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Index > Protein center > FN1(Gene name) > Human
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  • FN1 (Gene name),
  • Fibronectin (Protein name ),  FINC_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    FN1(FN);
    Protein name:
    Fibronectin(FN);
    Alternative:
    Cold-insoluble globulin(CIG);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1. Interacts with FBLN7 (By similarity). Interacts with COMP. Interacts with S.aureus fnbA. Interacts with TNR; the interaction inhibits cell adhesion and neurite outgrowth (By similarity). Interacts with FST3.
    Function:
    Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    2386
    Sequence:
    50:
    MLRGPGPGLL | LLAVQCLGTA | VPSTGASKSK | RQAQQMVQPQ | SPVAVSQSKP | 
    100:
    GCYDNGKHYQ | INQQWERTYL | GNALVCTCYG | GSRGFNCESK | PEAEETCFDK | 
    150:
    YTGNTYRVGD | TYERPKDSMI | WDCTCIGAGR | GRISCTIANR | CHEGGQSYKI | 
    200:
    GDTWRRPHET | GGYMLECVCL | GNGKGEWTCK | PIAEKCFDHA | AGTSYVVGET | 
    250:
    WEKPYQGWMM | VDCTCLGEGS | GRITCTSRNR | CNDQDTRTSY | RIGDTWSKKD | 
    300:
    NRGNLLQCIC | TGNGRGEWKC | ERHTSVQTTS | SGSGPFTDVR | AAVYQPQPHP | 
    350:
    QPPPYGHCVT | DSGVVYSVGM | QWLKTQGNKQ | MLCTCLGNGV | SCQETAVTQT | 
    400:
    YGGNSNGEPC | VLPFTYNGRT | FYSCTTEGRQ | DGHLWCSTTS | NYEQDQKYSF | 
    450:
    CTDHTVLVQT | RGGNSNGALC | HFPFLYNNHN | YTDCTSEGRR | DNMKWCGTTQ | 
    500:
    NYDADQKFGF | CPMAAHEEIC | TTNEGVMYRI | GDQWDKQHDM | GHMMRCTCVG | 
    550:
    NGRGEWTCIA | YSQLRDQCIV | DDITYNVNDT | FHKRHEEGHM | LNCTCFGQGR | 
    600:
    GRWKCDPVDQ | CQDSETGTFY | QIGDSWEKYV | HGVRYQCYCY | GRGIGEWHCQ | 
    650:
    PLQTYPSSSG | PVEVFITETP | SQPNSHPIQW | NAPQPSHISK | YILRWRPKNS | 
    700:
    VGRWKEATIP | GHLNSYTIKG | LKPGVVYEGQ | LISIQQYGHQ | EVTRFDFTTT | 
    750:
    STSTPVTSNT | VTGETTPFSP | LVATSESVTE | ITASSFVVSW | VSASDTVSGF | 
    800:
    RVEYELSEEG | DEPQYLDLPS | TATSVNIPDL | LPGRKYIVNV | YQISEDGEQS | 
    850:
    LILSTSQTTA | PDAPPDTTVD | QVDDTSIVVR | WSRPQAPITG | YRIVYSPSVE | 
    900:
    GSSTELNLPE | TANSVTLSDL | QPGVQYNITI | YAVEENQEST | PVVIQQETTG | 
    950:
    TPRSDTVPSP | RDLQFVEVTD | VKVTIMWTPP | ESAVTGYRVD | VIPVNLPGEH | 
    1000:
    GQRLPISRNT | FAEVTGLSPG | VTYYFKVFAV | SHGRESKPLT | AQQTTKLDAP | 
    1050:
    TNLQFVNETD | STVLVRWTPP | RAQITGYRLT | VGLTRRGQPR | QYNVGPSVSK | 
    1100:
    YPLRNLQPAS | EYTVSLVAIK | GNQESPKATG | VFTTLQPGSS | IPPYNTEVTE | 
    1150:
    TTIVITWTPA | PRIGFKLGVR | PSQGGEAPRE | VTSDSGSIVV | SGLTPGVEYV | 
    1200:
    YTIQVLRDGQ | ERDAPIVNKV | VTPLSPPTNL | HLEANPDTGV | LTVSWERSTT | 
    1250:
