Protein name:
Cocaine esterase ;
Alternative:
3.1.1.56;Methylumbelliferyl-acetate deacetylase 2 ) ;3.1.1.1;Carboxylesterase 2 (CE-2;hCE-2) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine.
Subcellular Location:
Endoplasmic reticulum lumen
Protein Attributes:
50:
MRLHRLRARL | SAVACGLLLL | LVRGQGQDSA | SPIRTTHTGQ | VLGSLVHVKG |
100:
ANAGVQTFLG | IPFAKPPLGP | LRFAPPEPPE | SWSGVRDGTT | HPAMCLQDLT |
150:
AVESEFLSQF | NMTFPSDSMS | EDCLYLSIYT | PAHSHEGSNL | PVMVWIHGGA |
200:
LVFGMASLYD | GSMLAALENV | VVVIIQYRLG | VLGFFSTGDK | HATGNWGYLD |
250:
QVAALRWVQQ | NIAHFGGNPD | RVTIFGESAG | GTSVSSLVVS | PISQGLFHGA |
300:
IMESGVALLP | GLIASSADVI | STVVANLSAC | DQVDSEALVG | CLRGKSKEEI |
350:
LAINKPFKMI | PGVVDGVFLP | RHPQELLASA | DFQPVPSIVG | VNNNEFGWLI |
400:
PKVMRIYDTQ | KEMDREASQA | ALQKMLTLLM | LPPTFGDLLR | EEYIGDNGDP |
450:
QTLQAQFQEM | MADSMFVIPA | LQVAHFQCSR | APVYFYEFQH | QPSWLKNIRP |
500:
PHMKADHGDE | LPFVFRSFFG | GNYIKFTEEE | EQLSRKMMKY | WANFARNGNP |
550:
NGEGLPHWPL | FDQEEQYLQL | NLQPAVGRAL | KAHRLQFWKK | ALPQKIQELE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rabbit
ELISA Kit for Human Cocaine esterase
ELISA Kit for Human Cocaine esterase
CLIA Kit for Human Cocaine esterase
CLIA Kit for Human Cocaine esterase
Polyclonal Antibody for Human Cocaine esterase
Polyclonal Antibody for Human Cocaine esterase
Monoclonal Antibody for Human Cocaine esterase
Monoclonal Antibody for Human Cocaine esterase
Protein for Human Cocaine esterase
Protein for Human Cocaine esterase
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
tissue :
Small intestine .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 27-34; 57-70; 227-235; 300-305; 346-351; 447-454; 458-466; 535-540 AND 546-551;FUNCTION;CATALYTIC ACTIVITY;SUBUNIT;GLYCOSYLATION;BIOPHYSICOCHEMICAL PROPERTIES
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Liver .
4.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
5.
"The full-ORF clone resource of the German cDNA consortium."
Bechtel S.
,
Rosenfelder H.
,
Duda A.
,
Schmidt C.P.
,
Ernst U.
,
Wellenreuther R.
,
Mehrle A.
,
Schuster C.
,
Bahr A.
,
Bloecker H.
,
Heubner D.
,
Hoerlein A.
,
Michel G.
,
Wedler H.
,
Koehrer K.
,
Ottenwaelder B.
,
Poustka A.
,
Wiemann S.
,
Schupp I.
more...
BMC Genomics8:399-399(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Endometrial adenocarcinoma .
tissue :
Testis .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.
"The sequence and analysis of duplication-rich human chromosome 16."
Martin J.
,
Han C.
,
Gordon L.A.
,
Terry A.
,
Prabhakar S.
,
She X.
,
Xie G.
,
Hellsten U.
,
Chan Y.M.
,
Altherr M.
,
Couronne O.
,
Aerts A.
,
Bajorek E.
,
Black S.
,
Blumer H.
,
Branscomb E.
,
Brown N.C.
,
Bruno W.J.
,
Buckingham J.M.
,
Callen D.F.
,
Campbell C.S.
,
Campbell M.L.
,
Campbell E.W.
,
Caoile C.
,
Challacombe J.F.
,
Chasteen L.A.
,
Chertkov O.
,
Chi H.C.
,
Christensen M.
,
Clark L.M.
,
Cohn J.D.
,
Denys M.
,
Detter J.C.
,
Dickson M.
,
Dimitrijevic-Bussod M.
,
Escobar J.
,
Fawcett J.J.
,
Flowers D.
,
Fotopulos D.
,
Glavina T.
,
Gomez M.
,
Gonzales E.
,
Goodstein D.
,
Goodwin L.A.
,
Grady D.L.
,
Grigoriev I.
,
Groza M.
,
Hammon N.
,
Hawkins T.
,
Haydu L.
,
Hildebrand C.E.
,
Huang W.
,
Israni S.
,
Jett J.
,
Jewett P.B.
,
Kadner K.
,
Kimball H.
,
Kobayashi A.
,
Krawczyk M.-C.
,
Leyba T.
,
Longmire J.L.
,
Lopez F.
,
Lou Y.
,
Lowry S.
,
Ludeman T.
,
Manohar C.F.
,
Mark G.A.
,
McMurray K.L.
,
Meincke L.J.
,
Morgan J.
,
Moyzis R.K.
,
Mundt M.O.
,
Munk A.C.
,
Nandkeshwar R.D.
,
Pitluck S.
,
Pollard M.
,
Predki P.
,
Parson-Quintana B.
,
Ramirez L.
,
Rash S.
,
Retterer J.
,
Ricke D.O.
,
Robinson D.L.
,
Rodriguez A.
,
Salamov A.
,
Saunders E.H.
,
Scott D.
,
Shough T.
,
Stallings R.L.
,
Stalvey M.
,
Sutherland R.D.
,
Tapia R.
,
Tesmer J.G.
,
Thayer N.
,
Thompson L.S.
,
Tice H.
,
Torney D.C.
,
Tran-Gyamfi M.
,
Tsai M.
,
Ulanovsky L.E.
,
Ustaszewska A.
,
Vo N.
,
White P.S.
,
Williams A.L.
,
Wills P.L.
,
Wu J.-R.
,
Wu K.
,
Yang J.
,
DeJong P.
,
Bruce D.
,
Doggett N.A.
,
Deaven L.
,
Schmutz J.
,
Grimwood J.
,
Richardson P.
,
Rokhsar D.S.
,
Eichler E.E.
,
Gilna P.
,
Lucas S.M.
,
Myers R.M.
,
Rubin E.M.
,
Pennacchio L.A.
more...
Nature432:988-994(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Skin .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-111
tissue :
Liver .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HIS-206
12.
"Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2)."
Kim S.-R.
,
Nakamura T.
,
Saito Y.
,
Sai K.
,
Nakajima T.
,
Saito H.
,
Shirao K.
,
Minami H.
,
Ohtsu A.
,
Yoshida T.
,
Saijo N.
,
Ozawa S.
,
Sawada J.
Drug Metab. Pharmacokinet.18:327-332(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT TRP-34