Eng ELISA Kit for Mouse(Mus musculus) | EIAab.comEng ELISA Kit for Mouse(Mus musculus) | EIAab.com

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Eng (Gene name),

Endoglin (Protein name ), EGLN_MOUSE from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Gene name:

Eng(Edg);

Protein name:

Endoglin;

Alternative:

Cell surface MJ7/18 antigen;

CD:

CD105;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer that forms an heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It is able to bind TGF-beta 1, and 3 efficiently and TGF-beta 2 less efficiently. Interacts with TCTEX1D4. Interacts with ARRB2.

Function:

Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

653

Sequence:

50:

MDRGVLPLPI | TLLFVIYSFV | PTTGLAERVG | CDLQPVDPTR | GEVTFTTSQV |

100:

SEGCVAQAAN | AVREVHVLFL | DFPGMLSHLE | LTLQASKQNG | TETQEVFLVL |

150:

VSNKNVFVKF | QAPEIPLHLA | YDSSLVIFQG | QPRVNITVLP | SLTSRKQILD |

200:

WAATKGAITS | IAALDDPQSI | VLQLGQDPKA | PFLCLPEAHK | DMGATLEWQP |

250:

RAQTPVQSCR | LEGVSGHKEA | YILRILPGSE | AGPRTVTVMM | ELSCTSGDAI |

300:

LILHGPPYVS | WFIDINHSMQ | ILTTGEYSVK | IFPGSKVKGV | ELPDTPQGLI |

350:

AEARKLNASI | VTSFVELPLV | SNVSLRASSC | GGVFQTTPAP | VVTTPPKDTC |

400:

SPVLLMSLIQ | PKCGNQVMTL | ALNKKHVQTL | QCTITGLTFW | DSSCQAEDTD |

450:

DHLVLSSAYS | SCGMKVTAHV | VSNEVIISFP | SGSPPLRKKV | QCIDMDSLSF |

500:

QLGLYLSPHF | LQASNTIELG | QQAFVQVSVS | PLTSEVTVQL | DSCHLDLGPE |

550:

GDMVELIQSR | TAKGSCVTLL | SPSPEGDPRF | SFLLRVYMVP | TPTAGTLSCN |

600:

LALRPSTLSQ | EVYKTVSMRL | NIVSPDLSGK | GLVLPSVLGI | TFGAFLIGAL |

650:

LTAALWYIYS | HTRGPSKREP | VVAVAAPASS | ESSSTNHSIG | STQSTPCSTS |

653:

SMA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Pfam:

KEGG:

UniGene:

String:

Uniprot:

FOR

ELISA Kit for Mouse Endoglin

Cat.:

E0980m

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse Endoglin

Cat.:

E0980h

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse Endoglin

Cat.:

E0980p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Endoglin

Cat.:

U0980h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse Endoglin

Cat.:

U0980p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Endoglin

Cat.:

U0980m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Endoglin

Polyclonal Antibody for Mouse Endoglin

Cat.:

P0980Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Endoglin

Cat.:

P0980Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Endoglin

Monoclonal Antibody for Mouse Endoglin

Monoclonal Antibody for Mouse Endoglin

Protein for Mouse Endoglin

Protein for Mouse Endoglin

Protein for Mouse Endoglin

R&D Technical Data

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Western blot - Anti-NAMPT antibody

12% SDS-PAGE analysis

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Precision

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Recovery

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Linearity

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References

1.

"Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF-beta ligand."
Ge A.Z. , Butcher E.C.
Gene138:201-206(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells."
St Jacques S. , Cymerman U. , Pece N. , Letarte M.
Endocrinology134:2645-2657(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: CD-1.
tissue: Placenta.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Salivary gland.
6.

"ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration."
Ray B.N. , Lee N.Y. , How T. , Blobe G.C.
Carcinogenesis31:435-441(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-641 AND SER-644
7.

"Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies."
Nolan-Stevaux O. , Zhong W. , Culp S. , Shaffer K. , Hoover J. , Wickramasinghe D. , Ruefli-Brasse A.
PLoS ONE7:E50920-E50920(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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