL | 
    150:
    DVQPAALEDG | WDSEPFTLVE | RDGKLYGRGS | TDDKGPVAGW | INALEAYQKT | 
    200:
    GQEIPVNVRF | CLEGMEESGS | EGLDELIFAR | KDTFFKDVDY | VCISDNYWLG | 
    250:
    KKKPCITYGL | RGICYFFIEV | ECSNKDLHSG | VYGGSVHEAM | TDLILLMGSL | 
    300:
    VDKRGNILIP | GINEAVAAVT | EEEHKLYDDI | DFDIEEFAKD | VGAQILLHSH | 
    350:
    KKDILMHRWR | YPSLSLHGIE | GAFSGSGAKT | VIPRKVVGKF | SIRLVPNMTP | 
    400:
    EVVGEQVTSY | LTKKFAELRS | PNEFKVYMGH | GGKPWVSDFS | HPHYLAGRRA | 
    450:
    MKTVFGVEPD | LTREGGSIPV | TLTFQEATGK | NVMLLPVGSA | DDGAHSQNEK | 
    475:
    LNRYNYIEGT | KMLAAYLYEV | SQLKD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cytosolic non-specific dipeptidase
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    E1189h
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    ELISA Kit for Human Cytosolic non-specific dipeptidase
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    E1189m
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    96T
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    ELISA Kit for Human Cytosolic non-specific dipeptidase
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    E1189r
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    Packing:
    96T
    ELISA Kit for Human Cytosolic non-specific dipeptidase
    Cat.:
    E1189b
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    Packing:
    96T
    CLIA Kit for Human Cytosolic non-specific dipeptidase
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    U1189r
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    Packing:
    96T
    CLIA Kit for Human Cytosolic non-specific dipeptidase
    Cat.:
    U1189b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cytosolic non-specific dipeptidase
    Cat.:
    U1189h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Cytosolic non-specific dipeptidase
    Cat.:
    U1189m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cytosolic non-specific dipeptidase
    Cat.:
    P1189Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cytosolic non-specific dipeptidase
    Polyclonal Antibody for Human Cytosolic non-specific dipeptidase
    Cat.:
    P1189Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cytosolic non-specific dipeptidase
    Cat.:
    P1189Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Cytosolic non-specific dipeptidase
    Monoclonal Antibody for Human Cytosolic non-specific dipeptidase
    Monoclonal Antibody for Human Cytosolic non-specific dipeptidase
    Monoclonal Antibody for Human Cytosolic non-specific dipeptidase
    Protein for Human Cytosolic non-specific dipeptidase
    Protein for Human Cytosolic non-specific dipeptidase
    Protein for Human Cytosolic non-specific dipeptidase
    Protein for Human Cytosolic non-specific dipeptidase

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    Precision
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    Linearity
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    References
    1. 1.
      "Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase."
      Teufel M. , Saudek V. , Ledig J.P. , Bernhardt A. , Boularand S. , Carreau A. , Cairns N.J. , Carter C. , Cowley D.J. , Duverger D. , Ganzhorn A.J. , Guenet C. , Heintzelmann B. , Laucher V. , Sauvage C. , Smirnova T.
      J. Biol. Chem.278:6521-6531(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 129-137; 276-289; 311-329; 370-375 AND 462-474;CATALYTIC ACTIVITY;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES;SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Brain.
    2. 2.
      "Cloning and sequencing of human glutamate carboxypeptidase homologue in peptidase family M20."
      Chen J.M. , Barrett A.J.
      Submitted (2001-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT HIS-126
      tissue: Uterus.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Spleen.
      tissue: Teratocarcinoma.
    4. 4.
      "Large-scale cDNA transfection screening for genes related to cancer development and progression."
      Wan D. , Gong Y. , Qin W. , Zhang P. , Li J. , Wei L. , Zhou X. , Li H. , Qiu X. , Zhong F. , He L. , Yu J. , Yao G. , Jiang H. , Qian L. , Yu Y. , Shu H. , Chen X. , more...
      Proc. Natl. Acad. Sci. U.S.A.101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Colon.
      tissue: Kidney.
    7. 8.
      Bienvenut W.V. , Heiserich L. , Gottlieb E.
      Submitted (2008-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-9; 54-66; 255-275 AND 403-430;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Colon carcinoma.
    8. 9.
      "Identification of carboxypeptidase of glutamate like-B as a candidate suppressor in cell growth and metastasis in human hepatocellular carcinoma."
      Zhang P. , Chan D.W. , Zhu Y. , Li J.J. , Ng I.-O. , Wan D. , Gu J.
      Clin. Cancer Res.12:6617-6625(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;FUNCTION
    9. 10.
      "Dug1p Is a Cys-Gly peptidase of the gamma-glutamyl cycle of Saccharomyces cerevisiae and represents a novel family of Cys-Gly peptidases."
      Kaur H. , Kumar C. , Junot C. , Toledano M.B. , Bachhawat A.K.
      J. Biol. Chem.284:14493-14502(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES
    10. 11.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2 AND LYS-9;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 13.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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