CYP7A1 ELISA Kit for Human(Homo sapiens) | EIAab.comCYP7A1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CYP7A1(Gene name) > Human

CYP7A1 (Gene name),

Cholesterol 7-alpha-monooxygenase (Protein name ), CP7A1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CYP7A1(CYP7);

Protein name:

Cholesterol 7-alpha-monooxygenase;

Alternative:

Cholesterol 7-alpha-hydroxylase;CYPVII;Cytochrome P450 7A1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.

Subcellular Location:

Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein

Protein Attributes:

Sequence length:

504

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

504:

FKHL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P22680

MIM:

118455

SMR:

P22680

KEGG:

hsa:1581

UniGene:

Hs.1644

Pfam:

PF00067

STRING:

9606.ENSP00000301645

Uniprot:

P22680

FOR

ELISA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

E1053h

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96T

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ELISA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

E1053r

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96T

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ELISA Kit for Human Cholesterol 7-alpha-monooxygenase

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ELISA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

E1053m

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96T

ELISA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

E1053p

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96T

CLIA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

U1053m

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96T

CLIA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

U1053p

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Packing:

96T

CLIA Kit for Human Cholesterol 7-alpha-monooxygenase

MSDS:

Please sign in first.

CLIA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

U1053r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Cholesterol 7-alpha-monooxygenase

Cat.:

U1053h

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96T

Polyclonal Antibody for Human Cholesterol 7-alpha-monooxygenase

Cat.:

P1053Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Cholesterol 7-alpha-monooxygenase

Cat.:

P1053Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Cholesterol 7-alpha-monooxygenase

Cat.:

P1053Rb-r

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Monoclonal Antibody for Human Cholesterol 7-alpha-monooxygenase

Protein for Human Cholesterol 7-alpha-monooxygenase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Structure of the gene encoding human liver cholesterol 7 alpha-hydroxylase."
Nishimoto M. , Noshiro M. , Okuda K.
Biochim. Biophys. Acta1172:147-150(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase."
Noshiro M. , Okuda K.
FEBS Lett.268:137-140(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CATALYTIC ACTIVITY;VARIANT ASN-347
3.

"Polymorphisms of human cholesterol 7 alpha-hydroxylase."
Karam W.G. , Chiang J.Y.
Biochem. Biophys. Res. Commun.185:588-595(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-100
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
5.

"Structure and nucleotide sequences of the human cholesterol 7 alpha-hydroxylase gene (CYP7)."
Wang D.P. , Chiang J.Y.
Genomics20:320-323(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-140
tissue: Placenta.
6.

"Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene."
Molowa D.T. , Chen W.S. , Cimis G.M. , Tan C.P.
Biochemistry31:2539-2544(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-25
7.

"Feedback regulation of bile acid synthesis in human liver: importance of HNF-4alpha for regulation of CYP7A1."
Abrahamsson A. , Gustafsson U. , Ellis E. , Nilsson L.M. , Sahlin S. , Bjorkhem I. , Einarsson C.
Biochem. Biophys. Res. Commun.330:395-399(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY CHENODEOXYCHOLIC ACID AND CHOLESTYRAMINE;TISSUE SPECIFICITY
8.

"Glucose stimulates cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes."
Li T. , Chanda D. , Zhang Y. , Choi H.S. , Chiang J.Y.
J. Lipid Res.51:832-842(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY GLUCOSE;FUNCTION
9.

"Crystal structure of human CYP7A1."
Structural genomics consortium (SGC)
Submitted (2009-02) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) IN COMPLEX WITH HEME;COFACTOR
10.

"Catalog of 680 variations among eight cytochrome p450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population."
Saito S. , Iida A. , Sekine A. , Kawauchi S. , Higuchi S. , Ogawa C. , Nakamura Y.
J. Hum. Genet.48:249-270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SER-233 AND ASN-347

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