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Index > Protein center > PFKFB4(Gene name) > Human
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  • PFKFB4 (Gene name),
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (Protein name ),  F264_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PFKFB4;
    Protein name:
    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4(6PF-2-K/Fru-2,6-P2ase 4;PFK/FBPase 4);
    Alternative:
    6PF-2-K/Fru-2,6-P2ase testis-type isozyme;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Synthesis and degradation of fructose 2,6-bisphosphate.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    469
    Sequence:
    50:
    MASPRELTQN | PLKKIWMPYS | NGRPALHACQ | RGVCMTNCPT | LIVMVGLPAR | 
    100:
    GKTYISKKLT | RYLNWIGVPT | REFNVGQYRR | DVVKTYKSFE | FFLPDNEEGL | 
    150:
    KIRKQCALAA | LRDVRRFLSE | EGGHVAVFDA | TNTTRERRAT | IFNFGEQNGY | 
    200:
    KTFFVESICV | DPEVIAANIV | QVKLGSPDYV | NRDSDEATED | FMRRIECYEN | 
    250:
    SYESLDEDLD | RDLSYIKIMD | VGQSYVVNRV | ADHIQSRIVY | YLMNIHVTPR | 
    300:
    SIYLCRHGES | ELNLKGRIGG | DPGLSPRGRE | FAKSLAQFIS | DQNIKDLKVW | 
    350:
    TSQMKRTIQT | AEALGVPYEQ | WKVLNEIDAG | VCEEMTYEEI | QDNYPLEFAL | 
    400:
    RDQDKYRYRY | PKGESYEDLV | QRLEPVIMEL | ERQENVLVIC | HQAVMRCLLA | 
    450:
    YFLDKAAEQL | PYLKCPLHTV | LKLTPVAYGC | KVESIFLNVA | AVNTHRDRPQ | 
    469:
    NVDISRPPEE | ALVTVPAHQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    MIM:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    E10217h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    E10217m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    E10217r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    U10217m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    U10217r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    U10217h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    P10217Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    P10217Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    P10217Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human 6PF-2-K/Fru-2,6-P2ase 4
    Monoclonal Antibody for Human 6PF-2-K/Fru-2,6-P2ase 4
    Monoclonal Antibody for Human 6PF-2-K/Fru-2,6-P2ase 4
    Protein for Human 6PF-2-K/Fru-2,6-P2ase 4
    Protein for Human 6PF-2-K/Fru-2,6-P2ase 4
    Protein for Human 6PF-2-K/Fru-2,6-P2ase 4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation."
      Minchenko O. , Opentanova I. , Minchenko D. , Ogura T. , Esumi H.
      FEBS Lett.576:14-20(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);ALTERNATIVE SPLICING
    2. 2.
      Sakakibara R.
      Submitted (1997-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Alternative splicing of human 6-phosphofructo-2-kinase/fructose-2,6-phosphatase 4 in melanoma cells."
      Minchenko O.H. , Opentanova I.L. , Minchenko D.O. , Kurashima Y. , Esumi H.
      Submitted (2004-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);ALTERNATIVE SPLICING
    4. 4.
      "Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene."
      Manzano A. , Perez J.X. , Nadal M. , Estivill X. , Lange A. , Bartrons R.
      Gene229:83-89(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    5. 5.
      "Specific expression of pfkfb4 gene in spermatogonia germ cells and analysis of its 5'-flanking region."
      Gomez M. , Manzano A. , Navarro-Sabate A. , Duran J. , Obach M. , Perales J.C. , Bartrons R.
      FEBS Lett.579:357-362(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    9. 9.
      "Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta."
      Sakai A. , Kato M. , Fukasawa M. , Ishiguro M. , Furuya E. , Sakakibara R.
      J. Biochem.119:506-511(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 357-469 (ISOFORM 1)
      tissue: Placenta.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LYS-181
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