Protein name:
Dihydropteridine reductase ;
Alternative:
Quinoid dihydropteridine reductase ;HDHPR ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases.
Subcellular Location:
N/A
Protein Attributes:
50:
MAAAAAAGEA | RRVLVYGGRG | ALGSRCVQAF | RARNWWVASV | DVVENEEASA |
100:
SIIVKMTDSF | TEQADQVTAE | VGKLLGEEKV | DAILCVAGGW | AGGNAKSKSL |
150:
FKNCDLMWKQ | SIWTSTISSH | LATKHLKEGG | LLTLAGAKAA | LDGTPGMIGY |
200:
GMAKGAVHQL | CQSLAGKNSG | MPPGAAAIAV | LPVTLDTPMN | RKSMPEADFS |
244:
SWTPLEFLVE | TFHDWITGKN | RPSSGSLIQV | VTTEGRTELT | PAYF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Mouse
Pig
ELISA Kit for Human Dihydropteridine reductase
ELISA Kit for Human Dihydropteridine reductase
ELISA Kit for Human Dihydropteridine reductase
ELISA Kit for Human Dihydropteridine reductase
ELISA Kit for Human Dihydropteridine reductase
CLIA Kit for Human Dihydropteridine reductase
CLIA Kit for Human Dihydropteridine reductase
CLIA Kit for Human Dihydropteridine reductase
CLIA Kit for Human Dihydropteridine reductase
CLIA Kit for Human Dihydropteridine reductase
Polyclonal Antibody for Human Dihydropteridine reductase
Polyclonal Antibody for Human Dihydropteridine reductase
Polyclonal Antibody for Human Dihydropteridine reductase
Polyclonal Antibody for Human Dihydropteridine reductase
Polyclonal Antibody for Human Dihydropteridine reductase
Monoclonal Antibody for Human Dihydropteridine reductase
Monoclonal Antibody for Human Dihydropteridine reductase
Monoclonal Antibody for Human Dihydropteridine reductase
Monoclonal Antibody for Human Dihydropteridine reductase
Monoclonal Antibody for Human Dihydropteridine reductase
Protein for Human Dihydropteridine reductase
Protein for Human Dihydropteridine reductase
Protein for Human Dihydropteridine reductase
Protein for Human Dihydropteridine reductase
Protein for Human Dihydropteridine reductase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT THR-51
2.
Dahl H.-H.M.
Submitted (1987-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION TO 51
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT THR-51
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"Dihydropteridine reductase deficiency: physical structure of the QDPR gene, identification of two new mutations and genotype-phenotype correlations."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-51;VARIANTS HPABH4C ASP-23; CYS-150; TYR-158 AND ILE-THR-GLY-218 INS
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Nat. Genet.36:40-45(2004)
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[
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Cerebellum .
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-11 AND 128-138;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Colon carcinoma .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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,
Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
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PubMed ]
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Europe PMC ]
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Abstract ]
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Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.
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Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS)
17.
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Cited for : REVIEW ON VARIANTS
18.
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Cited for : VARIANTS HPABH4C ASP-23 AND GLY-108
19.
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Cited for : VARIANT HPABH4C THR-123 INS
20.
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Cited for : VARIANTS HPABH4C PRO-14 AND VAL-17
21.
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Cited for : VARIANTS HPABH4C ARG-17; ASP-18; ASP-23; ARG-66; ARG-149 AND CYS-150