Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > CR2(Gene name) > Human
  • Add your favorite
  • CR2 (Gene name),
  • Complement receptor type 2 (Protein name ),  CR2_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    CR2(C3DR);
    Protein name:
    Complement receptor type 2(Cr2);
    Alternative:
    Epstein-Barr virus receptor(EBV receptor);Complement C3d receptor;CD21;
    CD:
    CD21;
    Organism:
    CR2 (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts (via Sushi domain 1 and 2) with C3dg.
    Function:
    Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1033
    Sequence:
    50:
    MGAAGLLGVF | LALVAPGVLG | ISCGSPPPIL | NGRISYYSTP | IAVGTVIRYS | 
    100:
    CSGTFRLIGE | KSLLCITKDK | VDGTWDKPAP | KCEYFNKYSS | CPEPIVPGGY | 
    150:
    KIRGSTPYRH | GDSVTFACKT | NFSMNGNKSV | WCQANNMWGP | TRLPTCVSVF | 
    200:
    PLECPALPMI | HNGHHTSENV | GSIAPGLSVT | YSCESGYLLV | GEKIINCLSS | 
    250:
    GKWSAVPPTC | EEARCKSLGR | FPNGKVKEPP | ILRVGVTANF | FCDEGYRLQG | 
    300:
    PPSSRCVIAG | QGVAWTKMPV | CEEIFCPSPP | PILNGRHIGN | SLANVSYGSI | 
    350:
    VTYTCDPDPE | EGVNFILIGE | STLRCTVDSQ | KTGTWSGPAP | RCELSTSAVQ | 
    400:
    CPHPQILRGR | MVSGQKDRYT | YNDTVIFACM | FGFTLKGSKQ | IRCNAQGTWE | 
    450:
    PSAPVCEKEC | QAPPNILNGQ | KEDRHMVRFD | PGTSIKYSCN | PGYVLVGEES | 
    500:
    IQCTSEGVWT | PPVPQCKVAA | CEATGRQLLT | KPQHQFVRPD | VNSSCGEGYK | 
    550:
    LSGSVYQECQ | GTIPWFMEIR | LCKEITCPPP | PVIYNGAHTG | SSLEDFPYGT | 
    600:
    TVTYTCNPGP | ERGVEFSLIG | ESTIRCTSND | QERGTWSGPA | PLCKLSLLAV | 
    650:
    QCSHVHIANG | YKISGKEAPY | FYNDTVTFKC | YSGFTLKGSS | QIRCKADNTW | 
    700:
    DPEIPVCEKE | TCQHVRQSLQ | ELPAGSRVEL | VNTSCQDGYQ | LTGHAYQMCQ | 
    750:
    DAENGIWFKK | IPLCKVIHCH | PPPVIVNGKH | TGMMAENFLY | GNEVSYECDQ | 
    800:
    GFYLLGEKKL | QCRSDSKGHG | SWSGPSPQCL | RSPPVTRCPN | PEVKHGYKLN | 
    850:
    KTHSAYSHND | IVYVDCNPGF | IMNGSRVIRC | HTDNTWVPGV | PTCIKKAFIG | 
    900:
    CPPPPKTPNG | NHTGGNIARF | SPGMSILYSC | DQGYLLVGEA | LLLCTHEGTW | 
    950:
    SQPAPHCKEV | NCSSPADMDG | IQKGLEPRKM | YQYGAVVTLE | CEDGYMLEGS | 
    1000:
    PQSQCQSDHQ | WNPPLAVCRS | RSLAPVLCGI | AAGLILLTFL | IVITLYVISK | 
    1033:
    HRARNYYTDT | SQKEAFHLEA | REVYSVDPYN | PAS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cr2
    Cat.:
    E0750h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Cr2
    Cat.:
    E0750m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Cr2
    Cat.:
    U0750h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cr2
    Cat.:
    U0750m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cr2
    Cat.:
    P0750Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cr2
    Cat.:
    P0750Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Cr2
    Monoclonal Antibody for Human Cr2
    Protein for Human Cr2
    Protein for Human Cr2

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor."
