CD55 ELISA Kit for Human(Homo sapiens) | EIAab.comCD55 ELISA Kit for Human(Homo sapiens)

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CD55 (Gene name),

Complement decay-accelerating factor (Protein name ), DAF_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

CD55(CR;DAF);

Protein name:

Complement decay-accelerating factor;

Alternative:

CD:

CD55;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer (major form) and non-disulfide-linked, covalent homodimer (minor form). Binds to coxsackievirus A21, coxsackieviruses B1, B3 and B5, human enterovirus 70, human echoviruses 6, 7, 11, 12, 20 and 21 capsid proteins and acts as a receptor for these viruses.

Function:

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

Subcellular Location:

Isoform 2 Cell membrane Lipid-anchor GPI-anchor

Protein Attributes:

Sequence length:

381

Sequence:

50:

100:

150:

200:

250:

300:

350:

381:

TTSGTTRLLS | GHTCFTLTGL | LGTLVTMGLL | T

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000316333

UniGene:

Hs.126517

KEGG:

hsa:1604

MIM:

125240

String:

P08174

SMR:

P08174

Pfam:

PF00084

Uniprot:

P08174

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ELISA Kit for Human Complement decay-accelerating factor

Cat.:

E0468h

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96T

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ELISA Kit for Human Complement decay-accelerating factor

Cat.:

E0468m

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Packing:

96T

CLIA Kit for Human Complement decay-accelerating factor

Cat.:

U0468h

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96T

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CLIA Kit for Human Complement decay-accelerating factor

Cat.:

U0468m

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Packing:

96T

Polyclonal Antibody for Human Complement decay-accelerating factor

Cat.:

P0468Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Complement decay-accelerating factor

Cat.:

P0468Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Complement decay-accelerating factor

Protein for Human Complement decay-accelerating factor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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Citations

[1].

"Effect of IL-6 and IL-8 on the expression of the complement activation inhibitors MAC-inhibitory protein and decay-accelerating factor in ovarian cancer A2780 cells"

Kapka-Skrzypczak L, Popek S, Sawicki K, et al.

From:Oncology Letters

References

1.

"Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins."
Caras I.W. , Davitz M.A. , Rhee L. , Weddell G. , Martin D.W. Jr. , Nussenzweig V.
Nature325:545-549(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
2.

"Molecular cloning and characterization of novel splicing variants of human decay-accelerating factor."
Osuka F. , Endo Y. , Higuchi M. , Suzuki H. , Shio Y. , Fujiu K. , Kanno R. , Oishi A. , Terashima M. , Fujita T. , Gotoh M.
Genomics88:316-322(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3; 4; 5; 6 AND 7);SUBCELLULAR LOCATION (ISOFORMS 3; 4; 5; 6 AND 7)
tissue: Lung.
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
4.

SeattleSNPs variation discovery resource
Submitted (2004-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT LEU-52
5.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Cervix.
8.

"Characterization of the decay-accelerating factor gene promoter region."
Ewulonu U.K. , Ravi L. , Medof M.E.
Proc. Natl. Acad. Sci. U.S.A.88:4675-4679(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-100
9.

"Cloning and characterization of cDNAs encoding the complete sequence of decay-accelerating factor of human complement."
Medof M.E. , Lublin D.M. , Holers V.M. , Ayers D.J. , Getty R.R. , Leykam J.F. , Atkinson J.P. , Tykocinski M.L.
Proc. Natl. Acad. Sci. U.S.A.84:2007-2011(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-381 (ISOFORM 2)
10.

"Decay-acceleration factor (DAF; CD 55) in the brain of Alzheimer's disease patients."
Kumar V.B. , Hyung C. , Nakra R. , Walters M. , Sasser T. , Bernardo A.
Submitted (1997-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 35-381 (ISOFORM 2)
tissue: Hippocampus.
11.

"Improved method for the isolation and preliminary characterization of human DAF (decay-accelerating factor)."
Sugita Y. , Negoro T. , Matsuda T. , Sakamoto T. , Tomita M.
J. Biochem.100:143-150(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-63
12.

"Isolation of two forms of decay-accelerating factor (DAF) from human urine."
Nakano Y. , Sugita Y. , Ishikawa Y. , Choi N.-H. , Tobe T. , Tomita M.
Biochim. Biophys. Acta1074:326-330(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-46
tissue: Urine.
13.

"Glycophospholipid membrane anchor attachment. Molecular analysis of the cleavage/attachment site."
Moran P. , Raab H. , Kohr W.J. , Caras I.W.
J. Biol. Chem.266:1250-1257(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR AT SER-353
14.

