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Index > Protein center > ADAR(Gene name) > Human
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  • ADAR (Gene name),
  • Double-stranded RNA-specific adenosine deaminase (Protein name ),  DSRAD_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    ADAR(ADAR1;DSRAD;G1P1;IFI4);
    Protein name:
    Double-stranded RNA-specific adenosine deaminase(DRADA);
    Alternative:
    Interferon-inducible protein 4(IFI-4);136 kDa double-stranded RNA-binding protein(p136);K88DSRBP;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Isoform 1 interacts with ILF2/NF45 and ILF3/NF90.
    Function:
    Converts multiple adenosines to inosines and creates I/U mismatched base pairs in double-helical RNA substrates without apparent sequence specificity. Has been found to modify more frequently adenosines in AU-rich regions, probably due to the relative ease of melting A/U base pairs as compared to G/C pairs. Functions to modify viral RNA genomes and may be responsible for hypermutation of certain negative-stranded viruses. Edits the messenger RNAs for glutamate receptor (GLUR) subunits by site-selective adenosine deamination. Produces low-level editing at the GLUR-B Q/R site, but edits efficiently at the R/G site and HOTSPOT1. Binds to short interfering RNAs (siRNA) without editing them and suppresses siRNA-mediated RNA interference. Binds to ILF3/NF90 and up-regulates ILF3-mediated gene expression.
    Subcellular Location:
    Cytoplasm Nucleus nucleolus Isoform 1 is found predominantly in cytoplasm but appears to shuttle between the cytoplasm and nucleus. Isoform 5 is found exclusively in the nucleolus.
    Protein Attributes:
    Sequence length:
    1226
    Sequence:
    50:
    MNPRQGYSLS | GYYTHPFQGY | EHRQLRYQQP | GPGSSPSSFL | LKQIEFLKGQ | 
    100:
    LPEAPVIGKQ | TPSLPPSLPG | LRPRFPVLLA | SSTRGRQVDI | RGVPRGVHLR | 
    150:
    SQGLQRGFQH | PSPRGRSLPQ | RGVDCLSSHF | QELSIYQDQE | QRILKFLEEL | 
    200:
    GEGKATTAHD | LSGKLGTPKK | EINRVLYSLA | KKGKLQKEAG | TPPLWKIAVS | 
    250:
    TQAWNQHSGV | VRPDGHSQGA | PNSDPSLEPE | DRNSTSVSED | LLEPFIAVSA | 
    300:
    QAWNQHSGVV | RPDSHSQGSP | NSDPGLEPED | SNSTSALEDP | LEFLDMAEIK | 
    350:
    EKICDYLFNV | SDSSALNLAK | NIGLTKARDI | NAVLIDMERQ | GDVYRQGTTP | 
    400:
    PIWHLTDKKR | ERMQIKRNTN | SVPETAPAAI | PETKRNAEFL | TCNIPTSNAS | 
    450:
    NNMVTTEKVE | NGQEPVIKLE | NRQEARPEPA | RLKPPVHYNG | PSKAGYVDFE | 
    500:
    NGQWATDDIP | DDLNSIRAAP | GEFRAIMEMP | SFYSHGLPRC | SPYKKLTECQ | 
    550:
    LKNPISGLLE | YAQFASQTCE | FNMIEQSGPP | HEPRFKFQVV | INGREFPPAE | 
    600:
    AGSKKVAKQD | AAMKAMTILL | EEAKAKDSGK | SEESSHYSTE | KESEKTAESQ | 
    650:
    TPTPSATSFF | SGKSPVTTLL | ECMHKLGNSC | EFRLLSKEGP | AHEPKFQYCV | 
    700:
    AVGAQTFPSV | SAPSKKVAKQ | MAAEEAMKAL | HGEATNSMAS | DNQPEGMISE | 
    750:
    SLDNLESMMP | NKVRKIGELV | RYLNTNPVGG | LLEYARSHGF | AAEFKLVDQS | 
    800:
    GPPHEPKFVY | QAKVGGRWFP | AVCAHSKKQG | KQEAADAALR | VLIGENEKAE | 
    850:
    RMGFTEVTPV | TGASLRRTML | LLSRSPEAQP | KTLPLTGSTF | HDQIAMLSHR | 
    900:
    CFNTLTNSFQ | PSLLGRKILA | AIIMKKDSED | MGVVVSLGTG | NRCVKGDSLS | 
    950:
    LKGETVNDCH | AEIISRRGFI | RFLYSELMKY | NSQTAKDSIF | EPAKGGEKLQ | 
    1000:
    IKKTVSFHLY | ISTAPCGDGA | LFDKSCSDRA | MESTESRHYP | VFENPKQGKL | 
    1050:
    RTKVENGEGT | IPVESSDIVP | TWDGIRLGER | LRTMSCSDKI | LRWNVLGLQG | 
