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Index > Protein center > EFHD2(Gene name) > Human
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  • EFHD2 (Gene name),
  • EF-hand domain-containing protein D2 (Protein name ),  EFHD2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    EFHD2(SWS1);
    Protein name:
    EF-hand domain-containing protein D2;
    Alternative:
    Swiprosin-1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CASP9; with inactive form.
    Function:
    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
    Subcellular Location:
    Membrane raft In immature B-cell line WEHI231.
    Protein Attributes:
    Sequence length:
    240
    Sequence:
    50:
    MATDELATKL | SRRLQMEGEG | GGETPEQPGL | NGAAAAAAGA | PDEAAEALGS | 
    100:
    ADCELSAKLL | RRADLNQGIG | EPQSPSRRVF | NPYTEFKEFS | RKQIKDMEKM | 
    150:
    FKQYDAGRDG | FIDLMELKLM | MEKLGAPQTH | LGLKNMIKEV | DEDFDSKLSF | 
    200:
    REFLLIFRKA | AAGELQEDSG | LCVLARLSEI | DVSSEGVKGA | KSFFEAKVQA | 
    240:
    INVSSRFEEE | IKAEQEERKK | QAEEMKQRKA | AFKELQSTFK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    E7511h
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    96T
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    ELISA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    E7511m
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    96T
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    ELISA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    E7511r
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    96T
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    ELISA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    E7511b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    U7511b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    U7511h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    U7511r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human EF-hand domain-containing protein D2
    Cat.:
    U7511m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human EF-hand domain-containing protein D2
    Cat.:
    P7511Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human EF-hand domain-containing protein D2
    Cat.:
    P7511Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human EF-hand domain-containing protein D2
    Polyclonal Antibody for Human EF-hand domain-containing protein D2
    Monoclonal Antibody for Human EF-hand domain-containing protein D2
    Monoclonal Antibody for Human EF-hand domain-containing protein D2
    Monoclonal Antibody for Human EF-hand domain-containing protein D2
    Monoclonal Antibody for Human EF-hand domain-containing protein D2
    Protein for Human EF-hand domain-containing protein D2
    Protein for Human EF-hand domain-containing protein D2
    Protein for Human EF-hand domain-containing protein D2
    Protein for Human EF-hand domain-containing protein D2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
      tissue: Muscle.
      tissue: Testis.
      tissue: Uterus.
    4. 4.
      Bienvenut W.V. , Calvo F.
      Submitted (2008-02) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-12; 62-78; 103-118; 124-134; 139-159; 177-188 AND 230-240;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Cervix carcinoma.
    5. 5.
      Lubec G. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 63-77; 79-87; 160-176 AND 207-218;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Fetal brain cortex.
    6. 6.
      "Identification of specific proteins in different lymphocyte populations by proteomic tools."
      Vuadens F. , Gasparini D. , Deon C. , Sanchez J.-C. , Hochstrasser D.F. , Schneider P. , Tissot J.-D.
      Proteomics2:105-111(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION;TISSUE SPECIFICITY
    7. 7.
      "Identification of swiprosin 1 in human lymphocytes."
      Vuadens F. , Rufer N. , Kress A. , Corthesy P. , Schneider P. , Tissot J.-D.
      Proteomics4:2216-2220(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;IDENTIFICATION BY MASS SPECTROMETRY
    8. 8.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74 AND SER-76;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells."
      Checinska A. , Giaccone G. , Rodriguez J.A. , Kruyt F.A.E. , Jimenez C.R.
      J. Proteomics72:575-585(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CASP9;IDENTIFICATION BY MASS SPECTROMETRY
    14. 14.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    15. 15.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-233;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11; SER-74 AND SER-76;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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