FBN3 ELISA Kit for Human(Homo sapiens) | EIAab.comFBN3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > FBN3(Gene name) > Human

FBN3 (Gene name),

Fibrillin-3 (Protein name ), FBN3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FBN3(KIAA1776);

Protein name:

Fibrillin-3;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

2809

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2809:

RLKVQLQLL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00008

SMR:

Q75N90

MIM:

608529

UniGene:

Hs.370362

STRING:

9606.ENSP00000270509

Pfam:

PF12662

String:

Q75N90

KEGG:

hsa:84467

Uniprot:

Q75N90

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ELISA Kit for Human Fibrillin-3

Cat.:

E14934h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Fibrillin-3

Cat.:

U14934h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Human Fibrillin-3

Monoclonal Antibody for Human Fibrillin-3

Protein for Human Fibrillin-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤7.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤11.2%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of FBN3 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	97	95-103
Plasma	98	92-104

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of FBN3 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	94-105%	90-100%	95-105%	92-109%
EDTA plasma(n=5)	90-99%	92-105%	89-94%	93-106%
heparin plasma(n=5)	93-106%	94-110%	100-111%	95-110%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissues."
Corson G.M. , Charbonneau N.L. , Keene D.R. , Sakai L.Y.
Genomics83:461-472(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;VARIANTS ASN-662; SER-1614 AND ASP-2610
2.

"Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients."
Uyeda T. , Takahashi T. , Eto S. , Sato T. , Xu G. , Kanezaki R. , Toki T. , Yonesaka S. , Ito E.
J. Hum. Genet.49:404-407(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLN-473; ASN-662; LEU-935; PHE-938; TRP-1083; SER-1614; LYS-1869; PRO-1904 AND ASP-2610
3.

"Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T. , Nakayama M. , Nakajima D. , Kikuno R. , Ohara O.
DNA Res.8:85-95(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS ASN-662; ILE-1326; GLN-1806 AND ASP-2610
tissue: Brain.
4.

Nakajima D. , Nakayama M. , Kikuno R. , Nagase T. , Ohara O.
Submitted (2005-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
5.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

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