POMC ELISA Kit for Human(Homo sapiens) | EIAab.comPOMC ELISA Kit for Human(Homo sapiens)

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Index > Protein center > POMC(Gene name) > Human

POMC (Gene name),

Pro-opiomelanocortin (Protein name ), COLI_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

POMC;

Protein name:

Pro-opiomelanocortin(POMC);

Alternative:

Corticotropin-lipotropin;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Beta-endorphin and Met-enkephalin are endogenous opiates.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

267

Sequence:

50:

100:

150:

200:

250:

267:

VTLFKNAIIK | NAYKKGE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00976

MIM:

176830

UniGene:

Hs.1897

STRING:

9606.ENSP00000264708

KEGG:

hsa:5443

String:

P01189

Uniprot:

P01189

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ELISA Kit for Human POMC

Cat.:

E1311p

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Packing:

96T

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ELISA Kit for Human POMC

Cat.:

E1311m

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96T

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ELISA Kit for Human POMC

Cat.:

E1311h

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96T

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ELISA Kit for Human POMC

MSDS:

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ELISA Kit for Human POMC

Cat.:

E1311b

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MSDS:

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Packing:

96T

ELISA Kit for Human POMC

Cat.:

E1311r

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MSDS:

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Packing:

96T

CLIA Kit for Human POMC

Cat.:

U1311r

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Packing:

96T

CLIA Kit for Human POMC

Cat.:

U1311m

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MSDS:

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Packing:

96T

CLIA Kit for Human POMC

Cat.:

U1311h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human POMC

MSDS:

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CLIA Kit for Human POMC

Cat.:

U1311p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human POMC

Cat.:

U1311b

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96T

Polyclonal Antibody for Human POMC

Cat.:

P1311Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human POMC

Cat.:

P1311Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human POMC

Cat.:

P1311Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human POMC

Protein for Human POMC

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Isolation and structural organization of the human corticotropin-beta-lipotropin precursor gene."
Takahashi H. , Teranishi Y. , Nakanishi S. , Numa S.
FEBS Lett.135:97-102(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"The human pro-opiomelanocortin gene: organization, sequence, and interspersion with repetitive DNA."
Whitfeld P.L. , Seeburg P.H. , Shine J.
DNA1:133-143(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Complete nucleotide sequence of the human corticotropin-beta-lipotropin precursor gene."
Takahashi H. , Hakamata Y. , Watanabe Y. , Kikuno R. , Miyata T. , Numa S.
Nucleic Acids Res.11:6847-6858(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pituitary.
7.

"Synthesis, cloning and primary structure of DNA complementary to mRNA for human pituitary pro-opiomelanocortin."
Golovin S.Y. , Karginov V.A. , Bondar A.A. , Beklemishev A.B. , Chekhranova M.K. , Mertvetsov N.P. , Pankov Y.A.
Bioorg. Khim.13:562-564(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-267
8.

"Structural organization of human genomic DNA encoding the pro-opiomelanocortin peptide."
Chang A.C.Y. , Cochet M. , Cohen S.N.
Proc. Natl. Acad. Sci. U.S.A.77:4890-4894(1980) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 46-267
9.

"Complete amino acid sequence of a human pituitary glycopeptide: an important maturation product of pro-opiomelanocortin."
Seidah N.G. , Chretien M.
Proc. Natl. Acad. Sci. U.S.A.78:4236-4240(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 27-102
10.

"Primary structure of the major human pituitary pro-opiomelanocortin NH2-terminal glycopeptide. Evidence for an aldosterone-stimulating activity."
Seidah N.G. , Rochemont J. , Hamelin J. , Lis M. , Chretien M.
J. Biol. Chem.256:7977-7984(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 27-102
11.

"The missing fragment of the pro-sequence of human pro-opiomelanocortin: sequence and evidence for C-terminal amidation."
Seidah N.G. , Rochemont J. , Hamelin J. , Benjannet S. , Chretien M.
Biochem. Biophys. Res. Commun.102:710-716(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 105-134;AMIDATION AT GLU-134
12.

"Confirmation of the 1-20 amino acid sequence of human adrenocorticotrophin."
Bennett H.P.J. , Lowry P.J. , McMartin C.
Biochem. J.133:11-13(1973) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 138-176
13.

"On the structure of human corticotropin (adrenocorticotropic hormone)."
Lee T.H. , Lerner A.B. , Buettner-Janusch V.
J. Biol. Chem.236:2970-2974(1961) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 138-176
14.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 27-41
15.

