Gene name:
COL17A1 (BP180;BPAG2) ;
Protein name:
Collagen alpha-1(XVII) chain ;
Alternative:
Bullous pemphigoid antigen 2 ;180 kDa bullous pemphigoid antigen 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homotrimers of alpha 1(XVII)chains. Interacts (via cytoplasmic region) with ITGB4 (via cytoplasmic region). Interacts (via cytoplasmic region) with DST isoform 3 (via N-terminus). Interacts (via N-terminus) with PLEC. Interacts (via cytoplasmic region) with DSP.
Function:
The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.
Subcellular Location:
97 kDa linear IgA disease antigen
Secreted
extracellular space
extracellular matrix
basement membrane
Localized in the lamina lucida beneath the hemidesmosomes.
Protein Attributes:
50:
MDVTKKNKRD | GTEVTERIVT | ETVTTRLTSL | PPKGGTSNGY | AKTASLGGGS |
100:
RLEKQSLTHG | SSGYINSTGS | TRGHASTSSY | RRAHSPASTL | PNSPGSTFER |
150:
KTHVTRHAYE | GSSSGNSSPE | YPRKEFASSS | TRGRSQTRES | EIRVRLQSAS |
200:
PSTRWTELDD | VKRLLKGSRS | ASVSPTRNSS | NTLPIPKKGT | VETKIVTASS |
250:
QSVSGTYDAT | ILDANLPSHV | WSSTLPAGSS | MGTYHNNMTT | QSSSLLNTNA |
300:
YSAGSVFGVP | NNMASCSPTL | HPGLSTSSSV | FGMQNNLAPS | LTTLSHGTTT |
350:
TSTAYGVKKN | MPQSPAAVNT | GVSTSAACTT | SVQSDDLLHK | DCKFLILEKD |
400:
NTPAKKEMEL | LIMTKDSGKV | FTASPASIAA | TSFSEDTLKK | EKQAAYNADS |
450:
GLKAEANGDL | KTVSTKGKTT | TADIHSYGSS | GGGGSGGGGG | VGGAGGGPWG |
500:
PAPAWCPCGS | CCSWWKWLLG | LLLTWLLLLG | LLFGLIALAE | EVRKLKARVD |
550:
ELERIRRSIL | PYGDSMDRIE | KDRLQGMAPA | AGADLDKIGL | HSDSQEELWM |
600:
FVRKKLMMEQ | ENGNLRGSPG | PKGDMGSPGP | KGDRGFPGTP | GIPGPLGHPG |
650:
PQGPKGQKGS | VGDPGMEGPM | GQRGREGPMG | PRGEAGPPGS | GEKGERGAAG |
700:
EPGPHGPPGV | PGSVGPKGSS | GSPGPQGPPG | PVGLQGLRGE | VGLPGVKGDK |
750:
GPMGPPGPKG | DQGEKGPRGL | TGEPGMRGLP | GAVGEPGAKG | AMGPAGPDGH |
800:
QGPRGEQGLT | GMPGIRGPPG | PSGDPGKPGL | TGPQGPQGLP | GTPGRPGIKG |
850:
EPGAPGKIVT | SEGSSMLTVP | GPPGPPGAMG | PPGPPGAPGP | AGPAGLPGHQ |
900:
EVLNLQGPPG | PPGPRGPPGP | SIPGPPGPRG | PPGEGLPGPP | GPPGSFLSNS |
950:
ETFLSGPPGP | PGPPGPKGDQ | GPPGPRGHQG | EQGLPGFSTS | GSSSFGLNLQ |
1000:
GPPGPPGPQG | PKGDKGDPGV | PGALGIPSGP | SEGGSSSTMY | VSGPPGPPGP |
1050:
PGPPGSISSS | GQEIQQYISE | YMQSDSIRSY | LSGVQGPPGP | PGPPGPVTTI |
1100:
TGETFDYSEL | ASHVVSYLRT | SGYGVSLFSS | SISSEDILAV | LQRDDVRQYL |
1150:
RQYLMGPRGP | PGPPGASGDG | SLLSLDYAEL | SSRILSYMSS | SGISIGLPGP |
1200:
PGPPGLPGTS | YEELLSLLRG | SEFRGIVGPP | GPPGPPGIPG | NVWSSISVED |
