Protein name:
IgG receptor FcRn large subunit p51 (FcRn) ;
Alternative:
Neonatal Fc receptor ;IgG Fc fragment receptor transporter alpha chain ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
FcRn complex consist of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer.
Function:
Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MGVPRPQPWA | LGLLLFLLPG | SLGAESHLSL | LYHLTAVSSP | APGTPAFWVS |
100:
GWLGPQQYLS | YNSLRGEAEP | CGAWVWENQV | SWYWEKETTD | LRIKEKLFLE |
150:
AFKALGGKGP | YTLQGLLGCE | LGPDNTSVPT | AKFALNGEEF | MNFDLKQGTW |
200:
GGDWPEALAI | SQRWQQQDKA | ANKELTFLLF | SCPHRLREHL | ERGRGNLEWK |
250:
EPPSMRLKAR | PSSPGFSVLT | CSAFSFYPPE | LQLRFLRNGL | AAGTGQGDFG |
300:
PNSDGSFHAS | SSLTVKSGDE | HHYCCIVQHA | GLAQPLRVEL | ESPAKSSVLV |
350:
VGIVIGVLLL | TAAAVGGALL | WRRMRSGLPA | PWISLRGDDT | GVLLPTPGEA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Polyclonal Antibody for Human FcRn
Polyclonal Antibody for Human FcRn
Polyclonal Antibody for Human FcRn
Monoclonal Antibody for Human FcRn
Monoclonal Antibody for Human FcRn
Monoclonal Antibody for Human FcRn
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Placenta .
2.
"Partial sequence of the human fcgrt gene and its 5' upstream region."
Tiwari B.
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Junghans R.P.
Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
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BMC Genomics8:399-399(2007)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Rectum tumor .
5.
Mural R.J.
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Istrail S.
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Sutton G.G.
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Florea L.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 24-38
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 24-290