    PDITGYRITT | TPTNGQQGNS | LEEVVHADQS | SCTFDNLSPG | LEYNVSVYTV | 
    1300:
    KDDKESVPIS | DTIIPAVPPP | TDLRFTNIGP | DTMRVTWAPP | PSIDLTNFLV | 
    1350:
    RYSPVKNEED | VAELSISPSD | NAVVLTNLLP | GTEYVVSVSS | VYEQHESTPL | 
    1400:
    RGRQKTGLDS | PTGIDFSDIT | ANSFTVHWIA | PRATITGYRI | RHHPEHFSGR | 
    1450:
    PREDRVPHSR | NSITLTNLTP | GTEYVVSIVA | LNGREESPLL | IGQQSTVSDV | 
    1500:
    PRDLEVVAAT | PTSLLISWDA | PAVTVRYYRI | TYGETGGNSP | VQEFTVPGSK | 
    1550:
    STATISGLKP | GVDYTITVYA | VTGRGDSPAS | SKPISINYRT | EIDKPSQMQV | 
    1600:
    TDVQDNSISV | KWLPSSSPVT | GYRVTTTPKN | GPGPTKTKTA | GPDQTEMTIE | 
    1650:
    GLQPTVEYVV | SVYAQNPSGE | SQPLVQTAVT | NIDRPKGLAF | TDVDVDSIKI | 
    1700:
    AWESPQGQVS | RYRVTYSSPE | DGIHELFPAP | DGEEDTAELQ | GLRPGSEYTV | 
    1750:
    SVVALHDDME | SQPLIGTQST | AIPAPTDLKF | TQVTPTSLSA | QWTPPNVQLT | 
    1800:
    GYRVRVTPKE | KTGPMKEINL | APDSSSVVVS | GLMVATKYEV | SVYALKDTLT | 
    1850:
    SRPAQGVVTT | LENVSPPRRA | RVTDATETTI | TISWRTKTET | ITGFQVDAVP | 
    1900:
    ANGQTPIQRT | IKPDVRSYTI | TGLQPGTDYK | IYLYTLNDNA | RSSPVVIDAS | 
    1950:
    TAIDAPSNLR | FLATTPNSLL | VSWQPPRARI | TGYIIKYEKP | GSPPREVVPR | 
    2000:
    PRPGVTEATI | TGLEPGTEYT | IYVIALKNNQ | KSEPLIGRKK | TDELPQLVTL | 
    2050:
    PHPNLHGPEI | LDVPSTVQKT | PFVTHPGYDT | GNGIQLPGTS | GQQPSVGQQM | 
    2100:
    IFEEHGFRRT | TPPTTATPIR | HRPRPYPPNV | GEEIQIGHIP | REDVDYHLYP | 
    2150:
    HGPGLNPNAS | TGQEALSQTT | ISWAPFQDTS | EYIISCHPVG | TDEEPLQFRV | 
    2200:
    PGTSTSATLT | GLTRGATYNV | IVEALKDQQR | HKVREEVVTV | GNSVNEGLNQ | 
    2250:
    PTDDSCFDPY | TVSHYAVGDE | WERMSESGFK | LLCQCLGFGS | GHFRCDSSRW | 
    2300:
    CHDNGVNYKI | GEKWDRQGEN | GQMMSCTCLG | NGKGEFKCDP | HEATCYDDGK | 
    2350:
    TYHVGEQWQK | EYLGAICSCT | CFGGQRGWRC | DNCRRPGGEP | SPEGTTGQSY | 
    2386:
    NQYSQRYHQR | TNTNVNCPIE | CFMPLDVQAD | REDSRE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human FN
    Cat.:
    E0037h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human FN
    Cat.:
    E0037m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human FN
    Cat.:
    E0037r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human FN
    Cat.:
    E0037d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human FN
    Cat.:
    E0037b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human FN
    Cat.:
    E0037c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human FN
    MSDS:
    Please sign in first.
    CLIA Kit for Human FN
    Cat.:
    U0037c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human FN
    Cat.:
    U0037b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human FN
    MSDS:
    Please sign in first.