1250:
LSSYLHTAGL | SFIPGPPGPP | GPPGPRGPPG | VSGALATYAA | ENSDSFRSEL |
1300:
ISYLTSPDVR | SFIVGPPGPP | GPQGPPGDSR | LLSTDASHSR | GSSSSSHSSS |
1350:
VRRGSSYSSS | MSTGGGGAGS | LGAGGAFGEA | AGDRGPYGTD | IGPGGGYGAA |
1400:
AEGGMYAGNG | GLLGADFAGD | LDYNELAVRV | SESMQRQGLL | QGMAYTVQGP |
1450:
PGQPGPQGPP | GISKVFSAYS | NVTADLMDFF | QTYGAIQGPP | GQKGEMGTPG |
1497:
PKGDRGPAGP | PGHPGPPGPR | GHKGEKGDKG | DQVYAGRRRR | RSIAVKP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Dog
Bovine
Chicken
ELISA Kit for Human Collagen alpha-1(XVII) chain
ELISA Kit for Human Collagen alpha-1(XVII) chain
ELISA Kit for Human Collagen alpha-1(XVII) chain
ELISA Kit for Human Collagen alpha-1(XVII) chain
ELISA Kit for Human Collagen alpha-1(XVII) chain
CLIA Kit for Human Collagen alpha-1(XVII) chain
CLIA Kit for Human Collagen alpha-1(XVII) chain
CLIA Kit for Human Collagen alpha-1(XVII) chain
CLIA Kit for Human Collagen alpha-1(XVII) chain
CLIA Kit for Human Collagen alpha-1(XVII) chain
Polyclonal Antibody for Human Collagen alpha-1(XVII) chain
Polyclonal Antibody for Human Collagen alpha-1(XVII) chain
Polyclonal Antibody for Human Collagen alpha-1(XVII) chain
Polyclonal Antibody for Human Collagen alpha-1(XVII) chain
Polyclonal Antibody for Human Collagen alpha-1(XVII) chain
Monoclonal Antibody for Human Collagen alpha-1(XVII) chain
Monoclonal Antibody for Human Collagen alpha-1(XVII) chain
Monoclonal Antibody for Human Collagen alpha-1(XVII) chain
Monoclonal Antibody for Human Collagen alpha-1(XVII) chain
Monoclonal Antibody for Human Collagen alpha-1(XVII) chain
Protein for Human Collagen alpha-1(XVII) chain
Protein for Human Collagen alpha-1(XVII) chain
Protein for Human Collagen alpha-1(XVII) chain
Protein for Human Collagen alpha-1(XVII) chain
Protein for Human Collagen alpha-1(XVII) chain
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;VARIANT SER-428
tissue :
Foreskin .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANTS ILE-231; THR-238; SER-428; VAL-703 AND GLY-1370
3.
"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P.
,
Earthrowl M.E.
,
Grafham D.V.
,
Rubenfield M.
,
French L.
,
Steward C.A.
,
Sims S.K.
,
Jones M.C.
,
Searle S.
,
Scott C.
,
Howe K.
,
Hunt S.E.
,
Andrews T.D.
,
Gilbert J.G.R.
,
Swarbreck D.
,
Ashurst J.L.
,
Taylor A.
,
Battles J.
,
Bird C.P.
,
Ainscough R.
,
Almeida J.P.
,
Ashwell R.I.S.
,
Ambrose K.D.
,
Babbage A.K.
,
Bagguley C.L.
,
Bailey J.
,
Banerjee R.
,
Bates K.
