C8G ELISA Kit for Human(Homo sapiens) | EIAab.comC8G ELISA Kit for Human(Homo sapiens)

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Index > Protein center > C8G(Gene name) > Human

C8G (Gene name),

Complement component C8 gamma chain (Protein name ), CO8G_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

C8G;

Protein name:

Complement component C8 gamma chain;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

C8 is composed of three chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded.

Function:

C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

202

Sequence:

50:

100:

150:

200:

202:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00061

STRING:

9606.ENSP00000224181

KEGG:

hsa:733

String:

P07360

SMR:

P07360

UniGene:

Hs.1285

MIM:

120930

Uniprot:

P07360

FOR

ELISA Kit for Human Complement component C8 gamma chain

Cat.:

E14984h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human Complement component C8 gamma chain

Cat.:

E14984m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Complement component C8 gamma chain

MSDS:

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CLIA Kit for Human Complement component C8 gamma chain

Cat.:

U14984h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Complement component C8 gamma chain

Cat.:

U14984m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Complement component C8 gamma chain

MSDS:

Please sign in first.

Polyclonal Antibody for Human Complement component C8 gamma chain

Monoclonal Antibody for Human Complement component C8 gamma chain

Protein for Human Complement component C8 gamma chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes."
Ng S.C. , Rao A.G. , Howard O.M.Z. , Sodetz J.M.
Biochemistry26:5229-5233(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;PYROGLUTAMATE FORMATION AT GLN-21;VARIANT GLY-118
2.

"Structural homology of human complement component C8 gamma and plasma protein HC: identity of the cysteine bond pattern."
Haefliger J.-A. , Jenne D.E. , Stanley K.K. , Tschopp J.
Biochem. Biophys. Res. Commun.149:750-754(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLY-118
tissue: Liver.
3.

"Genomic structure of the human complement protein C8 gamma: homology to the lipocalin gene family."
Kaufman K.M. , Sodetz J.M.
Biochemistry33:5162-5166(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLY-118
tissue: Blood.
4.

"DNA sequence and analysis of human chromosome 9."
Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT GLY-118
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS GLY-118 AND ASN-124
tissue: Colon.
7.

"The homology of complement factor C8 gamma chain and alpha-1-microglobulin."
Hunt L.T. , Elzanowski A. , Barker W.C.
Biochem. Biophys. Res. Commun.149:282-288(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SIMILARITY TO LIPOCALINS
8.

"Structural and functional characterization of complement C8 gamma, a member of the lipocalin protein family."
Haefliger J.-A. , Peitsch M.C. , Jenne D.E. , Tschopp J.
Mol. Immunol.28:123-131(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS;RETINOL-BINDING;3D-STRUCTURE MODELING
9.

"Human complement protein C8 gamma."
Schreck S.F. , Parker C. , Plumb M.E. , Sodetz J.M.
Biochim. Biophys. Acta1482:199-208(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
10.

"Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site."
Ortlund E. , Parker C.L. , Schreck S.F. , Ginell S. , Minor W. , Sodetz J.M. , Lebioda L.
Biochemistry41:7030-7037(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.2 ANGSTROMS) OF 21-202;DISULFIDE BOND
11.

"Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family."
Chiswell B. , Lovelace L.L. , Brannen C. , Ortlund E.A. , Lebioda L. , Sodetz J.M.
Biochim. Biophys. Acta1774:637-644(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 21-202;DISULFIDE BOND
12.

"Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding."
Lovelace L.L. , Chiswell B. , Slade D.J. , Sodetz J.M. , Lebioda L.
Mol. Immunol.45:750-756(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.81 ANGSTROMS) OF 30-202;DISULFIDE BOND

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