CSPG4 ELISA Kit for Human(Homo sapiens) | EIAab.comCSPG4 ELISA Kit for Human(Homo sapiens)

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CSPG4 (Gene name),

Chondroitin sulfate proteoglycan 4 (Protein name ), CSPG4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CSPG4(MCSP);

Protein name:

Chondroitin sulfate proteoglycan 4;

Alternative:

Melanoma chondroitin sulfate proteoglycan;Chondroitin sulfate proteoglycan NG2;Melanoma-associated chondroitin sulfate proteoglycan;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with the first PDZ domain of MPDZ. Interacts with PRKCA. Binds TNC, laminin-1, COL5A1 and COL6A2. Interacts with PLG and angiostatin. Binds FGF2 and PDGFA. Interacts with GRIP1, GRIP2 and GRIA2. Forms a ternary complex with GRIP1 and GRIA2 (By similarity). Interacts with LGALS3 and the integrin composed of ITGB1 and ITGA3. Interacts with ITGA4 through its chondroitin sulfate glycosaminoglycan. Interacts with BCAR1, CDC42 and ACK1. Interacts with MMP16.

Function:

Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.

Subcellular Location:

Apical cell membrane Single-pass type I membrane protein Extracellular side Cell projection lamellipodium membrane Single-pass type I membrane protein Extracellular side Localized at the apical plasma membrane it relocalizes to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Localizes to the retraction fibers. Localizes to the plasma membrane of oligodendrocytes.

Protein Attributes:

Sequence length:

2322

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2322:

DPELLQFCRT | PNPALKNGQY | WV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q6UVK1

MIM:

601172

UniGene:

Hs.513044

STRING:

9606.ENSP00000312506

SMR:

Q6UVK1

KEGG:

hsa:1464

Pfam:

PF02210

Uniprot:

Q6UVK1

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ELISA Kit for Human Chondroitin sulfate proteoglycan 4

Cat.:

E2136h

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Packing:

96T

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ELISA Kit for Human Chondroitin sulfate proteoglycan 4

Cat.:

E2136m

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Packing:

96T

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ELISA Kit for Human Chondroitin sulfate proteoglycan 4

Cat.:

E2136r

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Packing:

96T

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CLIA Kit for Human Chondroitin sulfate proteoglycan 4

Cat.:

U2136h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Chondroitin sulfate proteoglycan 4

Cat.:

U2136m

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MSDS:

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Packing:

96T

CLIA Kit for Human Chondroitin sulfate proteoglycan 4

Cat.:

U2136r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Chondroitin sulfate proteoglycan 4

Cat.:

P2136Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Chondroitin sulfate proteoglycan 4

Cat.:

P2136Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Chondroitin sulfate proteoglycan 4

Cat.:

P2136Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Chondroitin sulfate proteoglycan 4