Gene name:
CSNK2A2 (CK2A2) ;
Protein name:
Casein kinase II subunit alpha' (CK II alpha') ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
Function:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
Subcellular Location:
N/A
Protein Attributes:
50:
MPGPAAGSRA | RVYAEVNSLR | SREYWDYEAH | VPSWGNQDDY | QLVRKLGRGK |
100:
YSEVFEAINI | TNNERVVVKI | LKPVKKKKIK | REVKILENLR | GGTNIIKLID |
150:
TVKDPVSKTP | ALVFEYINNT | DFKQLYQILT | DFDIRFYMYE | LLKALDYCHS |
200:
KGIMHRDVKP | HNVMIDHQQK | KLRLIDWGLA | EFYHPAQEYN | VRVASRYFKG |
250:
PELLVDYQMY | DYSLDMWSLG | CMLASMIFRR | EPFFHGQDNY | DQLVRIAKVL |
300:
GTEELYGYLK | KYHIDLDPHF | NDILGQHSRK | RWENFIHSEN | RHLVSPEALD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Human CK II alpha'
ELISA Kit for Human CK II alpha'
ELISA Kit for Human CK II alpha'
CLIA Kit for Human CK II alpha'
CLIA Kit for Human CK II alpha'
CLIA Kit for Human CK II alpha'
Polyclonal Antibody for Human CK II alpha'
Polyclonal Antibody for Human CK II alpha'
Polyclonal Antibody for Human CK II alpha'
Monoclonal Antibody for Human CK II alpha'
Monoclonal Antibody for Human CK II alpha'
Monoclonal Antibody for Human CK II alpha'
Protein for Human CK II alpha'
Protein for Human CK II alpha'
Protein for Human CK II alpha'
R&D Technical Data
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12% SDS-PAGE analysis
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Ovary .
3.
"A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH SSRP1 AND SUPT16H
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN CELL CYCLE
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SSRP1 AND SUPT16H
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN APOPTOSIS
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18; SER-21 AND SER-288;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON STRUCTURE
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION IN REGULATION OF HSP90
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION IN WNT SIGNALING
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-13; SER-18; SER-21 AND SER-288;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : X-RAY CRYSTALLOGRAPHY (3.20 ANGSTROMS) OF 1-334 IN COMPLEX WITH INHIBITOR
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Cited for : X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS)
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more...
Nature446:153-158(2007)
[
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT [LARGE SCALE ANALYSIS] ALA-188