    CLIA Kit for Human FN
    Cat.:
    U0037d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human FN
    Cat.:
    U0037r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human FN
    Cat.:
    U0037m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human FN
    Cat.:
    U0037h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human FN
    Cat.:
    P0037Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FN
    Polyclonal Antibody for Human FN
    Polyclonal Antibody for Human FN
    Cat.:
    P0037Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FN
    Cat.:
    P0037Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FN
    Polyclonal Antibody for Human FN
    Monoclonal Antibody for Human FN
    Monoclonal Antibody for Human FN
    Monoclonal Antibody for Human FN
    Monoclonal Antibody for Human FN
    Monoclonal Antibody for Human FN
    Monoclonal Antibody for Human FN
    Monoclonal Antibody for Human FN
    Protein for Human FN
    Protein for Human FN
    Protein for Human FN
    Protein for Human FN
    Protein for Human FN
    Protein for Human FN
    Protein for Human FN

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Phenotypic and genetic alterations in mammary stroma: implications for tumour progression."
      Schor S.L. , Schor A.M.
      Breast Cancer Res.3:373-379(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANTS PRO-817 AND ILE-2170
    2. 2.
      "The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3'-untranslated region-dependent nuclear sequestration of its precursor messenger RNA."
      Kay R.A. , Ellis I.R. , Jones S.J. , Perrier S. , Florence M.M. , Schor A.M. , Schor S.L.
      Cancer Res.65:10742-10749(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 16)
    3. 3.
      "Vector-capping: a simple method for preparing a high-quality full-length cDNA library."
      Kato S. , Ohtoko K. , Ohtake H. , Kimura T.
      DNA Res.12:53-62(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 14);VARIANTS PRO-817 AND ILE-2170
      tissue: Retinal pigment epithelium.
    4. 4.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 14);VARIANTS LEU-15; PRO-817 AND ILE-2170
      tissue: Aortic endothelium.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 7; 8; 9; 10; 13; 14; 15 AND 16);VARIANTS LEU-15; PRO-817 AND ILE-2170
      tissue: Amygdala.
      tissue: Cervix.
      tissue: Endometrial tumor.
      tissue: Uterine endothelium.
    6. 6.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 10);VARIANTS LEU-15; PRO-817 AND ILE-2170
      tissue: Cerebellum.
    9. 9.
      "Human fibronectin is synthesized as a pre-propolypeptide."
      Gutman A. , Yamada K.M. , Kornblihtt A.R.
      FEBS Lett.207:145-148(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-38
    10. 10.
      "Cloning and analysis of the promotor region of the human fibronectin gene."
      Dean D.C. , Bowlus C.L. , Bourgeois S.
      Proc. Natl. Acad. Sci. U.S.A.84:1876-1880(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-49;VARIANT LEU-15
    11. 11.
      "Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene."
      Kornblihtt A.R. , Umezawa K. , Vibe-Pedersen K. , Baralle F.E.
      EMBO J.4:1755-1759(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 28-2386 (ISOFORM 3);VARIANTS PRO-817 AND ILE-2170
    12. 12.
      "Primary structure of human plasma fibronectin. The 29,000-dalton NH2-terminal domain."
      Garcia-Pardo A. , Pearlstein E. , Frangione B.
      J. Biol. Chem.258:12670-12674(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-290;PYROGLUTAMATE FORMATION AT GLN-32
    13. 13.
      Godfrey H.P. , Ebrahim A.A.
      Submitted (1995-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 103-481 (ISOFORMS 1/3/4/5/6/7/8/9/10/11/12/13/14/15);NUCLEOTIDE SEQUENCE [MRNA] OF 1116-1422 (ISOFORMS 1/3/4/5/6/8/9/10/14);NUCLEOTIDE SEQUENCE [MRNA] OF 1238-2160 (ISOFORMS 9 AND 12);NUCLEOTIDE SEQUENCE [MRNA] OF 1449-1825 (ISOFORMS 8/9/10/13/14);NUCLEOTIDE SEQUENCE [MRNA] OF 1919-2161 (ISOFORMS 3/7/14);NUCLEOTIDE SEQUENCE [MRNA] OF 2228-2386 (ISOFORMS 1/3/6/7/8/9/10/11/12/13/14/15)
      tissue: Peripheral blood T-cell.
      tissue: Umbilical vein endothelial cell.
