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Index > Protein center > DNM1(Gene name) > Human
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  • DNM1 (Gene name),
  • Dynamin-1 (Protein name ),  DYN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    DNM1(DNM);
    Protein name:
    Dynamin-1;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CAV1 and SH3GLB1. Binds SH3GL1, SH3GL2 and SH3GL3 (By similarity). Interacts with PHOCN (By similarity). Interacts with SNX9.
    Function:
    Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
    Subcellular Location:
    Cytoplasm Cytoplasm cytoskeleton Microtubule-associated.
    Protein Attributes:
    Sequence length:
    864
    Sequence:
    50:
    MGNRGMEDLI | PLVNRLQDAF | SAIGQNADLD | LPQIAVVGGQ | SAGKSSVLEN | 
    100:
    FVGRDFLPRG | SGIVTRRPLV | LQLVNATTEY | AEFLHCKGKK | FTDFEEVRLE | 
    150:
    IEAETDRVTG | TNKGISPVPI | NLRVYSPHVL | NLTLVDLPGM | TKVPVGDQPP | 
    200:
    DIEFQIRDML | MQFVTKENCL | ILAVSPANSD | LANSDALKVA | KEVDPQGQRT | 
    250:
    IGVITKLDLM | DEGTDARDVL | ENKLLPLRRG | YIGVVNRSQK | DIDGKKDITA | 
    300:
    ALAAERKFFL | SHPSYRHLAD | RMGTPYLQKV | LNQQLTNHIR | DTLPGLRNKL | 
    350:
    QSQLLSIEKE | VEEYKNFRPD | DPARKTKALL | QMVQQFAVDF | EKRIEGSGDQ | 
    400:
    IDTYELSGGA | RINRIFHERF | PFELVKMEFD | EKELRREISY | AIKNIHGIRT | 
    450:
    GLFTPDMAFE | TIVKKQVKKI | REPCLKCVDM | VISELISTVR | QCTKKLQQYP | 
    500:
    RLREEMERIV | TTHIREREGR | TKEQVMLLID | IELAYMNTNH | EDFIGFANAQ | 
    550:
    QRSNQMNKKK | TSGNQDEILV | IRKGWLTINN | IGIMKGGSKE | YWFVLTAENL | 
    600:
    SWYKDDEEKE | KKYMLSVDNL | KLRDVEKGFM | SSKHIFALFN | TEQRNVYKDY | 
    650:
    RQLELACETQ | EEVDSWKASF | LRAGVYPERV | GDKEKASETE | ENGSDSFMHS | 
    700:
    MDPQLERQVE | TIRNLVDSYM | AIVNKTVRDL | MPKTIMHLMI | NNTKEFIFSE | 
    750:
    LLANLYSCGD | QNTLMEESAE | QAQRRDEMLR | MYHALKEALS | IIGDINTTTV | 
    800:
    STPMPPPVDD | SWLQVQSVPA | GRRSPTSSPT | PQRRAPAVPP | ARPGSRGPAP | 
    850:
    GPPPAGSALG | GAPPVPSRPG | ASPDPFGPPP | QVPSRPNRAP | PGVPSRSGQA | 
    864:
    SPSRPESPRP | PFDL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    SMR:
    UniGene:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Dynamin-1
    Cat.:
    E1962h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Dynamin-1
    Cat.:
    E1962b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Dynamin-1
    Cat.:
    E1962r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Dynamin-1
    Cat.:
    E1962m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Dynamin-1
    Cat.:
    U1962b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Dynamin-1
    Cat.:
    U1962h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Dynamin-1
    Cat.:
    U1962m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Dynamin-1
    Cat.:
    U1962r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Dynamin-1
    Cat.:
    P1962Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Dynamin-1
    Cat.:
    P1962Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Dynamin-1
    Cat.:
    P1962Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Dynamin-1
    Monoclonal Antibody for Human Dynamin-1
    Monoclonal Antibody for Human Dynamin-1
    Monoclonal Antibody for Human Dynamin-1
    Monoclonal Antibody for Human Dynamin-1
    Protein for Human Dynamin-1
    Protein for Human Dynamin-1
    Protein for Human Dynamin-1
    Protein for Human Dynamin-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mutations in human dynamin block an intermediate stage in coated vesicle formation."
      van der Bliek A.M. , Redelmeier T.E. , Tisdale E.J. , Meyerowitz E.M. , Schmid S.L.
      J. Cell Biol.122:553-563(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [MRNA] OF 387-466 (ISOFORM 2);NUCLEOTIDE SEQUENCE [MRNA] OF 726-856 (ISOFORMS 3 AND 4);MUTAGENESIS OF LYS-44;VARIANT ASN-744
    2. 2.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
      tissue: PNS.
    4. 4.
      "SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis."
      Soulet F. , Yarar D. , Leonard M. , Schmid S.L.
      Mol. Biol. Cell16:2058-2067(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH SNX9
    5. 5.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 6.
      "Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis."
      Krendel M. , Osterweil E.K. , Mooseker M.S.
      FEBS Lett.581:644-650(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MYO1E
    7. 7.
      "A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein."
      Schobel S. , Neumann S. , Hertweck M. , Dislich B. , Kuhn P.H. , Kremmer E. , Seed B. , Baumeister R. , Haass C. , Lichtenthaler S.F.
      J. Biol. Chem.283:14257-14268(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SNX33
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Platelet.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Three-dimensional solution structure of the pleckstrin homology domain from dynamin."
      Downing A.K. , Driscoll P.C. , Gout I. , Salim K. , Zvelebil M.J. , Waterfield M.D.
      Curr. Biol.4:884-891(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 511-630
    11. 11.
      "Crystal structure at 2.2-A resolution of the pleckstrin homology domain from human dynamin."
      Ferguson K.M. , Lemmon M.A. , Schlessinger J. , Sigler P.B.
      Cell79:199-209(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 509-633
    12. 12.
      "Crystal structure of the pleckstrin homology domain from dynamin."
      Timm D. , Salim K. , Gout I. , Guruprasad L. , Waterfield M. , Blundell T.
      Nat. Struct. Biol.1:782-788(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 509-630
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