Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > DDR1(Gene name) > Human
  • Add your favorite
  • DDR1 (Gene name),
  • Epithelial discoidin domain-containing receptor 1 (Protein name ),  DDR1_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    DDR1(CAK;EDDR1;NEP;NTRK4;PTK3A;RTK6;TRKE);
    Protein name:
    Epithelial discoidin domain-containing receptor 1(Epithelial discoidin domain receptor 1);
    Alternative:
    Tyrosine-protein kinase CAK;Cell adhesion kinase;CD167 antigen-like family member A;HGK2;Discoidin receptor tyrosine kinase;Protein-tyrosine kinase 3A;Mammary carcinoma kinase 10(MCK-10);TRK E;Protein-tyrosine kinase RTK-6;Tyrosine kinase DDR;
    CD:
    CD167a;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts (via PPxY motif) with WWC1 (via WW domains) in a collagen-regulated manner. Forms a tripartite complex with WWC1 and PRKCZ, but predominantly in the absence of collagen.
    Function:
    May be involved in cell-cell interactions and recognition.
    Subcellular Location:
    Isoform 4 Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    913
    Sequence:
    50:
    MGPEALSSLL | LLLLVASGDA | DMKGHFDPAK | CRYALGMQDR | TIPDSDISAS | 
    100:
    SSWSDSTAAR | HSRLESSDGD | GAWCPAGSVF | PKEEEYLQVD | LQRLHLVALV | 
    150:
    GTQGRHAGGL | GKEFSRSYRL | RYSRDGRRWM | GWKDRWGQEV | ISGNEDPEGV | 
    200:
    VLKDLGPPMV | ARLVRFYPRA | DRVMSVCLRV | ELYGCLWRDG | LLSYTAPVGQ | 
    250:
    TMYLSEAVYL | NDSTYDGHTV | GGLQYGGLGQ | LADGVVGLDD | FRKSQELRVW | 
    300:
    PGYDYVGWSN | HSFSSGYVEM | EFEFDRLRAF | QAMQVHCNNM | HTLGARLPGG | 
    350:
    VECRFRRGPA | MAWEGEPMRH | NLGGNLGDPR | ARAVSVPLGG | RVARFLQCRF | 
    400:
    LFAGPWLLFS | EISFISDVVN | NSSPALGGTF | PPAPWWPPGP | PPTNFSSLEL | 
    450:
    EPRGQQPVAK | AEGSPTAILI | GCLVAIILLL | LLIIALMLWR | LHWRRLLSKA | 
    500:
    ERRVLEEELT | VHLSVPGDTI | LINNRPGPRE | PPPYQEPRPR | GNPPHSAPCV | 
    550:
    PNGSALLLSN | PAYRLLLATY | ARPPRGPGPP | TPAWAKPTNT | QAYSGDYMEP | 
    600:
    EKPGAPLLPP | PPQNSVPHYA | EADIVTLQGV | TGGNTYAVPA | LPPGAVGDGP | 
    650:
    PRVDFPRSRL | RFKEKLGEGQ | FGEVHLCEVD | SPQDLVSLDF | PLNVRKGHPL | 
    700:
    LVAVKILRPD | ATKNARNDFL | KEVKIMSRLK | DPNIIRLLGV | CVQDDPLCMI | 
    750:
    TDYMENGDLN | QFLSAHQLED | KAAEGAPGDG | QAAQGPTISY | PMLLHVAAQI | 
    800:
    ASGMRYLATL | NFVHRDLATR | NCLVGENFTI | KIADFGMSRN | LYAGDYYRVQ | 
    850:
    GRAVLPIRWM | AWECILMGKF | TTASDVWAFG | VTLWEVLMLC | RAQPFGQLTD | 
    900:
    EQVIENAGEF | FRDQGRQVYL | SRPPACPQGL | YELMLRCWSR | ESEQRPPFSQ | 
    913:
    LHRFLAEDAL | NTV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    SMR:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Epithelial discoidin domain receptor 1
    Cat.:
    E15103h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Epithelial discoidin domain receptor 1
    MSDS:
    Please sign in first.
    ELISA Kit for Human Epithelial discoidin domain receptor 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Epithelial discoidin domain receptor 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Epithelial discoidin domain receptor 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Epithelial discoidin domain receptor 1
    Cat.:
    U15103h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Epithelial discoidin domain receptor 1
    Polyclonal Antibody for Human Epithelial discoidin domain receptor 1
    Polyclonal Antibody for Human Epithelial discoidin domain receptor 1
    Monoclonal Antibody for Human Epithelial discoidin domain receptor 1
    Monoclonal Antibody for Human Epithelial discoidin domain receptor 1
    Monoclonal Antibody for Human Epithelial discoidin domain receptor 1
    Protein for Human Epithelial discoidin domain receptor 1
    Protein for Human Epithelial discoidin domain receptor 1
    Protein for Human Epithelial discoidin domain receptor 1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues."
      di Marco E. , Cutuli N. , Guerra L. , Cancedda R. , de Luca M.