    14. 14.
      "Mapping the collagen-binding site of human fibronectin by expression in Escherichia coli."
      Owens R.J. , Baralle F.E.
      EMBO J.5:2825-2830(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 309-608;COLLAGEN-BINDING
    15. 15.
      "Primary structure of a DNA- and heparin-binding domain (Domain III) in human plasma fibronectin."
      Calaycay J. , Pande H. , Lee T. , Borsi L. , Siri A. , Shively J.E. , Zardi L.
      J. Biol. Chem.260:12136-12141(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 616-705
    16. 16.
      "Identification of novel fibronectin fragments detected specifically in juvenile urine."
      Iida R. , Yasuda T. , Kishi K.
      FEBS J.274:3939-3947(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 723-911;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;GLYCOSYLATION AT ASN-877;VARIANT PRO-817
      tissue: Urine.
    17. 17.
      "Human fibronectin: cell specific alternative mRNA splicing generates polypeptide chains differing in the number of internal repeats."
      Kornblihtt A.R. , Vibe-Pedersen K. , Baralle F.E.
      Nucleic Acids Res.12:5853-5868(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 973-2386 (ISOFORM 3);VARIANT ILE-2170
    18. 18.
      "Sequence analysis and in vivo expression show that alternative splicing of ED-B and ED-A regions of the human fibronectin gene are independent events."
      Paolella G. , Henchcliffe C. , Sebastio G. , Baralle F.E.
      Nucleic Acids Res.16:3545-3557(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1232-1782 (ISOFORMS 7/15)
    19. 19.
      "Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon."
      Zardi L. , Carnemolla B. , Siri A. , Petersen T.E. , Paolella G. , Sebastio G. , Baralle F.E.
      EMBO J.6:2337-2342(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1234-1286 (ISOFORM 7)
    20. 20.
      "Identification of a third region of cell-specific alternative splicing in human fibronectin mRNA."
      Gutman A. , Kornblihtt A.R.
      Proc. Natl. Acad. Sci. U.S.A.84:7179-7182(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1257-1365 (ISOFORM 11)
    21. 21.
      "The cell attachment domain of fibronectin. Determination of the primary structure."
      Pierschbacher M.D. , Ruoslahti E. , Sundelin J. , Lind P. , Peterson P.A.
      J. Biol. Chem.257:9593-9597(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1441-1548
    22. 22.
      "Molecular cloning and nucleotide sequence of a cDNA clone coding for the cell attachment domain in human fibronectin."
      Oldberg A. , Linney E. , Ruoslahti E.
      J. Biol. Chem.258:10193-10196(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1448-1540
    23. 23.
      "Evolution of the fibronectin gene. Exon structure of cell attachment domain."
      Oldberg A. , Ruoslahti E.
      J. Biol. Chem.261:2113-2116(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1448-1540
    24. 24.
      "Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneity."
      Garcia-Pardo A. , Rostagno A. , Frangione B.
      Biochem. J.241:923-928(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1589-2058
    25. 25.
      "Human cellular fibronectin: comparison of the carboxyl-terminal portion with rat identifies primary structural domains separated by hypervariable regions."
      Bernard M.P. , Kolbe M. , Weil D. , Chu M.-L.
      Biochemistry24:2698-2704(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1594-2386 (ISOFORMS 1/11/15);VARIANT ILE-2170
    26. 26.
      "Human plasma fibronectin. Demonstration of structural differences between the A- and B-chains in the III CS region."
      Tressel T. , McCarthy J.B. , Calaycay J. , Lee T.D. , Legesse K. , Shively J.E. , Pande H.
      Biochem. J.274:731-738(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1614-1623; 1730-1748; 1756-1759; 1803-1811; 1860-1923; 1930-1945; 1949-1972; 1982-1989; 1991-2003; 2020-2038; 2060-2131; 2150-2180; 2185-2205 AND 2231-2242;GLYCOSYLATION AT THR-2064 AND THR-2065;LACK OF GLYCOSYLATION AT ASN-2108;VARIANT ILE-2170;IDENTIFICATION BY MASS SPECTROMETRY
    27. 27.
