C3 ELISA Kit for Mouse(Mus musculus) | EIAab.comC3 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > C3(Gene name) > Mouse

C3 (Gene name),

Complement C3 (Protein name ), CO3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

C3;

Protein name:

Complement C3;

Alternative:

HSE-MSF;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

C3dg interacts with CR2 (via the N-terminal Sushi domains 1 and 2). Interacts with VSIG4 (By similarity). C3 precursor is first processed by the removal of 4 Arg residues, forming two chains, beta and alpha, linked by a disulfide bond. C3 convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylatoxin and generating C3b (beta chain + alpha' chain).

Function:

Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform has B-cell stimulatory activity.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

1663

Sequence:

50:

100:

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1650:

1663:

AFTESMVVYG | CPN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00207

UniGene:

Mm.19131

String:

P01027

SMR:

P01027

KEGG:

mmu:12266

Uniprot:

P01027

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ELISA Kit for Mouse Complement C3

Cat.:

E0861h

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96T

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ELISA Kit for Mouse Complement C3

Cat.:

E0861m

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96T

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ELISA Kit for Mouse Complement C3

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ELISA Kit for Mouse Complement C3

Cat.:

E0861r

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Packing:

96T

ELISA Kit for Mouse Complement C3

Cat.:

E0861b

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96T

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ELISA Kit for Mouse Complement C3

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CLIA Kit for Mouse Complement C3

Cat.:

U0861b

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Packing:

96T

CLIA Kit for Mouse Complement C3

MSDS:

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CLIA Kit for Mouse Complement C3

Cat.:

U0861r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Complement C3

MSDS:

Please sign in first.

CLIA Kit for Mouse Complement C3

Cat.:

U0861m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Complement C3

Cat.:

U0861h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Complement C3

Cat.:

P0861Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Complement C3

Cat.:

P0861Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Complement C3

Cat.:

P0861Rb-r

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40ug/0.2ml

Monoclonal Antibody for Mouse Complement C3

Protein for Mouse Complement C3

Cat.:

R0861h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Mouse Complement C3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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Citations

[1].

"Using gold nanorods core/silver shell nanostructures as model material to probe biodistribution and toxic effects of silver nanoparticles in mice"

J Meng, Y Ji, J Liu, et al.

From:Nanotoxicology

References

1.

"Nucleotide sequence of complementary DNA and derived amino acid sequence of murine complement protein C3."
Fey G.H. , Lundwall A. , Wetsel R.A. , Tack B.F. , de Bruijn M.H.L. , Domdey H.
Philos. Trans. R. Soc. Lond., B, Biol. Sci.306:333-344(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Liver.
3.

"Structure of murine complement component C3. I. Nucleotide sequence of cloned complementary and genomic DNA coding for the beta chain."
Lundwall A. , Wetsel R.A. , Domdey H. , Tack B.F. , Fey G.H.
J. Biol. Chem.259:13851-13856(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-724 (ISOFORM LONG)
4.

"Isolation and analysis of genomic DNA clones encoding the third component of mouse complement."
Wiebauer K. , Domdey H. , Diggelmann H. , Fey G.
Proc. Natl. Acad. Sci. U.S.A.79:7077-7081(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-34
5.

"Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4."
Sottrup-Jensen L. , Stepanik T.M. , Kristensen T. , Lonblad P.B. , Jones C.M. , Wierzbicki D.M. , Magnusson S. , Domdey H. , Wetsel R.A. , Lundwall A. , Tack B.F. , Fey G.H.
Proc. Natl. Acad. Sci. U.S.A.82:9-13(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 25-1663 (ISOFORM LONG)
6.

"Structure and expression of the C3 gene."
Fey G. , Domdey H. , Wiebauer K. , Whitehead A.S. , Odink K.
Springer Semin. Immunopathol.6:119-147(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 25-240 (ISOFORM LONG)
7.

"A paracrine migration-stimulating factor for metastatic tumor cells secreted by mouse hepatic sinusoidal endothelial cells: identification as complement component C3b."
Hamada J. , Cavanaugh P.G. , Miki K. , Nicolson G.L.
Cancer Res.53:4418-4423(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-41 AND 749-760
8.

"The specific production of the third component of complement by osteoblastic cells treated with 1 alpha,25-dihydroxyvitamin D3."
Sato T. , Hong M.H. , Jin C.H. , Ishimi Y. , Udagawa N. , Shinki T. , Abe E. , Suda T.
FEBS Lett.285:21-24(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-31 AND 671-680
9.

"Amino acid sequences of mouse complement C3 derived from nucleotide sequences of cloned cDNA."
Fey G.H. , Wiebauer K. , Domdey H.
Ann. N. Y. Acad. Sci.421:307-312(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 658-761
10.

"Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain."
Wetsel R.A. , Lundwall A. , Davidson F. , Gibson T. , Tack B.F. , Fey G.H.
J. Biol. Chem.259:13857-13862(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 671-1663 (ISOFORM LONG)
11.

"Characterization of the mRNA and cloned cDNA specifying the third component of mouse complement."
Domdey H. , Wiebauer K. , Kazmaier M. , Mueller V. , Odink K. , Fey G.H.
Proc. Natl. Acad. Sci. U.S.A.79:7619-7623(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 671-748
12.

"The structure of an alternate form of complement C3 that displays costimulatory growth factor activity for B lymphocytes."
Cahen-Kramer Y. , Martensson I.L. , Melchers F.
J. Exp. Med.180:2079-2088(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE INITIATION (ISOFORM SHORT)
13.

"Acylation-stimulating protein (ASP) deficiency induces obesity resistance and increased energy expenditure in ob/ob mice."
Xia Z. , Sniderman A.D. , Cianflone K.
J. Biol. Chem.277:45874-45879(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
14.

"Acylation-stimulating protein deficiency and altered adipose tissue in alternative complement pathway knockout mice."
Paglialunga S. , Fisette A. , Yan Y. , Deshaies Y. , Brouillette J.F. , Pekna M. , Cianflone K.
Am. J. Physiol.294:E521-E529(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION

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