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Index > Protein center > CEACAM5(Gene name) > Human
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  • CEACAM5 (Gene name),
  • Carcinoembryonic antigen-related cell adhesion molecule 5 (Protein name ),  CEAM5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    CEACAM5(CEA);
    Protein name:
    Carcinoembryonic antigen-related cell adhesion molecule 5;
    Alternative:
    Meconium antigen 100;Carcinoembryonic antigen(CEA);
    CD:
    CD66e;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
    Function:
    Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    702
    Sequence:
    50:
    MESPSAPPHR | WCIPWQRLLL | TASLLTFWNP | PTTAKLTIES | TPFNVAEGKE | 
    100:
    VLLLVHNLPQ | HLFGYSWYKG | ERVDGNRQII | GYVIGTQQAT | PGPAYSGREI | 
    150:
    IYPNASLLIQ | NIIQNDTGFY | TLHVIKSDLV | NEEATGQFRV | YPELPKPSIS | 
    200:
    SNNSKPVEDK | DAVAFTCEPE | TQDATYLWWV | NNQSLPVSPR | LQLSNGNRTL | 
    250:
    TLFNVTRNDT | ASYKCETQNP | VSARRSDSVI | LNVLYGPDAP | TISPLNTSYR | 
    300:
    SGENLNLSCH | AASNPPAQYS | WFVNGTFQQS | TQELFIPNIT | VNNSGSYTCQ | 
    350:
    AHNSDTGLNR | TTVTTITVYA | EPPKPFITSN | NSNPVEDEDA | VALTCEPEIQ | 
    400:
    NTTYLWWVNN | QSLPVSPRLQ | LSNDNRTLTL | LSVTRNDVGP | YECGIQNKLS | 
    450:
    VDHSDPVILN | VLYGPDDPTI | SPSYTYYRPG | VNLSLSCHAA | SNPPAQYSWL | 
    500:
    IDGNIQQHTQ | ELFISNITEK | NSGLYTCQAN | NSASGHSRTT | VKTITVSAEL | 
    550:
    PKPSISSNNS | KPVEDKDAVA | FTCEPEAQNT | TYLWWVNGQS | LPVSPRLQLS | 
    600:
    NGNRTLTLFN | VTRNDARAYV | CGIQNSVSAN | RSDPVTLDVL | YGPDTPIISP | 
    650:
    PDSSYLSGAN | LNLSCHSASN | PSPQYSWRIN | GIPQQHTQVL | FIAKITPNNN | 
    700:
    GTYACFVSNL | ATGRNNSIVK | SITVSASGTS | PGLSAGATVG | IMIGVLVGVA | 
    702:
    LI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    MIM:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Cat.:
    E0150m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Cat.:
    E0150h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Cat.:
    U0150h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Cat.:
    U0150m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Cat.:
    P0150Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Cat.:
    P0150Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Monoclonal Antibody for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Protein for Human Carcinoembryonic antigen-related cell adhesion molecule 5
    Protein for Human Carcinoembryonic antigen-related cell adhesion molecule 5

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen."
      Beauchemin N. , Benchimol S. , Cournoyer D. , Fuks A. , Stanners C.P.
      Mol. Cell. Biol.7:3221-3230(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLU-398
    2. 2.
      "Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains."
      Barnett T. , Goebel S.J. , Nothdurft M.A. , Elting J.J.
      Genomics3:59-66(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLU-398
    3. 3.
      "Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression."
      Schrewe H. , Thompson J. , Bona M. , Hefta L.J.F. , Maruya A. , Hassauer M. , Shively J.E. , von Kleist S. , Zimmermann W.
      Mol. Cell. Biol.10:2738-2748(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLU-398
    4. 4.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence."
      Oikawa S. , Nakazato H. , Kosaki G.
      Biochem. Biophys. Res. Commun.142:511-518(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 5-702 (ISOFORM 2);VARIANT GLU-398
    6. 6.
      "Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure."
      Zimmermann W. , Ortlieb B. , Friedrich R. , von Kleist S.
      Proc. Natl. Acad. Sci. U.S.A.84:2960-2964(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 331-702 (ISOFORM 1);VARIANT GLU-398
    7. 7.
      "Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion."
      Taheri M. , Saragovi U. , Fuks A. , Makkerh J. , Mort J. , Stanners C.P.
      J. Biol. Chem.275:26935-26943(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF SER-66; TYR-68; LYS-69 AND GLN-78;SUBCELLULAR LOCATION
    8. 8.
      "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
      Ramachandran P. , Boontheung P. , Xie Y. , Sondej M. , Wong D.T. , Loo J.A.
      J. Proteome Res.5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-560
      tissue: Saliva.
    9. 9.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-246
      tissue: Liver.
    10. 10.
      "Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23."
      Boehm M.K. , Perkins S.J.
      FEBS Lett.475:11-16(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 35-676
    11. 11.
      "Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation."
      Korotkova N. , Yang Y. , Le Trong I. , Cota E. , Demeler B. , Marchant J. , Thomas W.E. , Stenkamp R.E. , Moseley S.L. , Matthews S.
      Mol. Microbiol.67:420-434(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 34-144 IN COMPLEX WITH E.COLI DR ADHESIN;SUBUNIT;SUBCELLULAR LOCATION;MUTAGENESIS OF PHE-63; SER-66; VAL-73; ASP-74; GLN-78; ILE-125; LEU-129 AND GLU-133
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