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Index > Protein center > FGF5(Gene name) > Human
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  • FGF5 (Gene name),
  • Fibroblast growth factor 5 (Protein name ),  FGF5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    FGF5;
    Protein name:
    Fibroblast growth factor 5(FGF-5);
    Alternative:
    Smag-82;Heparin-binding growth factor 5(HBGF-5);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
    Function:
    Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    268
    Sequence:
    50:
    MSLSFLLLLF | FSHLILSAWA | HGEKRLAPKG | QPGPAATDRN | PRGSSSRQSS | 
    100:
    SSAMSSSSAS | SSPAASLGSQ | GSGLEQSSFQ | WSPSGRRTGS | LYCRVGIGFH | 
    150:
    LQIYPDGKVN | GSHEANMLSV | LEIFAVSQGI | VGIRGVFSNK | FLAMSKKGKL | 
    200:
    HASAKFTDDC | KFRERFQENS | YNTYASAIHR | TEKTGREWYV | ALNKRGKAKR | 
    250:
    GCSPRVKPQH | ISTHFLPRFK | QSEQPELSFT | VTVPEKKKPP | SPIKPKIPLS | 
    268:
    APRKNTNSVK | YRLKFRFG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human FGF-5
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    E0397h
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    ELISA Kit for Human FGF-5
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    E0397b
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    ELISA Kit for Human FGF-5
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    E0397m
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    ELISA Kit for Human FGF-5
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    E0397r
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    ELISA Kit for Human FGF-5
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    E0397d
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    96T
    CLIA Kit for Human FGF-5
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    U0397h
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    96T
    CLIA Kit for Human FGF-5
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    U0397b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human FGF-5
    Cat.:
    U0397r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human FGF-5
    Cat.:
    U0397d
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    96T
    CLIA Kit for Human FGF-5
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    U0397m
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    Packing:
    96T
    Polyclonal Antibody for Human FGF-5
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    P0397Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FGF-5
    Cat.:
    P0397Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FGF-5
    Cat.:
    P0397Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FGF-5
    Polyclonal Antibody for Human FGF-5
    Monoclonal Antibody for Human FGF-5
    Monoclonal Antibody for Human FGF-5
    Monoclonal Antibody for Human FGF-5
    Monoclonal Antibody for Human FGF-5
    Monoclonal Antibody for Human FGF-5
    Protein for Human FGF-5
    Protein for Human FGF-5
    Protein for Human FGF-5
    Protein for Human FGF-5
    Protein for Human FGF-5

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    References
    1. 1.
      "Expression of the murine fibroblast growth factor 5 gene in the adult central nervous system."
      Haub O. , Drucker B. , Goldfarb M.
      Proc. Natl. Acad. Sci. U.S.A.87:8022-8026(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
      tissue: Brain stem.
    2. 2.
      "The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors."
      Zhan X. , Bates B. , Hu X. , Goldfarb M.
      Mol. Cell. Biol.8:3487-3495(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "An alternatively-spliced FGF-5 mRNA is abundant in brain and translates into a partial agonist/antagonist for FGF-5 neurotrophic activity."
      Ozawa K. , Suzuki S. , Asada M. , Tomooka Y. , Li A. , Yoneda A. , Komi A. , Imamura T.
      Submitted (1998-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
    4. 4.
      "Differential display identification of 40 genes with altered expression in activated human smooth muscle cells. Local expression in atherosclerotic lesions of smags, smooth muscle activation-specific genes."
      de Vries C.J.M. , van Achterberg T.A.E. , Horrevoets A.J.G. , ten Cate J.W. , Pannekoek H.
      J. Biol. Chem.275:23939-23947(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
      tissue: Umbilical artery.
    5. 5.
      "Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas."
      Hanada K.-I. , Perry-Lalley D.M. , Ohnmacht G.A. , Bettinotti M.P. , Yang J.C.
      Cancer Res.61:5511-5516(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
    6. 6.
      NIEHS SNPs program
      Submitted (2005-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-54
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS SHORT AND LONG)
      tissue: Cerebellum.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG)
      tissue: Lung.
    10. 10.
      "Receptor specificity of the fibroblast growth factor family."
      Ornitz D.M. , Xu J. , Colvin J.S. , McEwen D.G. , MacArthur C.A. , Coulier F. , Gao G. , Goldfarb M.
      J. Biol. Chem.271:15292-15297(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFR1 AND FGFR2;FUNCTION IN CELL PROLIFERATION
    11. 11.
      "Fibroblast growth factor signalling: from development to cancer."
      Turner N. , Grose R.
      Nat. Rev. Cancer10:116-129(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
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