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Index > Protein center > FCER2(Gene name) > Human
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  • FCER2 (Gene name),
  • Low affinity immunoglobulin epsilon Fc receptor (Protein name ),  FCER2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FCER2(CD23A;CLEC4J;FCE2;IGEBF);
    Protein name:
    Low affinity immunoglobulin epsilon Fc receptor;
    Alternative:
    C-type lectin domain family 4 member J;BLAST-2;Immunoglobulin E-binding factor;Fc-epsilon-RII;Lymphocyte IgE receptor;
    CD:
    CD23;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein Secreted Also exists as a soluble excreted form.
    Protein Attributes:
    Sequence length:
    321
    Sequence:
    50:
    MEEGQYSEIE | ELPRRRCCRR | GTQIVLLGLV | TAALWAGLLT | LLLLWHWDTT | 
    100:
    QSLKQLEERA | ARNVSQVSKN | LESHHGDQMA | QKSQSTQISQ | ELEELRAEQQ | 
    150:
    RLKSQDLELS | WNLNGLQADL | SSFKSQELNE | RNEASDLLER | LREEVTKLRM | 
    200:
    ELQVSSGFVC | NTCPEKWINF | QRKCYYFGKG | TKQWVHARYA | CDDMEGQLVS | 
    250:
    IHSPEEQDFL | TKHASHTGSW | IGLRNLDLKG | EFIWVDGSHV | DYSNWAPGEP | 
    300:
    TSRSQGEDCV | MMRGSGRWND | AFCDRKLGAW | VCDRLATCTP | PASEGSAESM | 
    321:
    GPDSRPDPDG | RLPTPSAPLH | S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Low affinity immunoglobulin epsilon Fc receptor
    Cat.:
    E1007h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Low affinity immunoglobulin epsilon Fc receptor
    Cat.:
    E1007m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Low affinity immunoglobulin epsilon Fc receptor
    Cat.:
    U1007h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Low affinity immunoglobulin epsilon Fc receptor
    Cat.:
    U1007m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Low affinity immunoglobulin epsilon Fc receptor
    Cat.:
    P1007Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Low affinity immunoglobulin epsilon Fc receptor
    Cat.:
    P1007Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Low affinity immunoglobulin epsilon Fc receptor
    Monoclonal Antibody for Human Low affinity immunoglobulin epsilon Fc receptor
    Protein for Human Low affinity immunoglobulin epsilon Fc receptor
    Protein for Human Low affinity immunoglobulin epsilon Fc receptor

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins."
      Ikuta K. , Takami M. , Kim C.W. , Honjo T. , Miyoshi T. , Tagaya Y. , Kawabe T. , Yodoi J.
      Proc. Natl. Acad. Sci. U.S.A.84:819-823(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning and expression of the cDNA coding for a human lymphocyte IgE receptor."
      Luedin C. , Hofstetter H. , Sarfati M. , Levy C.A. , Suter U. , Alaimo D. , Kilchherr E. , Frost H. , Delespesse G.
      EMBO J.6:109-114(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: B-cell.
      tissue: Blood.
    6. 6.
      "Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression."
      Yokota A. , Kikutani H. , Tanaka T. , Sato R. , Barsumian E.L. , Suemura M. , Kishimoto T.
      Cell55:611-618(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "Partial characterization of natural and recombinant human soluble CD23."
      Rose K. , Turcatti G. , Graber P. , Pochon S. , Regamey P.-O. , Jansen K.U. , Magnenat E. , Aubonney N. , Bonnefoy J.-Y.
      Biochem. J.286:819-824(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;DISULFIDE BONDS
    8. 8.
      "The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10."
      Lemieux G.A. , Blumenkron F. , Yeung N. , Zhou P. , Williams J. , Grammer A.C. , Petrovich R. , Lipsky P.E. , Moss M.L. , Werb Z.
      J. Biol. Chem.282:14836-14844(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PROTEOLYTIC CLEAVAGE BY ADAM10
    9. 9.
      "Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23."
      Ivaldi C. , Martin B.R. , Kieffer-Jaquinod S. , Chapel A. , Levade T. , Garin J. , Journet A.
      PLoS ONE7:E37187-E37187(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-17 AND CYS-18;SUBCELLULAR LOCATION
      tissue: B-cell.
    10. 10.
      "Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23)."
      Padlan E.A. , Helm B.A.
      Receptor3:325-341(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF LECTIN DOMAIN
    11. 11.
      "Structure-based modeling of the ligand binding domain of the human cell surface receptor CD23 and comparison of two independently derived molecular models."
      Bajorath J. , Aruffo A.
      Protein Sci.5:240-247(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 173-285
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 156-298;DISULFIDE BONDS;SUBUNIT
    13. 13.
      "Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding."
      Wurzburg B.A. , Tarchevskaya S.S. , Jardetzky T.S.
      Structure14:1049-1058(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 150-321 ALONE AND IN COMPLEX WITH CALCIUM;DISULFIDE BONDS
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PHE-316
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