CYP11A1 ELISA Kit for Human(Homo sapiens) | EIAab.comCYP11A1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CYP11A1(Gene name) > Human

CYP11A1 (Gene name),

Cholesterol side-chain cleavage enzyme, mitochondrial (Protein name ), CP11A_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CYP11A1(CYP11A);

Protein name:

Cholesterol side-chain cleavage enzyme, mitochondrial;

Alternative:

Cholesterol desmolase;CYPXIA1;Cytochrome P450(scc);Cytochrome P450 11A1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.

Subcellular Location:

Mitochondrion membrane

Protein Attributes:

Sequence length:

521

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

521:

LMPEKPISFT | FWPFNQEATQ | Q

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P05108

STRING:

9606.ENSP00000268053

MIM:

118485

UniGene:

Hs.303980

KEGG:

hsa:1583

Pfam:

PF00067

SMR:

P05108

Uniprot:

P05108

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ELISA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

E0987b

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96T

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ELISA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

E0987m

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Packing:

96T

ELISA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

E0987h

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96T

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ELISA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

E0987p

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MSDS:

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Packing:

96T

ELISA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

E0987r

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96T

ELISA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

MSDS:

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CLIA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

U0987r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

U0987m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

U0987h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

MSDS:

Please sign in first.

CLIA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

U0987p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

U0987b

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

P0987Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

P0987Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Cat.:

P0987Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Cholesterol side-chain cleavage enzyme, mitochondrial

Protein for Human Cholesterol side-chain cleavage enzyme, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta."
Chung B.-C. , Matteson K.J. , Voutilainen R. , Mohandas T.K. , Miller W.L.
Proc. Natl. Acad. Sci. U.S.A.83:8962-8966(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Gene structure of human cytochrome P-450(SCC), cholesterol desmolase."
Morohashi K. , Sogawa K. , Omura T. , Fujii-Kuriyama Y.
J. Biochem.101:879-887(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Placenta.
tissue: Testis.
4.

"Analysis of the DNA sequence and duplication history of human chromosome 15."
Zody M.C. , Garber M. , Sharpe T. , Young S.K. , Rowen L. , O'Neill K. , Whittaker C.A. , Kamal M. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Kodira C.D. , Madan A. , Qin S. , Yang X. , Abbasi N. , Abouelleil A. , more...
Nature440:671-675(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
7.

Chung B.-C.
Submitted (1989-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-89
8.

"Regulated expression of cytochrome P-450scc (cholesterol-side-chain cleavage enzyme) in cultured cell lines detected by antibody against bacterially expressed human protein."
Hu M.C. , Guo I.C. , Lin J.H. , Chung B.-C.
Biochem. J.274:813-817(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 51-54;INDUCTION
tissue: Choriocarcinoma.
9.

"Study of cholesterol side-chain cleavage (20,22 desmolase) deficiency causing congenital lipoid adrenal hyperplasia using bovine-sequence P450scc oligodeoxyribonucleotide probes."
Matteson K.J. , Chung B.-C. , Urdea M.S. , Miller W.L.
Endocrinology118:1296-1305(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 283-521 (ISOFORM 1)
10.

"Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system."
Strushkevich N. , MacKenzie F. , Cherkesova T. , Grabovec I. , Usanov S. , Park H.W.
Proc. Natl. Acad. Sci. U.S.A.108:10139-10143(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 41-521 IN COMPLEXES WITH FDX1; HEME AND CHOLESTEROL;FUNCTION;CATALYTIC ACTIVITY;COFACTOR;PATHWAY;INTERACTION WITH FDX1
11.

"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.22:231-238(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LYS-314
12.

Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.23:373-373(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
13.

"Heterozygous mutation in the cholesterol side chain cleavage enzyme (P450scc) gene in a patient with 46,XY sex reversal and adrenal insufficiency."
Tajima T. , Fujieda K. , Kouda N. , Nakae J. , Miller W.L.
J. Clin. Endocrinol. Metab.86:3820-3825(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AICSR GLY-ASP-271 INS
14.

"Compound heterozygous mutations in the cholesterol side-chain cleavage enzyme gene (CYP11A) cause congenital adrenal insufficiency in humans."
Katsumata N. , Ohtake M. , Hojo T. , Ogawa E. , Hara T. , Sato N. , Tanaka T.
J. Clin. Endocrinol. Metab.87:3808-3813(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AICSR VAL-189 AND TRP-353
15.

"Homozygous mutation of P450 side-chain cleavage enzyme gene (CYP11A1) in 46, XY patient with adrenal insufficiency, complete sex reversal, and agenesis of corpus callosum."
al Kandari H. , Katsumata N. , Alexander S. , Rasoul M.A.
J. Clin. Endocrinol. Metab.91:2821-2826(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AICSR VAL-359;CHARACTERIZATION OF VARIANT AICSR VAL-359
16.

"Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc."
Kim C.J. , Lin L. , Huang N. , Quigley C.A. , Avruskin T.W. , Achermann J.C. , Miller W.L.
J. Clin. Endocrinol. Metab.93:696-702(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AICSR TRP-141 AND GLU-415;CHARACTERIZATION OF VARIANTS AICSR TRP-141 AND GLU-415
17.

"A novel homozygous mutation in CYP11A1 gene is associated with late-onset adrenal insufficiency and hypospadias in a 46,XY patient."
Rubtsov P. , Karmanov M. , Sverdlova P. , Spirin P. , Tiulpakov A.
J. Clin. Endocrinol. Metab.94:936-939(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AICSR PRO-222;CHARACTERIZATION OF VARIANT AICSR PRO-222

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