Gene name:
C1sb(C1s;Gm5077);
Protein name:
Complement C1s-B subcomponent;
Alternative:
C1 esterase;Complement component 1 subcomponent s-B;
Organism:
Mouse (Mus musculus).
General annotation
Sub unit:
C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. Activated C1s is an disulfide-linked heterodimer of a heavy chain and a light chain.
Function:
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
Subcellular Location:
N/A
Protein attributes
50:
MWYLVLFSLL | ASFSAEPTMH | GEILSPNYPQ | AYPNDVVKSW | DIEVPEGFGI |
100:
HLYFTHVDIE | PSESCAYDSV | QIISGGIEEG | RLCGQRTSKS | PNSPIIEEFQ |
150:
FPYNKLQVVF | TSDFSIEEQF | TGFAAYYTAI | DVNECTDFTD | VPCSHFCNNF |
200:
IGGYFCSCPP | EYFLHDDMRN | CGVNCSGDVF | TALIGEISSP | NYPNPYPENS |
250:
RCEYQIQLQE | GFQVVVTMQR | EDFDVEPADS | EGNCPDSLTF | AAKNQQFGPY |
300:
CGDGFPGPLT | IRTQSNTLGI | VFQTDLMGQK | KGWKLRYHGD | PISCPKESTA |
350:
NSNWEPDKAK | YVFKDVVKIT | CVDGFEVVEG | HVSSTSYYST | CQSDGQWSNS |
400:
GLKCQPVYCG | IPDPIANGKV | EEPENSVFGT | VIHYTCEEPY | YYMEHEEGGE |
450:
YRCAANGRWV | NDQLGIELPR | CIPVCGVPTE | PFQVQQKIFG | GQPAKIENFP |
500:
WQVFFNHPTA | GGALINEYWV | LTAAHVVEKN | SDPSMYAGIT | ALRLADLENA |
550:
QRLYTKRVII | HPGWKEDDDL | NPRTNFDNDI | ALVQLKDPVK | MGPKFSPICL |
600:
PGTSSEYNLS | PGDMGLISGW | GRTEKRLHVI | NLRGAKVPVT | SLETCKQVKE |
650:
ENPTARPEDY | VITDNMICAG | EKGVDSCKGD | SGGAFAFQVP | NVKAPKFYVA |
688:
GLVSWGKKCG | AYGVYTKVKN | YVDWILKTMQ | ENSGPRKD
Vaild
Sequence:
Database Reference
Uniprot:
