FGFBP1 ELISA Kit for Human(Homo sapiens) | EIAab.comFGFBP1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > FGFBP1(Gene name) > Human

FGFBP1 (Gene name),

Fibroblast growth factor-binding protein 1 (Protein name ), FGFP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FGFBP1(FGFBP;HBP17);

Protein name:

Fibroblast growth factor-binding protein 1(FGF-BP;FGF-BP1;FGF-binding protein 1;FGFBP-1);

Alternative:

17 kDa heparin-binding growth factor-binding protein(17 kDa HBGF-binding protein;HBp17);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGF1, FGF2, FGF7, FGF10, FGF22 and HSPG2.

Function:

Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.

Subcellular Location:

Secreted extracellular space Cell membrane Peripheral membrane protein Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.

Protein Attributes:

Sequence length:

234

Sequence:

50:

100:

150:

200:

234:

PDMANQRKTA | LEFCGETWSS | LCTFFLSIVQ | DTSC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:9982

String:

Q14512

MIM:

607737

UniGene:

Hs.1690

Pfam:

PF06473

STRING:

9606.ENSP00000259988

Uniprot:

Q14512

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ELISA Kit for Human FGF-BP

Cat.:

E1398h

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96T

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ELISA Kit for Human FGF-BP

Cat.:

E1398m

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96T

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ELISA Kit for Human FGF-BP

Cat.:

E1398b

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96T

ELISA Kit for Human FGF-BP

Cat.:

E1398r

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96T

CLIA Kit for Human FGF-BP

Cat.:

U1398b

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Packing:

96T

CLIA Kit for Human FGF-BP

Cat.:

U1398r

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96T

CLIA Kit for Human FGF-BP

Cat.:

U1398m

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96T

CLIA Kit for Human FGF-BP

Cat.:

U1398h

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96T

Polyclonal Antibody for Human FGF-BP

Cat.:

P1398Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human FGF-BP

Cat.:

P1398Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human FGF-BP

Cat.:

P1398Rb-r

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40ug/0.2ml

Monoclonal Antibody for Human FGF-BP

Protein for Human FGF-BP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Fibroblast growth factor-binding protein is a novel partner for perlecan protein core."
Mongiat M. , Otto J. , Oldershaw R. , Ferrer F. , Sato J.D. , Iozzo R.V.
J. Biol. Chem.276:10263-10271(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HSPG2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
2.

"Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein."
Tassi E. , Al-Attar A. , Aigner A. , Swift M.R. , McDonnell K. , Karavanov A. , Wellstein A.
J. Biol. Chem.276:40247-40253(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FGF2
3.

"The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair."
Beer H.-D. , Bittner M. , Niklaus G. , Munding C. , Max N. , Goppelt A. , Werner S.
Oncogene24:5269-5277(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FGF7; FGF10 AND FGF22;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.

"Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display."
Xie B. , Tassi E. , Swift M.R. , McDonnell K. , Bowden E.T. , Wang S. , Ueda Y. , Tomita Y. , Riegel A.T. , Wellstein A.
J. Biol. Chem.281:1137-1144(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGF2;MUTAGENESIS OF CYS-214
5.

"Characterization and molecular cloning of a putative binding protein for heparin-binding growth factors."
Wu D.Q. , Kan M.K. , Sato G.H. , Okamoto T. , Sato J.D.
J. Biol. Chem.266:16778-16785(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;PROTEIN SEQUENCE OF 34-67; 92-118 AND 146-158;IDENTIFICATION IN A COMPLEX WITH FGF1 AND FGF2;INTERACTION WITH FGF1;TISSUE SPECIFICITY
tissue: Epidermal carcinoma.
6.

"Gene sequence for the human FGF-binding protein HBp17."
Shi S. , Sato J.D.
Submitted (1999-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Tongue.
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Ovary.
tissue: Pancreas.
10.

"A secreted FGF-binding protein can serve as the angiogenic switch in human cancer."
Czubayko F. , Liaudet-Coopman E.D. , Aigner A. , Tuveson A.T. , Berchem G.J. , Wellstein A.
Nat. Med.3:1137-1140(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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