Protein name:
Lanosterol synthase ;
Alternative:
Oxidosqualene--lanosterol cyclase (OSC) ;2,3-epoxysqualene--lanosterol cyclase ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus.
Subcellular Location:
Endoplasmic reticulum membrane
Peripheral membrane protein
Protein Attributes:
50:
MTEGTCLRRR | GGPYKTEPAT | DLTRWRLHNE | LGRQRWTYYQ | AEEDPGREQT |
100:
GLEAHSLGLD | TTSYFKNLPK | AQTAHEGALN | GVTFYAKLQA | EDGHWAGDYG |
150:
GPLFLLPGLL | ITCHIAHIPL | PAGYREEMVR | YLRSVQLPDG | GWGLHIEDKS |
200:
TVFGTALSYV | SLRILGIGPD | DPDLVRARNI | LHKKGGAVAI | PSWGKFWLAV |
250:
LNVYSWEGIN | TLFPEMWLLP | EWFPAHPSTL | WCHCRQVYLP | MSYCYATRLS |
300:
ASEDPLVQSL | RQELYVEDYA | SIDWPAQKNN | VCPDDMYTPH | SWLLHVVYGL |
350:
LNLYERFHST | SLRKWAIQLL | YEHVAADDRF | TKCISIGPIS | KTVNMLIRWS |
400:
VDGPSSPAFQ | EHVSRIKDYL | WLGLDGMKMQ | GTNGSQTWDT | SFAVQALLEA |
450:
GAHRRPEFLP | CLQKAHEFLR | LSQVPDNNPD | YQKYYRHMHK | GGFPFSTLDC |
500:
GWIVADCTAE | ALKAVLLLQE | RCPSITEHVP | RERLYDAVAV | LLSMRNSDGG |
550:
FATYETKRGG | YLLELLNPSE | VFGDIMIDYT | YVECTSAVMQ | ALRHFREYFP |
600:
DHRATESRET | LNQGLDFCRK | KQRADGSWEG | SWGVCFTYGT | WFGLEAFACM |
650:
GHIYQNRTAC | AEVAQACHFL | LSRQMADGGW | GEDFESCEQR | RYVQSAGSQV |
700:
HSTCWALLGL | MAVRHPDISA | QERGIRCLLG | KQLPNGDWPQ | ENISGVFNKS |
733:
CAISYTNYRN | IFPIWALGRF | SSLYPDNTLA | GHI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Bovine
ELISA Kit for Rat Lanosterol synthase
ELISA Kit for Rat Lanosterol synthase
ELISA Kit for Rat Lanosterol synthase
ELISA Kit for Rat Lanosterol synthase
CLIA Kit for Rat Lanosterol synthase
CLIA Kit for Rat Lanosterol synthase
CLIA Kit for Rat Lanosterol synthase
CLIA Kit for Rat Lanosterol synthase
Polyclonal Antibody for Rat Lanosterol synthase
Polyclonal Antibody for Rat Lanosterol synthase
Polyclonal Antibody for Rat Lanosterol synthase
Polyclonal Antibody for Rat Lanosterol synthase
Monoclonal Antibody for Rat Lanosterol synthase
Monoclonal Antibody for Rat Lanosterol synthase
Monoclonal Antibody for Rat Lanosterol synthase
Monoclonal Antibody for Rat Lanosterol synthase
Protein for Rat Lanosterol synthase
Protein for Rat Lanosterol synthase
Protein for Rat Lanosterol synthase
Protein for Rat Lanosterol synthase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 129-154; 279-287 AND 439-470;FUNCTION;CATALYTIC ACTIVITY
strain :
Sprague-Dawley .
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Liver .
3.
"Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat."
Mori M.
,
Li G.
,
Abe I.
,
Nakayama J.
,
Guo Z.
,
Sawashita J.
,
Ugawa T.
,
Nishizono S.
,
Serikawa T.
,
Higuchi K.
,
Shumiya S.
J. Clin. Invest.116:395-404(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE