FCER1A ELISA Kit for Human(Homo sapiens) | EIAab.comFCER1A ELISA Kit for Human(Homo sapiens)

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FCER1A (Gene name),

High affinity immunoglobulin epsilon receptor subunit alpha (Protein name ), FCERA_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FCER1A(FCE1A);

Protein name:

High affinity immunoglobulin epsilon receptor subunit alpha;

Alternative:

IgE Fc receptor subunit alpha;Fc-epsilon RI-alpha(FcERI);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains.

Function:

Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.

Subcellular Location:

Cell membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

257

Sequence:

50:

100:

150:

200:

250:

257:

KPNPKNN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P12319

UniGene:

Hs.897

String:

P12319

Pfam:

PF00047

KEGG:

hsa:2205

STRING:

9606.ENSP00000315719

MIM:

147140

Uniprot:

P12319

FOR

ELISA Kit for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

E8982h

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Packing:

96T

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ELISA Kit for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

E8982m

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96T

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ELISA Kit for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

E8982r

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96T

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CLIA Kit for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

U8982h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

U8982m

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MSDS:

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Packing:

96T

CLIA Kit for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

U8982r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

P8982Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human High affinity immunoglobulin epsilon receptor subunit alpha

Cat.:

P8982Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human High affinity immunoglobulin epsilon receptor subunit alpha

Monoclonal Antibody for Human High affinity immunoglobulin epsilon receptor subunit alpha

Protein for Human High affinity immunoglobulin epsilon receptor subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor."
Kochan J. , Pettine L.F. , Hakimi J. , Kishi K. , Kinet J.-P.
Nucleic Acids Res.16:3584-3584(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products."
Shimizu A. , Tepler I. , Benfey P.N. , Berenstein E.H. , Siraganian R.P. , Leder P.
Proc. Natl. Acad. Sci. U.S.A.85:1907-1911(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
tissue: Mast cell.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Prostate.
4.

"High-level expression of the truncated alpha chain of human high-affinity receptor for IgE as a soluble form by baculovirus-infected insect cells. Biochemical characterization of the recombinant product."
Yagi S. , Yanagida M. , Tanida I. , Hasegawa A. , Okumura K. , Ra C.
Eur. J. Biochem.220:593-598(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 26-197
5.

"A modeling study of the alpha-subunit of human high-affinity receptor for immunoglobulin-E."
Padlan E.A. , Helm B.A.
Receptor2:129-144(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 26-197
6.

"Crystal structure of the human high-affinity IgE receptor."
Garman S.C. , Kinet J.P. , Jardetzky T.S.
Cell95:951-961(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 26-201;GLYCOSYLATION AT ASN-46; ASN-67 AND ASN-191;DISULFIDE BONDS
7.

"The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms."
Garman S.C. , Sechi S. , Kinet J.P. , Jardetzky T.S.
J. Mol. Biol.311:1049-1062(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 26-201;GLYCOSYLATION AT ASN-46; ASN-67; ASN-99; ASN-165 AND ASN-191;DISULFIDE BONDS

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