    1100:
    ALLTHFLQPI | YLKSVTLGYL | FSQGHLTRAI | CCRVTRDGSA | FEDGLRHPFI | 
    1150:
    VNHPKVGRVS | IYDSKRQSGK | TKETSVNWCL | ADGYDLEILD | GTRGTVDGPR | 
    1200:
    NELSRVSKKN | IFLLFKKLCS | FRYRRDLLRL | SYGEAKKAAR | DYETAKNYFK | 
    1226:
    KGLKDMGYGN | WISKPQEEKN | FYLCPV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    MIM:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human DRADA
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    ELISA Kit for Human DRADA
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    CLIA Kit for Human DRADA
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    CLIA Kit for Human DRADA
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    CLIA Kit for Human DRADA
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    U10803m
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    Packing:
    96T
    Polyclonal Antibody for Human DRADA
    Cat.:
    P10803Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human DRADA
    Polyclonal Antibody for Human DRADA
    Monoclonal Antibody for Human DRADA
    Monoclonal Antibody for Human DRADA
    Monoclonal Antibody for Human DRADA
    Protein for Human DRADA
    Protein for Human DRADA
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    R10803h
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Human DRADA

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing."
      Kim U. , Wang Y. , Sanford T. , Zeng Y. , Nishikura K.
      Proc. Natl. Acad. Sci. U.S.A.91:11457-11461(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;VARIANT GLY-100
    2. 2.
      "Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase."
      Patterson J.B. , Samuel C.E.
      Mol. Cell. Biol.15:5376-5388(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS GLY-100 AND ARG-384
      tissue: Kidney.
    3. 3.
      "Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase."
      Liu Y. , George C.X. , Patterson J.B. , Samuel C.E.
      J. Biol. Chem.272:4419-4428(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1; 2 AND 3);VARIANTS GLY-100 AND ARG-384
      tissue: Placenta.
    4. 4.
      "The gene coding for the interferon-inducible human dsRNA adenosine deaminase is transcribed into several messengers specifying different proteins."
      Deblandre G. , Marinx O. , Nols C. , Defrance P. , Berr P. , Huez G. , Caput D.
      Submitted (1996-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 5);VARIANTS GLY-100 AND ARG-384
      tissue: Cervix carcinoma.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4);VARIANTS GLY-100 AND ARG-384
      tissue: Amygdala.
      tissue: Fetal kidney.
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLY-100
      tissue: Lymph.
    9. 9.
      "Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible."
      George C.X. , Samuel C.E.
      Proc. Natl. Acad. Sci. U.S.A.96:4621-4626(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE PROMOTER USAGE;INDUCTION
    10. 10.
      "Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA."
      Cho D.-S.C. , Yang W. , Lee J.T. , Shiekhattar R. , Murray J.M. , Nishikura K.
      J. Biol. Chem.278:17093-17102(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HOMODIMERIZATION
    11. 11.
      "Dynamic association of RNA-editing enzymes with the nucleolus."
      Desterro J.M.P. , Keegan L.P. , Lafarga M. , Berciano M.T. , O'Connell M. , Carmo-Fonseca M.
