Coro1a ELISA Kit for Mouse(Mus musculus) | EIAab.comCoro1a ELISA Kit for Mouse(Mus musculus)

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Coro1a (Gene name),

Coronin-1A (Protein name ), COR1A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Coro1a(Coro1);

Protein name:

Coronin-1A;

Alternative:

Coronin-like protein p57;Coronin-like protein A(Clipin-A);Tryptophan aspartate-containing coat protein(TACO);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds actin.

Function:

May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.

Subcellular Location:

Cytoplasm cytoskeleton Cytoplasm cell cortex Cytoplasmic vesicle phagosome membrane In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification.

Protein Attributes:

Sequence length:

461

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

461:

LDRLEETVQA | K

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O89053

Pfam:

PF08953

KEGG:

mmu:12721

SMR:

O89053

UniGene:

Mm.290482

Uniprot:

O89053

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ELISA Kit for Mouse Coronin-1A

Cat.:

E0023m

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Packing:

96T

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ELISA Kit for Mouse Coronin-1A

Cat.:

E0023r

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96T

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ELISA Kit for Mouse Coronin-1A

Cat.:

E0023h

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96T

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ELISA Kit for Mouse Coronin-1A

Cat.:

E0023b

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Packing:

96T

CLIA Kit for Mouse Coronin-1A

Cat.:

U0023b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Coronin-1A

Cat.:

U0023h

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MSDS:

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Packing:

96T

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CLIA Kit for Mouse Coronin-1A

Cat.:

U0023m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Coronin-1A

Cat.:

U0023r

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96T

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Polyclonal Antibody for Mouse Coronin-1A

Cat.:

P0023Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Coronin-1A

Cat.:

P0023Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Coronin-1A

Cat.:

P0023Rb-h

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40ug/0.2ml

Monoclonal Antibody for Mouse Coronin-1A

Protein for Mouse Coronin-1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein."
Okumura M. , Kung C. , Wong S. , Rodgers M. , Thomas M.L.
DNA Cell Biol.17:779-787(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"A coat protein on phagosomes involved in the intracellular survival of mycobacteria."
Ferrari G. , Langen H. , Naito M. , Pieters J.
Cell97:435-447(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 11-14;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;ROLE IN PHAGOSOME TRAFFICKING
strain: C57BL/6.
tissue: Macrophage.
3.

"A new therapeutic strategy of mycobacterium infection by use of anti-TACO sequence."
Kohchi C. , Inagawa H. , Makino K. , Terada H. , Soma G.
Submitted (2002-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Hematopoietic.
tissue: Mammary tumor.
5.

"Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis."
Chu C.C. , Paul W.E.
Mol. Immunol.35:487-502(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 156-276
strain: BALB/c.
tissue: Spleen.
6.

Lubec G. , Klug S.
Submitted (2007-03) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 215-233;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Hippocampus.
7.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-418;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.

"Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin."
Oku T. , Nakano M. , Kaneko Y. , Ando Y. , Kenmotsu H. , Itoh S. , Tsuiji M. , Seyama Y. , Toyoshima S. , Tsuji T.
J. Biol. Chem.287:42910-42920(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-412
9.

"A conserved trimerization motif controls the topology of short coiled coils."
Kammerer R.A. , Kostrewa D. , Progias P. , Honnappa S. , Avila D. , Lustig A. , Winkler F.K. , Pieters J. , Steinmetz M.O.
Proc. Natl. Acad. Sci. U.S.A.102:13891-13896(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.2 ANGSTROMS) OF 430-461;COILED-COIL DOMAIN
10.

"The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes."
Appleton B.A. , Wu P. , Wiesmann C.
Structure14:87-96(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 1-402;WD REPEATS;COILED-COIL DOMAIN

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