"Revised amino-acid sequences for porcine and human adrenocorticotrophic hormone."
Riniker B. , Sieber P. , Rittel W. , Zuber H.
Nature New Biol.235:114-115(1972) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION (CORTICOTROPIN)
16.

"Synthesis of the human adrenal cortex hormone (alpha-h-ACTH) with a revised amino-acid sequence."
Sieber P. , Rittel W. , Riniker B.
Helv. Chim. Acta55:1243-1266(1972) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SYNTHESIS OF CORTICOTROPIN
17.

"Adrenocorticotropins. 44. Total synthesis of the human hormone by the solid-phase method."
Yamashiro D. , Li C.H.
J. Am. Chem. Soc.95:1310-1315(1973) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SYNTHESIS OF CORTICOTROPIN
18.

"Primary structure of human beta-lipotropin."
Li C.H. , Chung D.
Nature260:622-624(1976) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 179-267
19.

"Structure of a melanocyte-stimulating hormone from the human pituitary gland."
Harris J.I.
Nature184:167-169(1959)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 217-234
20.

"Primary structure and morphine-like activity of human beta-endorphin."
Dragon N. , Seidah N.G. , Lis M. , Routhier R. , Chretien M.
Can. J. Biochem.55:666-670(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 237-267
21.

"Gamma-endorphin and schizophrenia: amino acid composition of gamma-endorphin and nucleotide sequence of gamma-endorphin cDNA from pituitary glands of schizophrenic patients."
Bovenberg R.A.L. , Burbach J.P.H. , Wiegant V.M. , Veeneman G.H. , van Boom J.H. , Baas P.D. , Jansz H.S. , de Wied D.
Brain Res.376:29-37(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 235-256
22.

"Alpha-amidated peptides derived from pro-opiomelanocortin in normal human pituitary."
Fenger M. , Johnsen A.H.
Biochem. J.250:781-788(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
23.

"Reduced expression of a naturally deleted form of human proopiomelanocortin complementary deoxyribonucleic acid after transfection into Chinese hamster ovary cells."
Morris J.C. , Savva D. , Lowry P.J.
Endocrinology136:195-201(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 75-104;VARIANT 97-SER--GLY-99 DEL
tissue: Pituitary.
24.

"Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans."
Krude H. , Biebermann H. , Luck W. , Horn R. , Brabant G. , Grueters A.
Nat. Genet.19:155-157(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN POMCD
25.

"Association between common polymorphisms of the proopiomelanocortin gene and body fat distribution: a family study."
Baker M. , Gaukrodger N. , Mayosi B.M. , Imrie H. , Farrall M. , Watkins H. , Connell J.M.C. , Avery P.J. , Keavney B.
Diabetes54:2492-2496(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ABDOMINAL BODY FAT DISTRIBUTION
26.

"Phosphoproteomic analysis of the human pituitary."
Beranova-Giorgianni S. , Zhao Y. , Desiderio D.M. , Giorgianni F.
Pituitary9:109-120(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-168;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Pituitary.
27.

"Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes."
Hinney A. , Becker I. , Heibult O. , Nottebom K. , Schmidt A. , Ziegler A. , Mayer H. , Siegfried W. , Blum W.F. , Remschmidt H. , Hebebrand J.
J. Clin. Endocrinol. Metab.83:3737-3741(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ASN-106; GLY-214 AND 97-SER--GLY-99 DEL
28.

"Mutational analysis of the proopiomelanocortin gene in Caucasians with early onset obesity."
Echwald S.M. , Sorensen T.I. , Andersen T. , Tybjaerg-Hansen A. , Clausen J.O. , Pedersen O.
Int. J. Obes. Relat. Metab. Disord.23:293-298(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLN-236
29.

"Molecular screening of the proopiomelanocortin (POMC) gene in Italian obese children: report of three new mutations."
del Giudice E.M. , Cirillo G. , Santoro N. , D'Urso L. , Carbone M.T. , Toro R.D. , Perrone L.
Int. J. Obes. Relat. Metab. Disord.25:61-67(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS THR-7; LEU-9; GLY-236 AND 97-SER--GLY-99 DEL
30.

"A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism."
Challis B.G. , Pritchard L.E. , Creemers J.W.M. , Delplanque J. , Keogh J.M. , Luan J. , Wareham N.J. , Yeo G.S.H. , Bhattacharyya S. , Froguel P. , White A. , Farooqi I.S. , O'Rahilly S.
Hum. Mol. Genet.11:1997-2004(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLY-236;CHARACTERIZATION OF VARIANT GLY-236;POSSIBLE INVOLVEMENT IN OBESITY

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