      J. Cell Sci.116:1805-1818(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    12. 12.
      "ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells."
      Yang W. , Wang Q. , Howell K.L. , Lee J.T. , Cho D.-S.C. , Murray J.M. , Nishikura K.
      J. Biol. Chem.280:3946-3953(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    13. 13.
      "New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1."
      Taylor D.R. , Puig M. , Darnell M.E. , Mihalik K. , Feinstone S.M.
      J. Virol.79:6291-6298(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-418;MUTAGENESIS OF LYS-418
    15. 15.
      "ADAR1 interacts with NF90 through double-stranded RNA and regulates NF90-mediated gene expression independently of RNA editing."
      Nie Y. , Ding L. , Kao P.N. , Braun R. , Yang J.-H.
      Mol. Cell. Biol.25:6956-6963(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ILF2 AND ILF3
    16. 16.
      "The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells."
      Hartwig D. , Schuette C. , Warnecke J. , Dorn I. , Hennig H. , Kirchner H. , Schlenke P.
      J. Viral Hepat.13:150-157(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    17. 17.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-808;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    18. 18.
      "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."
      Yu L.R. , Zhu Z. , Chan K.C. , Issaq H.J. , Dimitrov D.S. , Veenstra T.D.
      J. Proteome Res.6:4150-4162(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-808;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    19. 19.
      "Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection."
      Nie Y. , Hammond G.L. , Yang J.H.
      J. Virol.81:917-923(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH EIF2AK2
    20. 20.
      "Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation."
      Cenci C. , Barzotti R. , Galeano F. , Corbelli S. , Rota R. , Massimi L. , Di Rocco C. , O'Connell M.A. , Gallo A.
      J. Biol. Chem.283:7251-7260(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;SUBUNIT;TISSUE SPECIFICITY
    21. 21.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-808;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    22. 22.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-601; SER-614; SER-823 AND SER-825;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    23. 23.
      "The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus."
      Agranat L. , Raitskin O. , Sperling J. , Sperling R.
      Proc. Natl. Acad. Sci. U.S.A.105:5028-5033(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UPF1;SUBCELLULAR LOCATION
    24. 24.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    25. 25.
      "RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR."
      Toth A.M. , Li Z. , Cattaneo R. , Samuel C.E.
      J. Biol. Chem.284:29350-29356(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    26. 26.
      "ADAR1 interacts with PKR during human immunodeficiency virus infection of lymphocytes and contributes to viral replication."
      Clerzius G. , Gelinas J.F. , Daher A. , Bonnet M. , Meurs E.F. , Gatignol A.
      J. Virol.83:10119-10128(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH EIF2AK2
    27. 27.
      "RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1."
      Fritz J. , Strehblow A. , Taschner A. , Schopoff S. , Pasierbek P. , Jantsch M.F.
      Mol. Cell. Biol.29:1487-1497(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH TNFO1 AND XPO1
    28. 28.
      "Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection."
      Doria M. , Neri F. , Gallo A. , Farace M.G. , Michienzi A.
      Nucleic Acids Res.37:5848-5858(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    29. 29.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-601 AND THR-808;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    30. 30.
      "Functions and regulation of RNA editing by ADAR deaminases."
      Nishikura K.
      Annu. Rev. Biochem.79:321-349(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    31. 31.
      "Human BLCAP transcript: new editing events in normal and cancerous tissues."
      Galeano F. , Leroy A. , Rossetti C. , Gromova I. , Gautier P. , Keegan L.P. , Massimi L. , Di Rocco C. , O'Connell M.A. , Gallo A.
      Int. J. Cancer127:127-137(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    32. 32.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-808 AND SER-825;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    33. 33.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    34. 34.
      "RNA editing catalyzed by ADAR1 and its function in mammalian cells."
      Wang Q.
      Biochemistry (Mosc.)76:900-911(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    35. 35.
      "ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor."