,
Beasley H.
,
Bray-Allen S.
,
Brown A.J.
,
Brown J.Y.
,
Burford D.C.
,
Burrill W.
,
Burton J.
,
Cahill P.
,
Camire D.
,
Carter N.P.
,
Chapman J.C.
,
Clark S.Y.
,
Clarke G.
,
Clee C.M.
,
Clegg S.
,
Corby N.
,
Coulson A.
,
Dhami P.
,
Dutta I.
,
Dunn M.
,
Faulkner L.
,
Frankish A.
,
Frankland J.A.
,
Garner P.
,
Garnett J.
,
Gribble S.
,
Griffiths C.
,
Grocock R.
,
Gustafson E.
,
Hammond S.
,
Harley J.L.
,
Hart E.
,
Heath P.D.
,
Ho T.P.
,
Hopkins B.
,
Horne J.
,
Howden P.J.
,
Huckle E.
,
Hynds C.
,
Johnson C.
,
Johnson D.
,
Kana A.
,
Kay M.
,
Kimberley A.M.
,
Kershaw J.K.
,
Kokkinaki M.
,
Laird G.K.
,
Lawlor S.
,
Lee H.M.
,
Leongamornlert D.A.
,
Laird G.
,
Lloyd C.
,
Lloyd D.M.
,
Loveland J.
,
Lovell J.
,
McLaren S.
,
McLay K.E.
,
McMurray A.
,
Mashreghi-Mohammadi M.
,
Matthews L.
,
Milne S.
,
Nickerson T.
,
Nguyen M.
,
Overton-Larty E.
,
Palmer S.A.
,
Pearce A.V.
,
Peck A.I.
,
Pelan S.
,
Phillimore B.
,
Porter K.
,
Rice C.M.
,
Rogosin A.
,
Ross M.T.
,
Sarafidou T.
,
Sehra H.K.
,
Shownkeen R.
,
Skuce C.D.
,
Smith M.
,
Standring L.
,
Sycamore N.
,
Tester J.
,
Thorpe A.
,
Torcasso W.
,
Tracey A.
,
Tromans A.
,
Tsolas J.
,
Wall M.
,
Walsh J.
,
Wang H.
,
Weinstock K.
,
West A.P.
,
Willey D.L.
,
Whitehead S.L.
,
Wilming L.
,
Wray P.W.
,
Young L.
,
Chen Y.
,
Lovering R.C.
,
Moschonas N.K.
,
Siebert R.
,
Fechtel K.
,
Bentley D.
,
Durbin R.M.
,
Hubbard T.
,
Doucette-Stamm L.
,
Beck S.
,
Smith D.R.
,
Rogers J.
more...
Nature429:375-381(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-390;VARIANT MET-210
tissue :
Pancreas .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 508-856;TISSUE SPECIFICITY
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 524-535
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 531-546; 554-565; 585-605; 647-666; 680-688; 689-703; 755-765; 842-860; 880-891; 1016-1028; 1062-1069; 1102-1108; 1134-1142; 1227-1247 AND 1248-1260
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;FUNCTION;TISSUE SPECIFICITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT;PROTEOLYTIC PROCESSING;GLYCOSYLATION AT ASN-1421;DOMAINS
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DSP
14.
"Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs."
Franzke C.-W.
,
Tasanen K.
,
Schaecke H.
,
Zhou Z.
,
Tryggvason K.
,
Mauch C.
,
Zigrino P.
,
Sunnarborg S.
,
Lee D.C.
,
Fahrenholz F.
,
Bruckner-Tuderman L.
EMBO J.21:5026-5035(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SHEDDING
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH DSP; DST; ITGB4 AND PLEC;SUBCELLULAR LOCATION
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-544
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT GABEB VAL-627
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT GABEB GLN-1303
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT GABEB VAL-627
21.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT GABEB ASP-633
22.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT GABEB CYS-265;VARIANT ILE-231