D(2) dopamine receptor (Protein name
), DRD2_HUMAN from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Related Databases
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Gene name:
DRD2;
Protein name:
D(2) dopamine receptor;
Alternative:
Dopamine D2 receptor;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Forms homo- and heterooligomers with DRD4. The interaction with DRD4 may modulate agonist-induced downstream signaling. Interacts with GPRASP1, PPP1R9B and CLIC6 (By similarity). Interacts with CADPS and CADPS2. Interacts with ARRB2 (By similarity). Interacts with GNAI1.
Function:
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
Monoclonal Antibody for Human D(2) dopamine receptor
Monoclonal Antibody for Human D(2) dopamine receptor
Monoclonal Antibody for Human D(2) dopamine receptor
Monoclonal Antibody for Human D(2) dopamine receptor
Monoclonal Antibody for Human D(2) dopamine receptor
Protein for Human D(2) dopamine receptor
Protein for Human D(2) dopamine receptor
Protein for Human D(2) dopamine receptor
Protein for Human D(2) dopamine receptor
Protein for Human D(2) dopamine receptor
R&D Technical Data
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s
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s
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Precision
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Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤7.9%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤10.8%
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Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤3.9%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤7.7%
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Recovery
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Recovery was determined by spiking various levels of DRD2 into serum and plasma .
Sample Type
Average(%)
Recovery Range(%)
Serum
101
94-107
Plasma
100
92-106
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Recovery was determined by spiking various levels of ACE into serum and plasma .
Sample Type
Average(%)
Recovery Range(%)
Serum
99
91-103
Plasma
98
93-106
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Linearity
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The linearity of the kit was assayed by testing samples spiked with appropriate concentration of DRD2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Sample
1:2
1:4
1:8
1:16
serum(n=5)
94-108%
96-107%
93-110%
97-104%
EDTA plasma(n=5)
92-108%
91-110%
92-106%
94-108%
heparin plasma(n=5)
95-106%
93-107%
95-105%
91-109%
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The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Sample
1:2
1:4
1:8
1:16
serum(n=5)
92-105%
90-101%
95-105%
92-109%
EDTA plasma(n=5)
89-95%
93105%
89-94%
90-106%
heparin plasma(n=5)
93-104%
94-110%
101-111%
91-110%
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: INTERACTION WITH HTR2A;FUNCTION;SUBCELLULAR LOCATION
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 208-226 IN COMPLEX WITH GNAI1;INTERACTION WITH GNAI1;FUNCTION