      J. Biol. Chem.268:24290-24295(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Brain.
      tissue: Keratinocyte.
    2. 2.
      "A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain."
      Johnson J.D. , Edman J.C. , Rutter W.J.
      Proc. Natl. Acad. Sci. U.S.A.90:5677-5681(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT VAL-833
      tissue: Placenta.
    3. 3.
      "Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line."
      Laval S. , Butler R. , Shelling A.N. , Hanby A.M. , Poulsom R. , Ganesan T.S.
      Cell Growth Differ.5:1173-1183(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
      tissue: Ovary.
    4. 4.
      "Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain."
      Perez J.L. , Shen X. , Finkernagel S. , Sciorra L. , Jenkins N.A. , Gilbert D.J. , Copeland N.G. , Wong T.W.
      Oncogene9:211-219(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Fetal liver.
    5. 5.
      "Receptor protein tyrosine kinase DDR is up-regulated by p53 protein."
      Sakuma S. , Tada M. , Saya H. , Sawamura Y. , Shinohe Y. , Abe H.
      FEBS Lett.398:165-169(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-833
    6. 6.
      "The genomic structure of discoidin receptor tyrosine kinase."
      Playford M.P. , Butler R.J. , Wang X.C. , Katso R.M. , Cooke I.E. , Ganesan T.S.
      Genome Res.6:620-627(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines."
      Perez J.L. , Jing S.Q. , Wong T.W.
      Oncogene12:1469-1477(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Lung.
    8. 8.
      "Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis."
      Jin P. , Zhang J. , Sumariwalla P.F. , Ni I. , Jorgensen B. , Crawford D. , Phillips S. , Feldmann M. , Shepard H.M. , Paleolog E.M.
      Arthritis Res. Ther.10:R73-R73(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [MRNA] OF 1-286 (ISOFORMS 1/2/4)
    9. 9.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 5)
      tissue: Brain.
      tissue: Placenta.
    10. 10.
      "Preparation of a set of expression-ready clones of mammalian long cDNAs encoding large proteins by the ORF trap cloning method."
      Nakajima D. , Saito K. , Yamakawa H. , Kikuno R.F. , Nakayama M. , Ohara R. , Okazaki N. , Koga H. , Nagase T. , Ohara O.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    11. 11.
      "Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity."
      Shiina T. , Ota M. , Shimizu S. , Katsuyama Y. , Hashimoto N. , Takasu M. , Anzai T. , Kulski J.K. , Kikkawa E. , Naruse T. , Kimura N. , Yanagiya K. , Watanabe A. , Hosomichi K. , Kohara S. , Iwamoto C. , Umehara Y. , Meyer A. , more...
      Genetics173:1555-1570(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      tissue: Peripheral blood leukocyte.
    12. 12.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    14. 14.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
      tissue: Muscle.
    15. 15.
      "Glycosylation at Asn211 regulates the activation state of the discoidin domain receptor 1 (DDR1)."
      Fu H.L. , Valiathan R.R. , Payne L. , Kumarasiri M. , Mahasenan K.V. , Mobashery S. , Huang P. , Fridman R.
      J. Biol. Chem.289:9275-9287(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 480-490; 515-525 AND 790-798;IDENTIFICATION BY MASS SPECTROMETRY;SUBUNIT;SUBCELLULAR LOCATION;PHOSPHORYLATION AT TYR-484; TYR-513; TYR-520; TYR-792; TYR-796 AND TYR-797;GLYCOSYLATION AT ASN-211 AND ASN-260;MUTAGENESIS OF ARG-105; ASN-211; SER-213; ASN-260; ASN-371; THR-379; THR-393; ASN-394 AND LYS-655
    16. 16.
      "Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer."
      Alves F. , Vogel W. , Mossie K. , Millauer B. , Hoefler H. , Ullrich A.
      Oncogene10:609-618(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 501-550 (ISOFORMS 1/4);NUCLEOTIDE SEQUENCE [MRNA] OF 501-550 AND 651-694 (ISOFORM 2);NUCLEOTIDE SEQUENCE [MRNA] OF 651-694 (ISOFORM 4);ALTERNATIVE SPLICING;TISSUE SPECIFICITY
      tissue: Mammary carcinoma.
    17. 17.
      "Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors."
      Weiner T.M. , Liu E.T. , Craven R.J. , Cance W.G.
      Ann. Surg. Oncol.1:18-27(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 771-824 (ISOFORMS 1/2/4)
    18. 18.
