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Index > Protein center > FCGRT(Gene name) > Human
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  • FCGRT (Gene name),
  • IgG receptor FcRn large subunit p51 (Protein name ),  FCGRN_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FCGRT(FCRN);
    Protein name:
    IgG receptor FcRn large subunit p51(FcRn);
    Alternative:
    Neonatal Fc receptor;IgG Fc fragment receptor transporter alpha chain;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    FcRn complex consist of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer.
    Function:
    Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    365
    Sequence:
    50:
    MGVPRPQPWA | LGLLLFLLPG | SLGAESHLSL | LYHLTAVSSP | APGTPAFWVS | 
    100:
    GWLGPQQYLS | YNSLRGEAEP | CGAWVWENQV | SWYWEKETTD | LRIKEKLFLE | 
    150:
    AFKALGGKGP | YTLQGLLGCE | LGPDNTSVPT | AKFALNGEEF | MNFDLKQGTW | 
    200:
    GGDWPEALAI | SQRWQQQDKA | ANKELTFLLF | SCPHRLREHL | ERGRGNLEWK | 
    250:
    EPPSMRLKAR | PSSPGFSVLT | CSAFSFYPPE | LQLRFLRNGL | AAGTGQGDFG | 
    300:
    PNSDGSFHAS | SSLTVKSGDE | HHYCCIVQHA | GLAQPLRVEL | ESPAKSSVLV | 
    350:
    VGIVIGVLLL | TAAAVGGALL | WRRMRSGLPA | PWISLRGDDT | GVLLPTPGEA | 
    365:
    QDADLKDVNV | IPATA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    MIM:
    SMR:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human FcRn
    Cat.:
    E13790h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human FcRn
    Cat.:
    E13790r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human FcRn
    Cat.:
    E13790m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human FcRn
    Cat.:
    U13790h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Human FcRn
    MSDS:
    Please sign in first.
    CLIA Kit for Human FcRn
    Cat.:
    U13790m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human FcRn
    Polyclonal Antibody for Human FcRn
    Polyclonal Antibody for Human FcRn
    Monoclonal Antibody for Human FcRn
    Monoclonal Antibody for Human FcRn
    Monoclonal Antibody for Human FcRn
    Protein for Human FcRn
    Protein for Human FcRn
    Protein for Human FcRn

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus."
      Story C.M. , Mikulska J. , Simister N.E.
      J. Exp. Med.180:2377-2381(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    2. 2.
      "Partial sequence of the human fcgrt gene and its 5' upstream region."
      Tiwari B. , Junghans R.P.
      Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Cloning and analysis of the gene encoding the human neonatal Fc receptor."
      Mikulska J.E. , Pablo L. , Canel J. , Simister N.E.
      Eur. J. Immunogenet.27:231-240(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Rectum tumor.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    7. 7.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-38
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor."
      West A.P. Jr. , Bjorkman P.J.
      Biochemistry39:9698-9708(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 24-290
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