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Index > Protein center > DSG1(Gene name) > Human
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  • DSG1 (Gene name),
  • Desmoglein-1 (Protein name ),  DSG1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    DSG1(CDHF4);
    Protein name:
    Desmoglein-1;
    Alternative:
    Desmosomal glycoprotein 1(DG1;DGI);Cadherin family member 4;Pemphigus foliaceus antigen;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Cell junction desmosome
    Protein Attributes:
    Sequence length:
    1049
    Sequence:
    50:
    MDWSFFRVVA | MLFIFLVVVE | VNSEFRIQVR | DYNTKNGTIK | WHSIRRQKRE | 
    100:
    WIKFAAACRE | GEDNSKRNPI | AKIHSDCAAN | QQVTYRISGV | GIDQPPYGIF | 
    150:
    VINQKTGEIN | ITSIVDREVT | PFFIIYCRAL | NSMGQDLERP | LELRVRVLDI | 
    200:
    NDNPPVFSMA | TFAGQIEENS | NANTLVMILN | ATDADEPNNL | NSKIAFKIIR | 
    250:
    QEPSDSPMFI | INRNTGEIRT | MNNFLDREQY | GQYALAVRGS | DRDGGADGMS | 
    300:
    AECECNIKIL | DVNDNIPYME | QSSYTIEIQE | NTLNSNLLEI | RVIDLDEEFS | 
    350:
    ANWMAVIFFI | SGNEGNWFEI | EMNERTNVGI | LKVVKPLDYE | AMQSLQLSIG | 
    400:
    VRNKAEFHHS | IMSQYKLKAS | AISVTVLNVI | EGPVFRPGSK | TYVVTGNMGS | 
    450:
    NDKVGDFVAT | DLDTGRPSTT | VRYVMGNNPA | DLLAVDSRTG | KLTLKNKVTK | 
    500:
    EQYNMLGGKY | QGTILSIDDN | LQRTCTGTIN | INIQSFGNDD | RTNTEPNTKI | 
    550:
    TTNTGRQEST | SSTNYDTSTT | STDSSQVYSS | EPGNGAKDLL | SDNVHFGPAG | 
    600:
    IGLLIMGFLV | LGLVPFLMIC | CDCGGAPRSA | AGFEPVPECS | DGAIHSWAVE | 
    650:
    GPQPEPRDIT | TVIPQIPPDN | ANIIECIDNS | GVYTNEYGGR | EMQDLGGGER | 
    700:
    MTGFELTEGV | KTSGMPEICQ | EYSGTLRRNS | MRECREGGLN | MNFMESYFCQ | 
    750:
    KAYAYADEDE | GRPSNDCLLI | YDIEGVGSPA | GSVGCCSFIG | EDLDDSFLDT | 
    800:
    LGPKFKKLAD | ISLGKESYPD | LDPSWPPQST | EPVCLPQETE | PVVSGHPPIS | 
    850:
    PHFGTTTVIS | ESTYPSGPGV | LHPKPILDPL | GYGNVTVTES | YTTSDTLKPS | 
    900:
    VHVHDNRPAS | NVVVTERVVG | PISGADLHGM | LEMPDLRDGS | NVIVTERVIA | 
    950:
    PSSSLPTSLT | IHHPRESSNV | VVTERVIQPT | SGMIGSLSMH | PELANAHNVI | 
    1000:
    VTERVVSGAG | VTGISGTTGI | SGGIGSSGLV | GTSMGAGSGA | LSGAGISGGG | 
    1049:
    IGLSSLGGTA | SIGHMRSSSD | HHFNQTIGSA | SPSTARSRIT | KYSTVQYSK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    SMR:
    KEGG:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Desmoglein-1
    Cat.:
    E0729h
    Price:
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    Packing:
    96T
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    ELISA Kit for Human Desmoglein-1
    Cat.:
    E0729d
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    Packing:
    96T
    ELISA Kit for Human Desmoglein-1
    Cat.:
    E0729p
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    Packing:
    96T
    ELISA Kit for Human Desmoglein-1
    Cat.:
    E0729b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Desmoglein-1
    Cat.:
    U0729p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Desmoglein-1
    Cat.:
    U0729h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Desmoglein-1
    Cat.:
    U0729d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Desmoglein-1
    Cat.:
    U0729b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Desmoglein-1
    Polyclonal Antibody for Human Desmoglein-1
    Polyclonal Antibody for Human Desmoglein-1
    Polyclonal Antibody for Human Desmoglein-1
    Cat.:
    P0729Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Desmoglein-1
    Monoclonal Antibody for Human Desmoglein-1
    Monoclonal Antibody for Human Desmoglein-1
    Monoclonal Antibody for Human Desmoglein-1
    Protein for Human Desmoglein-1
    Protein for Human Desmoglein-1
    Protein for Human Desmoglein-1
    Protein for Human Desmoglein-1

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    References
    1. 1.
      "Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules."
      Wheeler G.N. , Parker A.E. , Thomas C.L. , Ataliotis P. , Poynter D. , Arnemann J. , Rutman A.J. , Pidsley S.C. , Watt F.M. , Rees D.A. , Buxton R.S. , Magee A.I.
      Proc. Natl. Acad. Sci. U.S.A.88:4796-4800(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT VAL-11
      tissue: Keratinocyte.
    2. 2.
      "Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome."
      Nilles L.A. , Parry D.A. , Powers E.E. , Angst B.D. , Wagner R.M. , Green K.J.
      J. Cell Sci.99:809-821(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT VAL-11
      tissue: Foreskin.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Testis.
    4. 5.
      "N-terminal deletion in a desmosomal cadherin causes the autosomal dominant skin disease striate palmoplantar keratoderma."
      Rickman L. , Simrak D. , Stevens H.P. , Hunt D.M. , King I.A. , Bryant S.P. , Eady R.A.J. , Leigh I.M. , Arnemann J. , Magee A.I. , Kelsell D.P. , Buxton R.S.
      Hum. Mol. Genet.8:971-976(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PPKS1
    5. 6.
      "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
      Ramachandran P. , Boontheung P. , Xie Y. , Sondej M. , Wong D.T. , Loo J.A.
      J. Proteome Res.5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-110
      tissue: Saliva.
    6. 7.
      "Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes."
      Choi H.J. , Gross J.C. , Pokutta S. , Weis W.I.
      J. Biol. Chem.284:31776-31788(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH JUP/PLAKOGLOBIN
    7. 8.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-579;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN EPKHE
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