      "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes."
      Lee S.-T. , Strunk K.M. , Spritz R.A.
      Oncogene8:3403-3410(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 772-823 (ISOFORMS 1/2/4);TISSUE SPECIFICITY
      tissue: Melanocyte.
    19. 19.
      "The discoidin domain receptor tyrosine kinases are activated by collagen."
      Vogel W. , Gish G.D. , Alves F. , Pawson T.
      Mol. Cell1:13-23(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS COLLAGEN RECEPTOR;PHOSPHORYLATION AT TYR-513;INTERACTION WITH SHC1;AUTOPHOSPHORYLATION;SUBCELLULAR LOCATION
    20. 20.
      "Tyrosine kinase activity of discoidin domain receptor 1 is necessary for smooth muscle cell migration and matrix metalloproteinase expression."
      Hou G. , Vogel W.F. , Bendeck M.P.
      Circ. Res.90:1147-1149(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    21. 21.
      "Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1."
      Koo D.H. , McFadden C. , Huang Y. , Abdulhussein R. , Friese-Hamim M. , Vogel W.F.
      FEBS Lett.580:15-22(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PTPN11 AND NCK2;PHOSPHORYLATION AT TYR-740;MUTAGENESIS OF TYR-740
    22. 22.
      "Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2."
      Ram R. , Lorente G. , Nikolich K. , Urfer R. , Foehr E. , Nagavarapu U.
      J. Neurooncol.76:239-248(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    23. 23.
      "KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling."
      Hilton H.N. , Stanford P.M. , Harris J. , Oakes S.R. , Kaplan W. , Daly R.J. , Ormandy C.J.
      Biochim. Biophys. Acta1783:383-393(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH WWC1 AND PRKCZ
    24. 24.
      "The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA."
      Huang Y. , Arora P. , McCulloch C.A. , Vogel W.F.
      J. Cell Sci.122:1637-1646(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;AUTOPHOSPHORYLATION;INTERACTION WITH MYH9
    25. 25.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-631;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    26. 26.
      "DDR1 regulates the stabilization of cell surface E-cadherin and E-cadherin-mediated cell aggregation."
      Eswaramoorthy R. , Wang C.K. , Chen W.C. , Tang M.J. , Ho M.L. , Hwang C.C. , Wang H.M. , Wang C.Z.
      J. Cell. Physiol.224:387-397(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CDH1
    27. 27.
      "Collagen stimulates discoidin domain receptor 1-mediated migration of smooth muscle cells through Src."
      Lu K.K. , Trcka D. , Bendeck M.P.
      Cardiovasc. Pathol.20:71-76(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SRC
    28. 28.
      "Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production."
      Roberts M.E. , Magowan L. , Hall I.P. , Johnson S.R.
      Eur. Respir. J.37:1482-1493(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    29. 29.
      "Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1."
      Xu H. , Raynal N. , Stathopoulos S. , Myllyharju J. , Farndale R.W. , Leitinger B.
      Matrix Biol.30:16-26(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS COLLAGEN RECEPTOR;AUTOPHOSPHORYLATION
    30. 30.
      "Structure of the discoidin domain receptor 1 extracellular region bound to an inhibitory Fab fragment reveals features important for signaling."
      Carafoli F. , Mayer M.C. , Shiraishi K. , Pecheva M.A. , Chan L.Y. , Nan R. , Leitinger B. , Hohenester E.
      Structure20:688-697(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 29-367 IN COMPLEX WITH INHIBITORY ANTIBODY;SUBUNIT;CALCIUM-BINDING SITES;GLYCOSYLATION AT ASN-211 AND ASN-260;DISULFIDE BONDS
    31. 31.
      "Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor."
      Kim H.G. , Tan L. , Weisberg E.L. , Liu F. , Canning P. , Choi H.G. , Ezell S.A. , Wu H. , Zhao Z. , Wang J. , Mandinova A. , Griffin J.D. , Bullock A.N. , Liu Q. , Lee S.W. , Gray N.S.
      ACS Chem. Biol.8:2145-2150(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 601-913 IN COMPLEX WITH INHIBITOR;AUTOPHOSPHORYLATION;MUTAGENESIS OF GLY-707
    32. 32.
      "Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors."
      Canning P. , Tan L. , Chu K. , Lee S.W. , Gray N.S. , Bullock A.N.
      J. Mol. Biol.426:2457-2470(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 601-913 IN COMPLEXES WITH INHIBITORS IMATINIB AND PONATINIB;ENZYME REGULATION;AUTOPHOSPHORYLATION
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a KSR2 Gdf5
    Top Searches
    Ubiquitin-protein ligase Ubiquitin ELISA metalloproteinase Tumor necrosis Asprosin TRAP1A Alpha
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    Twitter