"Complete determination of disulfide bonds localized within the short consensus repeat units of decay accelerating factor (CD55 antigen)."
Nakano Y. , Sumida K. , Kikuta N. , Miura N.-H. , Tobe T. , Tomita M.
Biochim. Biophys. Acta1116:235-240(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS IN SUSHI DOMAINS
15.

"Decay-accelerating factor CD55 is identified as the receptor for echovirus 7 using CELICS, a rapid immuno-focal cloning method."
Ward T. , Pipkin P.A. , Clarkson N.A. , Stone D.M. , Minor P.D. , Almond J.W.
EMBO J.13:5070-5074(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS AN ECHOVIRUS RECEPTOR
16.

"Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses."
Bergelson J.M. , Chan M. , Solomon K.R. , St John N.F. , Lin H. , Finberg R.W.
Proc. Natl. Acad. Sci. U.S.A.91:6245-6248(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HUMAN ECHOVIRUSES 6/7/11/12/20/21 CAPSID PROTEINS
17.

"Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment."
Shafren D.R. , Bates R.C. , Agrez M.V. , Herd R.L. , Burns G.F. , Barry R.D.
J. Virol.69:3873-3877(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COXSACKIEVIRUSES B1/B3/B5 CAPSID PROTEINS
18.

"The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55)."
Karnauchow T.M. , Tolson D.L. , Harrison B.A. , Altman E. , Lublin D.M. , Dimock K.
J. Virol.70:5143-5152(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HUMAN ENTEROVIRUS 70 CAPSID PROTEINS
19.

"Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry."
Shafren D.R. , Dorahy D.J. , Ingham R.A. , Burns G.F. , Barry R.D.
J. Virol.71:4736-4743(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COXSACKIEVIRUS A21 CAPSID PROTEINS
20.

"Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins."
Elortza F. , Nuehse T.S. , Foster L.J. , Stensballe A. , Peck S.C. , Jensen O.N.
Mol. Cell. Proteomics2:1261-1270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
21.

"Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment."
Elortza F. , Mohammed S. , Bunkenborg J. , Foster L.J. , Nuehse T.S. , Brodbeck U. , Peck S.C. , Jensen O.N.
J. Proteome Res.5:935-943(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
22.

"Interaction of decay-accelerating factor with coxsackievirus B3."
Hafenstein S. , Bowman V.D. , Chipman P.R. , Bator Kelly C.M. , Lin F. , Medof M.E. , Rossmann M.G.
J. Virol.81:12927-12935(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COXSACKIEVIRUS B3 CAPSID PROTEINS
23.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-95
tissue: Liver.
24.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
25.

"Molecular basis of reduced or absent expression of decay-accelerating factor in Cromer blood group phenotypes."
Lublin D.M. , Mallinson G. , Poole J. , Reid M.E. , Thompson E.S. , Ferdman B.R. , Telen M.J. , Anstee D.J. , Tanner M.J.A.
Blood84:1276-1282(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BLOOD GROUP DR(A-) LEU-199
26.

"GUTI: a new antigen in the Cromer blood group system."
Storry J.R. , Sausais L. , Hue-Roye K. , Mudiwa F. , Ferrer Z. , Blajchman M.A. , Lublin D.M. , Ma B.W. , Miquel J.F. , Nervi F. , Pereira J. , Reid M.E.
Transfusion43:340-344(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BLOOD GROUP GUTI(-) HIS-240
27.

"Biochemical studies on red blood cells from a patient with the Inab phenotype (decay-accelerating factor deficiency)."
Reid M.E. , Mallinson G. , Sim R.B. , Poole J. , Pausch V. , Merry A.H. , Liew Y.W. , Tanner M.J.A.
Blood78:3291-3297(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN BLOOD GROUP INAB
28.

"Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A."
Williams P. , Chaudhry Y. , Goodfellow I.G. , Billington J. , Powell R. , Spiller O.B. , Evans D.J. , Lea S.
J. Biol. Chem.278:10691-10696(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 161-285
29.

"Complement regulation at the molecular level: the structure of decay-accelerating factor."
Lukacik P. , Roversi P. , White J. , Esser D. , Smith G.P. , Billington J. , Williams P.A. , Rudd P.M. , Wormald M.R. , Harvey D.J. , Crispin M.D. , Radcliffe C.M. , Dwek R.A. , Evans D.J. , Morgan B.P. , Smith R.A. , Lea S.M.
Proc. Natl. Acad. Sci. U.S.A.101:1279-1284(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF OF 35-286
30.

"Solution structure of a functionally active fragment of decay-accelerating factor."
Uhrinova S. , Lin F. , Ball G. , Bromek K. , Uhrin D. , Medof M.E. , Barlow P.N.
Proc. Natl. Acad. Sci. U.S.A.100:4718-4723(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 95-223

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