      Fujisaku A. , Harley J.B. , Frank M.B. , Gruner B.A. , Frazier B. , Holers V.M.
      J. Biol. Chem.264:2118-2125(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];VARIANT GLU-1003
    2. 2.
      "Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins."
      Weis J.J. , Toothaker L.E. , Smith J.A. , Weis J.H. , Fearon D.T.
      J. Exp. Med.167:1047-1066(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-993
      tissue: B-cell.
    3. 3.
      "Molecular cloning of the cDNA encoding the Epstein-Barr virus.C3d receptor (complement receptor type 2) of human b lymphocytes."
      Moore M. , Cooper N. , Tack B. , Nemerow G.
      Proc. Natl. Acad. Sci. U.S.A.84:9194-9198(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM C);VARIANT GLU-1003
    4. 4.
      "Evidence for a new transcript of the Epstein-Barr virus/C3d receptor (CR2, CD21) which is due to alternative exon usage."
      Barel M. , Balbo M. , Frade R.
      Mol. Immunol.35:1025-1031(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A; C AND D)
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM C)
      tissue: Synovium.
    6. 6.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM C)
      tissue: Spleen.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    8. 8.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A AND C);VARIANT ASN-639
      tissue: Lymph.
    10. 10.
      "Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement."
      Weis J.J. , Fearon D.T. , Klickstein L.B. , Wong W.W. , Richards S.A. , de Bruyn Kops A. , Smith J.A. , Weis J.H.
      Proc. Natl. Acad. Sci. U.S.A.83:5639-5643(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 226-233; 256-267; 332-341; 667-677 AND 898-908
    11. 11.
      "Characterization of the EBV/C3d receptor on the human Jurkat T cell line: evidence for a novel transcript."
      Sinha S.K. , Todd S.C. , Hedrick J.A. , Speiser C.L. , Lambris J.D. , Tsoukas C.D.
      J. Immunol.150:5311-5320(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 492-556 (ISOFORM B)
    12. 12.
      "Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein."
      Barel M. , Balbo M. , Gauffre A. , Frade R.
      Mol. Immunol.32:389-397(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A RECEPTOR FOR HNRPU
    13. 13.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-623
      tissue: Leukemic T-cell.
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CVID7
    15. 15.
      "Structure of complement receptor 2 in complex with its C3d ligand."
      Szakonyi G. , Guthridge J.M. , Li D. , Young K. , Holers V.M. , Chen X.S.
      Science292:1725-1728(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.04 ANGSTROMS) OF 21-153 IN COMPLEX WITH C3D;DISULFIDE BONDS
    16. 16.
      "The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding."
      Prota A.E. , Sage D.R. , Stehle T. , Fingeroth J.D.
      Proc. Natl. Acad. Sci. U.S.A.99:10641-10646(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 22-148;DISULFIDE BONDS;GLYCOSYLATION AT ASN-121 AND ASN-127
    17. 17.
      "The 15 SCR flexible extracellular domains of human complement receptor type 2 can mediate multiple ligand and antigen interactions."
      Gilbert H.E. , Asokan R. , Holers V.M. , Perkins S.J.
      J. Mol. Biol.362:1132-1147(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY SCATTERING SOLUTION STRUCTURE OF 21-971
    18. 18.
      "A crystal structure of the complex between human complement receptor 2 and its ligand C3d."
      van den Elsen J.M. , Isenman D.E.
      Science332:608-611(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.16 ANGSTROMS) OF 996-1303 IN COMPLEX WITH C3;INTERACTION WITH CR2;DISULFIDE BONDS;MUTAGENESIS OF ARG-103; ASP-112 AND LYS-128
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-639;INVOLVEMENT IN SLEB9
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Tumor necrosis Alpha Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter