Protein name:
Fibroblast growth factor 10 (FGF-10) ;
Alternative:
Keratinocyte growth factor 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with FGFR1 and FGFR2. Interacts with FGFBP1.
Function:
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.
Subcellular Location:
Secreted
Protein Attributes:
50:
MWKWILTHCA | SAFPHLPGCC | CCCFLLLFLV | SSVPVTCQAL | GQDMVSPEAT |
100:
NSSSSSFSSP | SSAGRHVRSY | NHLQGDVRWR | KLFSFTKYFL | KIEKNGKVSG |
150:
TKKENCPYSI | LEITSVEIGV | VAVKAINSNY | YLAMNKKGKL | YGSKEFNNDC |
200:
KLKERIEENG | YNTYASFNWQ | HNGRQMYVAL | NGKGAPRRGQ | KTRRKNTSAH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Human FGF-10
ELISA Kit for Human FGF-10
ELISA Kit for Human FGF-10
CLIA Kit for Human FGF-10
CLIA Kit for Human FGF-10
CLIA Kit for Human FGF-10
Polyclonal Antibody for Human FGF-10
Polyclonal Antibody for Human FGF-10
Polyclonal Antibody for Human FGF-10
Monoclonal Antibody for Human FGF-10
Monoclonal Antibody for Human FGF-10
Monoclonal Antibody for Human FGF-10
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Structure and expression of human fibroblast growth factor-10."
Emoto H.
,
Tagashira S.
,
Mattei M.-G.
,
Yamasaki M.
,
Hashimoto G.
,
Katsumata T.
,
Negoro T.
,
Nakatsuka M.
,
Birnbaum D.
,
Coulier F.
,
Itoh N.
J. Biol. Chem.272:23191-23194(1997)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Lung .
2.
"Cutaneous wound healing by keratinocyte growth factor 2."
Jimenez P.A.
,
Gruber J.R.
,
Liu B.
,
Feng P.
,
Florence C.
,
Blunt A.
,
Huddleston K.A.
,
Teliska M.
,
Alfonso P.
,
Coleman T.A.
,
Ornitz D.M.
,
Dillon P.A.
,
Duan R.D.
Submitted (1997-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Lung .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
5.
"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Halleck A.
,
Ebert L.
,
Mkoundinya M.
,
Schick M.
,
Eisenstein S.
,
Neubert P.
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Kstrang K.
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Schatten R.
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Shen B.
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Henze S.
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Mar W.
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Korn B.
,
Zuo D.
,
Hu Y.
,
LaBaer J.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.
Mural R.J.
,
Istrail S.
,
Sutton G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
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Reinert K.
,
Remington K.A.
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Clark A.G.
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Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
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Myers E.W.
,
Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH FGFBP1
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH FGFR1 AND FGFR2;FUNCTION IN STIMULATION OF CELL PROLIFERATION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 69-208 IN COMPLEX WITH FGFR2
13.
"Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands."
Entesarian M.
,
Matsson H.
,
Klar J.
,
Bergendal B.
,
Olson L.
,
Arakaki R.
,
Hayashi Y.
,
Ohuchi H.
,
Falahat B.
,
Bolstad A.I.
,
Jonsson R.
,
Wahren-Herlenius M.
,
Dahl N.
Nat. Genet.37:125-127(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN ALSG
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT LADDS ARG-156
15.
"Mutations in different components of FGF signaling in LADD syndrome."
Rohmann E.
,
Brunner H.G.
,
Kayserili H.
,
Uyguner O.
,
Nuernberg G.
,
Lew E.D.
,
Dobbie A.
,
Eswarakumar V.P.
,
Uzumcu A.
,
Ulubil-Emeroglu M.
,
Leroy J.G.
,
Li Y.
,
Becker C.
,
Lehnerdt K.
,
Cremers C.W.R.J.
,
Yueksel-Apak M.
,
Nuernberg P.
,
Kubisch C.
,
Schlessinger J.
,
van Bokhoven H.
,
Wollnik B.
more...
Nat. Genet.38:414-417(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT LADDS PHE-106