Fibrinogen alpha chain (Protein name
), FIBA_HUMAN from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Related Databases
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Citations (5)
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Gene name:
FGA;
Protein name:
Fibrinogen alpha chain;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
Function:
Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
Polyclonal Antibody for Human Fibrinogen alpha chain
Polyclonal Antibody for Human Fibrinogen alpha chain
Polyclonal Antibody for Human Fibrinogen alpha chain
Polyclonal Antibody for Human Fibrinogen alpha chain
Polyclonal Antibody for Human Fibrinogen alpha chain
Polyclonal Antibody for Human Fibrinogen alpha chain
Polyclonal Antibody for Human Fibrinogen alpha chain
Monoclonal Antibody for Human Fibrinogen alpha chain
Monoclonal Antibody for Human Fibrinogen alpha chain
Monoclonal Antibody for Human Fibrinogen alpha chain
Monoclonal Antibody for Human Fibrinogen alpha chain
Monoclonal Antibody for Human Fibrinogen alpha chain
Monoclonal Antibody for Human Fibrinogen alpha chain
Monoclonal Antibody for Human Fibrinogen alpha chain
Protein for Human Fibrinogen alpha chain
Protein for Human Fibrinogen alpha chain
Protein for Human Fibrinogen alpha chain
Protein for Human Fibrinogen alpha chain
Protein for Human Fibrinogen alpha chain
Protein for Human Fibrinogen alpha chain
Protein for Human Fibrinogen alpha chain
R&D Technical Data
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s
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Precision
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Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤9.1%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤12.4%
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Recovery
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Recovery was determined by spiking various levels of FIBA into serum and plasma .
Sample Type
Average(%)
Recovery Range(%)
Serum
105
96-108
Plasma
104
100-106
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Linearity
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The linearity of the kit was assayed by testing samples spiked with appropriate concentration of FIBA and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Sample
1:2
1:4
1:8
1:16
serum(n=5)
102-110%
104-112%
98-106%
96-106%
EDTA plasma(n=5)
103-108%
96-105%
98-107%
102-108%
heparin plasma(n=5)
95-110%
96-102%
101-106%
105-109%
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Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-686
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Cited for: REVIEW;ELECTRON MICROSCOPY;POLYMERIZATION;LIGANDS
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Cited for: CROSS-LINKING SITE FOR ALPHA-2-PLASMIN INHIBITOR
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-22;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-412 AND SER-609;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-686
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 130-216
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORMS 1 AND 2)
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-6; ALA-331 AND ALA-456
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT ALA-331
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
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Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 130-216
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Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 666-866;GLYCOSYLATION AT ASN-686
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Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 130-216