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Index > Protein center > Acpp(Gene name) > Mouse
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  • Acpp (Gene name),
  • Prostatic acid phosphatase (Protein name ),  PPAP_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Acpp;
    Protein name:
    Prostatic acid phosphatase;
    Alternative:
    Thiamine monophosphatase(TMPase);Fluoride-resistant acid phosphatase(FRAP);3.1.3.5;5'-nucleotidase(5'-NT);Ecto-5'-nucleotidase;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; dimer formation is required for phosphatase activity.
    Function:
    Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor.
    Subcellular Location:
    Isoform 2 Cell membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles. Colocalizes with LAMP2 on the lysosome membrane.
    Protein Attributes:
    Sequence length:
    381
    Sequence:
    50:
    MRAVPLPLSR | TASLSLGFLL | LLSLCLDPGQ | AKELKFVTLV | FRHGDRGPIE | 
    100:
    TFPTDPITES | SWPQGFGQLT | QWGMEQHYEL | GSYIRKRYGR | FLNDTYKHDQ | 
    150:
    IYIRSTDVDR | TLMSAMTNLA | ALFPPEGISI | WNPRLLWQPI | PVHTVSLSED | 
    200:
    RLLYLPFRDC | PRFEELKSET | LESEEFLKRL | HPYKSFLDTL | SSLSGFDDQD | 
    250:
    LFGIWSKVYD | PLFCESVHNF | TLPSWATEDA | MIKLKELSEL | SLLSLYGIHK | 
    300:
    QKEKSRLQGG | VLVNEILKNM | KLATQPQKYK | KLVMYSAHDT | TVSGLQMALD | 
    350:
    VYNGVLPPYA | SCHMMELYHD | KGGHFVEMYY | RNETQNEPYP | LTLPGCTHSC | 
    381:
    PLEKFAELLD | PVISQDWATE | CMATSSHQGR | N
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    E0168r
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    E0168h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    E0168m
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    Packing:
    96T
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    ELISA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    E0168b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    U0168b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    U0168r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    U0168m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Prostatic acid phosphatase
    Cat.:
    U0168h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Prostatic acid phosphatase
    Polyclonal Antibody for Mouse Prostatic acid phosphatase
    Cat.:
    P0168Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Prostatic acid phosphatase
    Cat.:
    P0168Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Prostatic acid phosphatase
    Cat.:
    P0168Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Prostatic acid phosphatase
    Monoclonal Antibody for Mouse Prostatic acid phosphatase
    Monoclonal Antibody for Mouse Prostatic acid phosphatase
    Monoclonal Antibody for Mouse Prostatic acid phosphatase
    Protein for Mouse Prostatic acid phosphatase
    Protein for Mouse Prostatic acid phosphatase
    Protein for Mouse Prostatic acid phosphatase
    Protein for Mouse Prostatic acid phosphatase

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    Linearity
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    References
    1. 1.
      "Sequence and expression of mouse prostatic acid phosphatase."
      Crew M.D. , Chatta G.S. , Borg C.D.
      Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      tissue: Head.
      tissue: Skin.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    6. 6.
      "Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine."
      Zylka M.J. , Sowa N.A. , Taylor-Blake B. , Twomey M.A. , Herrala A. , Voikar V. , Vihko P.
      Neuron60:111-122(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION AS AN ECTONUCLEOSIDASE;DISRUPTION PHENOTYPE;ENZYME ACTIVITY;TISSUE SPECIFICITY;FUNCTION
    7. 7.
      "Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats."
      Taylor-Blake B. , Zylka M.J.
      PLoS ONE5:E8674-E8674(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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