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Index > Protein center > Alcam(Gene name) > Mouse
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  • Alcam (Gene name),
  • CD166 antigen (Protein name ),  CD166_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Alcam;
    Protein name:
    CD166 antigen;
    Alternative:
    Protein DM-GRASP;Activated leukocyte cell adhesion molecule;
    CD:
    CD166;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    583
    Sequence:
    50:
    MASKVSPSCR | LVFCLLISAA | VLRPGLGWYT | VNSAYGDTIV | MPCRLDVPQN | 
    100:
    LMFGKWKYEK | PDGSPVFIAF | RSSTKKSVQY | DDVPEYKDRL | SLSENYTLSI | 
    150:
    ANAKISDEKR | FVCMLVTEDN | VFEAPTLVKV | FKQPSKPEIV | NKAPFLETDQ | 
    200:
    LKKLGDCISR | DSYPDGNITW | YRNGKVLQPV | EGEVAILFKK | EIDPGTQLYT | 
    250:
    VTSSLEYKTT | RSDIQMPFTC | SVTYYGPSGQ | KTIYSEQEIF | DIYYPTEQVT | 
    300:
    IQVLPPKNAI | KEGDNITLQC | LGNGNPPPEE | FMFYLPGQPE | GIRSSNTYTL | 
    350:
    TDVRRNATGD | YKCSLIDKRN | MAASTTITVH | YLDLSLNPSG | EVTKQIGDTL | 
    400:
    PVSCTISASR | NATVVWMKDN | IRLRSSPSFS | SLHYQDAGNY | VCETALQEVE | 
    450:
    GLKKRESLTL | IVEGKPQIKM | TKKTDPSGLS | KTIICHVEGF | PKPAIHWTIT | 
    500:
    GSGSVINQTE | ESPYINGRYY | SKIIISPEEN | VTLTCTAENQ | LERTVNSLNV | 
    550:
    SAISIPEHDE | ADDISDENRE | KVNDQAKLIV | GIVVGLLLAA | LVAGVVYWLY | 
    583:
    MKKSKTASKH | VNKDLGNMEE | NKKLEENNHK | TEA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CD166 antigen
    Cat.:
    E0002h
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    Packing:
    96T
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    ELISA Kit for Mouse CD166 antigen
    Cat.:
    E0002m
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    MSDS:
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    96T
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    ELISA Kit for Mouse CD166 antigen
    Cat.:
    E0002b
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    96T
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    ELISA Kit for Mouse CD166 antigen
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    E0002c
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    ELISA Kit for Mouse CD166 antigen
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    E0002d
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    ELISA Kit for Mouse CD166 antigen
    Cat.:
    E0002r
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    96T
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    ELISA Kit for Mouse CD166 antigen
    MSDS:
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    CLIA Kit for Mouse CD166 antigen
    Cat.:
    U0002d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse CD166 antigen
    Cat.:
    U0002c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CD166 antigen
    Cat.:
    U0002r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse CD166 antigen
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse CD166 antigen
    Cat.:
    U0002b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CD166 antigen
    Cat.:
    U0002m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse CD166 antigen
    Cat.:
    U0002h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Mouse CD166 antigen
    Cat.:
    P0002Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CD166 antigen
    Cat.:
    P0002Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CD166 antigen
    Polyclonal Antibody for Mouse CD166 antigen
    Polyclonal Antibody for Mouse CD166 antigen
    Polyclonal Antibody for Mouse CD166 antigen
    Cat.:
    P0002Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CD166 antigen
    Monoclonal Antibody for Mouse CD166 antigen
    Monoclonal Antibody for Mouse CD166 antigen
    Monoclonal Antibody for Mouse CD166 antigen
    Monoclonal Antibody for Mouse CD166 antigen
    Monoclonal Antibody for Mouse CD166 antigen
    Monoclonal Antibody for Mouse CD166 antigen
    Monoclonal Antibody for Mouse CD166 antigen
    Protein for Mouse CD166 antigen
    Protein for Mouse CD166 antigen
    Protein for Mouse CD166 antigen
    Protein for Mouse CD166 antigen
    Protein for Mouse CD166 antigen
    Protein for Mouse CD166 antigen
    Protein for Mouse CD166 antigen

    R&D Technical Data
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    s

    测试

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.3%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤6.9%

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    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    93-105

    Plasma

    101

    95-106

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    95-104%

    97-106%

    95-103%

    94-107%

    EDTA plasma(n=5)

    91-97%

    90-100%

    93-99%

    92-103%

    heparin plasma(n=5)

    94-103%

     

    96-108%

    97-109%

    93-106%

     

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    References
    1. 1.
      "Characterization of mouse ALCAM (CD166): the CD6 binding domain is conserved in different homologs and mediates cross-species binding."
      Bowen M.A. , Bajorath J. , D'Egidio M. , Whitney G.S. , Palmer D. , Kobarg J. , Starling G.C. , Siadak A.W. , Aruffo A.
      Eur. J. Immunol.27:1469-1478(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: NFS.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Thymus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "The molecular cloning and characterization of potential chick DM-GRASP homologs in zebrafish and mouse."
      Kanki J.P. , Chang S. , Kuwada J.Y.
      J. Neurobiol.25:831-845(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 227-583
      strain: BALB/c.
      tissue: Brain.
    5. 5.
      "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
      Gundry R.L. , Raginski K. , Tarasova Y. , Tchernyshyov I. , Bausch-Fluck D. , Elliott S.T. , Boheler K.R. , Van Eyk J.E. , Wollscheid B.
      Mol. Cell. Proteomics8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-95; ASN-167; ASN-457; ASN-466; ASN-496; ASN-499 AND ASN-518
      tissue: Myoblast.
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