      Doria M. , Tomaselli S. , Neri F. , Ciafre S.A. , Farace M.G. , Michienzi A. , Gallo A.
      J. Gen. Virol.92:1228-1232(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    36. 36.
      "Adenosine deaminases acting on RNA, RNA editing, and interferon action."
      George C.X. , Gan Z. , Liu Y. , Samuel C.E.
      J. Interferon Cytokine Res.31:99-117(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    37. 37.
      "Enhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinase."
      Gelinas J.F. , Clerzius G. , Shaw E. , Gatignol A.
      J. Virol.85:8460-8466(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    38. 38.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-825;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    39. 39.
      "Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral."
      Samuel C.E.
      Virology411:180-193(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    40. 40.
      "A-to-I editing of protein coding and noncoding RNAs."
      Mallela A. , Nishikura K.
      Crit. Rev. Biochem. Mol. Biol.47:493-501(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    41. 41.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    42. 42.
      "Adenosine deaminase acting on RNA 1 (ADAR1) suppresses the induction of interferon by measles virus."
      Li Z. , Okonski K.M. , Samuel C.E.
      J. Virol.86:3787-3794(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    43. 43.
      "Activity regulation of adenosine deaminases acting on RNA (ADARs)."
      Orlandi C. , Barbon A. , Barlati S.
      Mol. Neurobiol.45:61-75(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    44. 44.
      "Crystal structure of the Z alpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA."
      Schwartz T. , Rould M.A. , Lowenhaupt K. , Herbert A. , Rich A.
      Science284:1841-1845(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 133-209 IN COMPLEX WITH Z-DNA
    45. 45.
      "The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA."
      Schade M. , Turner C.J. , Kuehne R. , Schmieder P. , Lowenhaupt K. , Herbert A. , Rich A. , Oschkinat H.
      Proc. Natl. Acad. Sci. U.S.A.96:12465-12470(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 125-201 IN COMPLEX WITH Z-DNA AND ALONE
    46. 46.
      "Mutations of the RNA-specific adenosine deaminase gene (DSRAD) are involved in dyschromatosis symmetrica hereditaria."
      Miyamura Y. , Suzuki T. , Kono M. , Inagaki K. , Ito S. , Suzuki N. , Tomita Y.
      Am. J. Hum. Genet.73:693-699(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS DSH PRO-923 AND SER-1165
    47. 47.
      "Seven novel mutations of the ADAR gene in Chinese families and sporadic patients with dyschromatosis symmetrica hereditaria (DSH)."
      Zhang X.-J. , He P.-P. , Li M. , He C.-D. , Yan K.-L. , Cui Y. , Yang S. , Zhang K.-Y. , Gao M. , Chen J.-J. , Li C.-R. , Jin L. , Chen H.-D. , Xu S.-J. , Huang W.
      Hum. Mutat.23:629-630(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DSH PHE-966
    48. 48.
      "A new arginine substitution mutation of DSRAD gene in a Chinese family with dyschromatosis symmetrica hereditaria."
      Li C.-R. , Li M. , Ma H.-J. , Luo D. , Yang L.-J. , Wang D.-G. , Zhu X.-H. , Yue X.-Z. , Chen W.-Q. , Zhu W.-Y.
      J. Dermatol. Sci.37:95-99(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DSH TRP-1155
    49. 49.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-806
    50. 50.
      "Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature."
      Rice G.I. , Kasher P.R. , Forte G.M. , Mannion N.M. , Greenwood S.M. , Szynkiewicz M. , Dickerson J.E. , Bhaskar S.S. , Zampini M. , Briggs T.A. , Jenkinson E.M. , Bacino C.A. , Battini R. , Bertini E. , Brogan P.A. , Brueton L.A. , Carpanelli M. , De Laet C. , more...
      Nat. Genet.44:1243-1248(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AGS6 ALA-193; THR-870; THR-872; HIS-892; ASN-999; ARG-1007; PHE-1112 AND HIS-1113
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