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Index > Protein center > AMD1(Gene name) > Human
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  • AMD1 (Gene name),
  • S-adenosylmethionine decarboxylase proenzyme (Protein name ),  DCAM_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AMD1(AMD);
    Protein name:
    S-adenosylmethionine decarboxylase proenzyme(AdoMetDC;SAMDC);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterotetramer of two alpha and two beta chains.
    Function:
    N/A
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    334
    Sequence:
    50:
    MEAAHFFEGT | EKLLEVWFSR | QQPDANQGSG | DLRTIPRSEW | DILLKDVQCS | 
    100:
    IISVTKTDKQ | EAYVLSESSM | FVSKRRFILK | TCGTTLLLKA | LVPLLKLARD | 
    150:
    YSGFDSIQSF | FYSRKNFMKP | SHQGYPHRNF | QEEIEFLNAI | FPNGAAYCMG | 
    200:
    RMNSDCWYLY | TLDFPESRVI | SQPDQTLEIL | MSELDPAVMD | QFYMKDGVTA | 
    250:
    KDVTRESGIR | DLIPGSVIDA | TMFNPCGYSM | NGMKSDGTYW | TIHITPEPEF | 
    300:
    SYVSFETNLS | QTSYDDLIRK | VVEVFKPGKF | VTTLFVNQSS | KCRTVLASPQ | 
    334:
    KIEGFKRLDC | QSAMFNDYNF | VFTSFAKKQQ | QQQS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    String:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human AdoMetDC
    Cat.:
    E0499h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human AdoMetDC
    Cat.:
    E0499b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human AdoMetDC
    Cat.:
    E0499m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human AdoMetDC
    Cat.:
    E0499r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AdoMetDC
    Cat.:
    U0499m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AdoMetDC
    Cat.:
    U0499b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AdoMetDC
    Cat.:
    U0499h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AdoMetDC
    Cat.:
    U0499r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human AdoMetDC
    Cat.:
    P0499Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AdoMetDC
    Cat.:
    P0499Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AdoMetDC
    Polyclonal Antibody for Human AdoMetDC
    Cat.:
    P0499Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human AdoMetDC
    Monoclonal Antibody for Human AdoMetDC
    Monoclonal Antibody for Human AdoMetDC
    Monoclonal Antibody for Human AdoMetDC
    Protein for Human AdoMetDC
    Protein for Human AdoMetDC
    Protein for Human AdoMetDC
    Protein for Human AdoMetDC

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    Precision
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    Linearity
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    References
    1. 1.
      "Structure and regulation of mammalian S-adenosylmethionine decarboxylase."
      Pajunen A. , Crozat A. , Jaenne O.A. , Ihalainen R. , Laitinen P.H. , Stanley B. , Madhubala R. , Pegg A.E.
      J. Biol. Chem.263:17040-17049(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;PYRUVATE FORMATION AT SER-68
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Heart.
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    6. 6.
      "Amino acid residues necessary for putrescine stimulation of human S-adenosylmethionine decarboxylase proenzyme processing and catalytic activity."
      Stanley B.A. , Pegg A.E.
      J. Biol. Chem.266:18502-18506(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS
    7. 7.
      "Mechanistic studies of the processing of human S-adenosylmethionine decarboxylase proenzyme. Isolation of an ester intermediate."
      Xiong H. , Pegg A.E.
      J. Biol. Chem.274:35059-35066(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF SER-229 AND HIS-243
    8. 8.
      "Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase."
      Xiong H. , Stanley B.A. , Pegg A.E.
      Biochemistry38:2462-2470(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IMPORTANCE OF CYS-82 IN CATALYTIC ACTIVITY;INHIBITION BY IODOACETIC ACID
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-298;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "The crystal structure of human S-adenosylmethionine decarboxylase at 2.25-A resolution reveals a novel fold."
      Ekstrom J.L. , Mathews I.I. , Stanley B.A. , Pegg A.E. , Ealick S.E.
      Structure7:583-595(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS)
    11. 11.
      "The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase."
      Tolbert W.D. , Ekstrom J.L. , Mathews I.I. , Secrist J.A. III , Kapoor P. , Pegg A.E. , Ealick S.E.
      Biochemistry40:9484-9494(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS);REACTION MECHANISM;MUTAGENESIS OF PHE-7 AND PHE-223
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