CYP1A1 ELISA Kit for Human(Homo sapiens) | EIAab.comCYP1A1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CYP1A1(Gene name) > Human

CYP1A1 (Gene name),

Cytochrome P450 1A1 (Protein name ), CP1A1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CYP1A1;

Protein name:

Cytochrome P450 1A1;

Alternative:

Cytochrome P450 form 6;CYPIA1;Cytochrome P450-P1;Cytochrome P450-C;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Subcellular Location:

Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein

Protein Attributes:

Sequence length:

512

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

512:

ACCEHFQMQL | RS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P04798

STRING:

9606.ENSP00000369050

UniGene:

Hs.72912

MIM:

108330

Pfam:

PF00067

KEGG:

hsa:1543

SMR:

P04798

Uniprot:

P04798

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ELISA Kit for Human Cytochrome P450 1A1

Cat.:

E10138r

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Packing:

96T

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ELISA Kit for Human Cytochrome P450 1A1

MSDS:

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ELISA Kit for Human Cytochrome P450 1A1

Cat.:

E10138h

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96T

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ELISA Kit for Human Cytochrome P450 1A1

Cat.:

E10138m

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96T

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ELISA Kit for Human Cytochrome P450 1A1

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CLIA Kit for Human Cytochrome P450 1A1

Cat.:

U10138r

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MSDS:

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Packing:

96T

CLIA Kit for Human Cytochrome P450 1A1

Cat.:

U10138h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human Cytochrome P450 1A1

MSDS:

Please sign in first.

CLIA Kit for Human Cytochrome P450 1A1

MSDS:

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CLIA Kit for Human Cytochrome P450 1A1

Cat.:

U10138m

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Packing:

96T

Polyclonal Antibody for Human Cytochrome P450 1A1

Cat.:

P10138Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Cytochrome P450 1A1

Protein for Human Cytochrome P450 1A1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism."
Jaiswal A.K. , Gonzales F.J. , Nebert D.W.
Nucleic Acids Res.13:4503-4520(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Human dioxin-inducible cytochrome P1-450: complementary DNA and amino acid sequence."
Jaiswal A.K. , Gonzalez F.J. , Nebert D.W.
Science228:80-83(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Structure and drug inducibility of the human cytochrome P-450c gene."
Kawajiri K. , Watanabe J. , Gotoh O. , Tagashira Y. , Sogawa K. , Fujii-Kuriyama Y.
Eur. J. Biochem.159:219-225(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
4.

"Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation."
Corchero J. , Pimprale S. , Kimura S. , Gonzalez F.J.
Pharmacogenetics11:1-6(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Cloning and sequencing of new alternative splicing variants of human CYP1A1 gene."
Graebsch C. , Bauer M.
Submitted (2006-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3)
tissue: Blood.
6.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ASP-45
7.

"Analysis of the DNA sequence and duplication history of human chromosome 15."
Zody M.C. , Garber M. , Sharpe T. , Young S.K. , Rowen L. , O'Neill K. , Whittaker C.A. , Kamal M. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Kodira C.D. , Madan A. , Qin S. , Yang X. , Abbasi N. , Abouelleil A. , more...
Nature440:671-675(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Cervix.
9.

"Identification of cytochrome P450 1A1 in human brain."
Yun C.H. , Park H.J. , Kim S.J. , Kim H.K.
Biochem. Biophys. Res. Commun.243:808-810(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 282-425 (ISOFORM 1)
tissue: Brain.
10.

"Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6."
Quattrochi L.C. , Okino S.T. , Pendurthi U.R. , Tukey R.H.
DNA4:395-400(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 295-484 (ISOFORM 1)
11.

"Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism."
Walsh A.A. , Szklarz G.D. , Scott E.E.
J. Biol. Chem.288:12932-12943(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 35-512 IN COMPLEX WITH HEME AND INHIBITOR ALPHA-NAPHTOFLAVONE;COFACTOR
12.

"Genetic linkage of lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene."
Hayashi S. , Watanabe J. , Nakachi K. , Kawajiri K.
J. Biochem.110:407-411(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT VAL-462
13.

"A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility."
Cascorbi I. , Brockmoller J. , Roots I.
Cancer Res.56:4965-4969(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-461
14.

"Variation in induced CYP1A1 levels: relationship to CYP1A1, Ah receptor and GSTM1 polymorphisms."
Smart J. , Daly A.K.
Pharmacogenetics10:11-24(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TRP-279
15.

"Detection of known and two novel (M331I and R464S) missense mutations in the human CYP1A1 gene in a French Caucasian population."
Chevalier D. , Allorge D. , Lo-Guidice J.-M. , Cauffiez C. , Lhermitte M. , Lafitte J.-J. , Broly F.
Hum. Mutat.17:355-355(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ILE-331 AND SER-464
16.

"Novel nonsynonymous polymorphisms of the CYP1A1 Gene in Japanese."
Saito M. , Egashira M. , Kiyotani K. , Fujieda M. , Yamazaki H. , Kiyohara C. , Kunitoh H. , Kamataki T.
Drug Metab. Pharmacokinet.18:218-222(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ASN-448; CYS-464; TRP-477 AND ARG-492
17.

"Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population."
Solus J.F. , Arietta B.J. , Harris J.R. , Sexton D.P. , Steward J.Q. , McMunn C. , Ihrie P. , Mehall J.M. , Edwards T.L. , Dawson E.P.
Pharmacogenomics5:895-931(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ASP-45; THR-78; TRP-93; ARG-173; ASN-461; MET-482 AND ARG-492
18.

"Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus."
Jiang Z. , Dalton T.P. , Jin L. , Wang B. , Tsuneoka Y. , Shertzer H.G. , Deka R. , Nebert D.W.
Hum. Mutat.25:196-206(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ASP-45; THR-78; ASN-461 AND VAL-462
19.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] TRP-477

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