Protein name:
Cofilin-1 ;
Alternative:
Cofilin, non-muscle isoform ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Can bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is a major component of intranuclear and cytoplasmic actin rods.
Function:
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis.
Subcellular Location:
Nucleus matrix
Cytoplasm
cytoskeleton
Cell projection
ruffle membrane
Peripheral membrane protein
Cytoplasmic side
Cell projection
lamellipodium membrane
Peripheral membrane protein
Cytoplasmic side
Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock.
Protein Attributes:
50:
MASGVAVSDG | VIKVFNDMKV | RKSSTPEEVK | KRKKAVLFCL | SEDKKNIILE |
100:
EGKEILVGDV | GQTVDDPYTT | FVKMLPDKDC | RYALYDATYE | TKESKKEDLV |
150:
FIFWAPESAP | LKSKMIYASS | KDAIKKKLTG | IKHELQANCY | EEVKDRCTLA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Pig
Bovine
ELISA Kit for Rat Cofilin-1
ELISA Kit for Rat Cofilin-1
ELISA Kit for Rat Cofilin-1
ELISA Kit for Rat Cofilin-1
ELISA Kit for Rat Cofilin-1
CLIA Kit for Rat Cofilin-1
CLIA Kit for Rat Cofilin-1
CLIA Kit for Rat Cofilin-1
CLIA Kit for Rat Cofilin-1
CLIA Kit for Rat Cofilin-1
Polyclonal Antibody for Rat Cofilin-1
Polyclonal Antibody for Rat Cofilin-1
Polyclonal Antibody for Rat Cofilin-1
Polyclonal Antibody for Rat Cofilin-1
Polyclonal Antibody for Rat Cofilin-1
Monoclonal Antibody for Rat Cofilin-1
Monoclonal Antibody for Rat Cofilin-1
Monoclonal Antibody for Rat Cofilin-1
Monoclonal Antibody for Rat Cofilin-1
Monoclonal Antibody for Rat Cofilin-1
Protein for Rat Cofilin-1
Protein for Rat Cofilin-1
Protein for Rat Cofilin-1
Protein for Rat Cofilin-1
Protein for Rat Cofilin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Wistar .
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-166;ACETYLATION AT ALA-2;PHOSPHORYLATION AT SER-3;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Parotid gland .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Ovary .
tissue :
Pituitary .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 35-73; 82-92; 96-112; 133-146 AND 153-166;IDENTIFICATION BY MASS SPECTROMETRY
strain :
Sprague-Dawley .
tissue :
Brain .
tissue :
Hippocampus .
tissue :
Spinal cord .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION AT ALA-2;PHOSPHORYLATION AT SER-3;IDENTIFICATION BY MASS SPECTROMETRY