COTL1 ELISA Kit for Human(Homo sapiens) | EIAab.comCOTL1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > COTL1(Gene name) > Human

COTL1 (Gene name),

Coactosin-like protein (Protein name ), COTL1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

COTL1(CLP);

Protein name:

Coactosin-like protein;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with 5-lipoxygenase (5LO) in a calcium-independent manner.

Function:

Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.

Subcellular Location:

Cytoplasm cytoskeleton

Protein Attributes:

Sequence length:

142

Sequence:

50:

100:

142:

VKEVVQNFAK | EFVISDRKEL | EEDFIKSELK | KAGGANYDAQ | TE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000262428

UniGene:

Hs.289092

KEGG:

hsa:23406

String:

Q14019

MIM:

606748

SMR:

Q14019

Pfam:

PF00241

Uniprot:

Q14019

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ELISA Kit for Human Coactosin-like protein

Cat.:

E1238h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human Coactosin-like protein

Cat.:

E1238b

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MSDS:

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Packing:

96T

ELISA Kit for Human Coactosin-like protein

Cat.:

E1238r

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Packing:

96T

ELISA Kit for Human Coactosin-like protein

Cat.:

E1238m

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MSDS:

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Packing:

96T

CLIA Kit for Human Coactosin-like protein

Cat.:

U1238m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Coactosin-like protein

Cat.:

U1238r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Coactosin-like protein

Cat.:

U1238b

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Coactosin-like protein

Cat.:

U1238h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Coactosin-like protein

Cat.:

P1238Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Coactosin-like protein

Cat.:

P1238Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Coactosin-like protein

Cat.:

P1238Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Coactosin-like protein

Protein for Human Coactosin-like protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome."
Chen K.-S. , Manian P. , Koeuth T. , Potocki L. , Zhao Q. , Chinault A.C. , Lee C.-C. , Lupski J.R.
Nat. Genet.17:154-163(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Placenta.
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Cervix.
tissue: Kidney.
tissue: Lung.
tissue: Uterus.
6.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-11
tissue: Platelet.
7.

Lubec G. , Afjehi-Sadat L.
Submitted (2007-03) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 76-91;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
8.

"Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75."
Provost P. , Doucet J. , Stock A. , Gerisch G. , Samuelsson B. , Radmark O.
Biochem. J.359:255-263(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF LYS-75
9.

"5-lipoxygenase interacts with coactosin-like protein."
Provost P. , Doucet J. , Hammarberg T. , Gerisch G. , Samuelsson B. , Radmark O.
J. Biol. Chem.276:16520-16527(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH 5-LIPOXYGENASE;MUTAGENESIS OF LYS-130 AND LYS-131
10.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-102 AND LYS-126;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102."
Esser J. , Rakonjac M. , Hofmann B. , Fischer L. , Provost P. , Schneider G. , Steinhilber D. , Samuelsson B. , Radmark O.
Biochem. J.425:265-274(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
14.

"NMR structure of human coactosin-like protein."
Liepinsh E. , Rakonjac M. , Boissonneault V. , Provost P. , Samuelsson B. , Radmark O. , Otting G.
J. Biomol. NMR30:353-356(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
15.

"Crystal structure of human coactosin-like protein at 1.9 A resolution."
Li X. , Liu X. , Lou Z. , Duan X. , Wu H. , Liu Y. , Rao Z.
Protein Sci.13:2845-2851(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS);SUBUNIT
16.

"Binding model of human coactosin-like protein with filament actin revealed by mutagenesis."
Dai H. , Huang W. , Xu J. , Yao B. , Xiong S. , Ding H. , Tang Y. , Liu H. , Wu J. , Shi Y.
Biochim. Biophys. Acta1764:1688-1700(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR;SUBUNIT;F-ACTIN BINDING REGION

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