      "Human fibronectin: molecular cloning evidence for two mRNA species differing by an internal segment coding for a structural domain."
      Kornblihtt A.R. , Vibe-Pedersen K. , Baralle F.E.
      EMBO J.3:221-226(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1624-1727 (ISOFORMS 8/9/10/12/13/14)
    28. 28.
      "Human liver fibronectin complementary DNAs: identification of two different messenger RNAs possibly encoding the alpha and beta subunits of plasma fibronectin."
      Sekiguchi K. , Klos A.M. , Kurachi K. , Yoshitake S. , Hakomori S.
      Biochemistry25:4936-4941(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1712-1739 (ISOFORMS 1/3/4/5/6/7/11/15)
    29. 29.
      "Novel cartilage-specific splice variants of fibronectin."
      Parker A.E. , Boutell J. , Carr A. , Maciewicz R.A.
      Osteoarthritis Cartilage10:528-534(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1788-2386 (ISOFORMS 4; 5 AND 6);VARIANT ILE-2170
      tissue: Cartilage.
    30. 30.
      "Isolation and characterization of cDNA clones for human liver fibronectin."
      Umezawa K. , Kornblihtt A.R. , Baralle F.E.
      FEBS Lett.186:31-34(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1948-2067 (ISOFORMS 1/8/10/11/15)
    31. 31.
      "Donor and acceptor splice signals within an exon of the human fibronectin gene: a new type of differential splicing."
      Vibe-Pedersen K. , Magnusson S. , Baralle F.E.
      FEBS Lett.207:287-291(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1992-2147
    32. 32.
      "Primary structure of human plasma fibronectin. Characterization of a 31,000-dalton fragment from the COOH-terminal region containing a free sulfhydryl group and a fibrin-binding site."
      Garcia-Pardo A. , Pearlstein E. , Frangione B.
      J. Biol. Chem.260:10320-10325(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2071-2356 (ISOFORM 3);VARIANT ILE-2170
    33. 33.
      "Isolation and characterization of cDNA clones for human and bovine fibronectins."
      Kornblihtt A.R. , Vibe-Pedersen K. , Baralle F.E.
      Proc. Natl. Acad. Sci. U.S.A.80:3218-3222(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2291-2386
    34. 34.
      "Tyrosine sulfation of proteins from the human hepatoma cell line HepG2."
      Liu M.C. , Yu S. , Sy J. , Redman C.M. , Lipmann F.
      Proc. Natl. Acad. Sci. U.S.A.82:7160-7164(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SULFATION
    35. 35.
      "Purification of a young age-related glycoprotein (Ugl-Y) from normal human urine."
      Iida R. , Yasuda T. , Kishi K.
      J. Biochem.101:357-363(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF UGL-Y1;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;GLYCOSYLATION
    36. 36.
      "Fibulin binds to itself and to the carboxyl-terminal heparin-binding region of fibronectin."
      Balbona K. , Tran H. , Godyna S. , Ingham K.C. , Strickland D.K. , Argraves W.S.
      J. Biol. Chem.267:20120-20125(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FBLN1
    37. 37.
      "Further characterization of the NH2-terminal fibrin-binding site on fibronectin."
      Rostagno A. , Williams M.J. , Baron M. , Campbell I.D. , Gold L.I.
      J. Biol. Chem.269:31938-31945(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF FIBRIN-BINDING SITE 1
    38. 38.
      "Superfibronectin is a functionally distinct form of fibronectin."
      Morla A. , Zhang Z. , Ruoslahti E.
      Nature367:193-196(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;FUNCTION OF ANASTELLIN
    39. 39.
      "Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin."
      Sasaki T. , Brakebusch C. , Engel J. , Timpl R.
      EMBO J.17:1606-1613(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LGALS3BP
    40. 40.
      "A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis."
      Yi M. , Ruoslahti E.
      Proc. Natl. Acad. Sci. U.S.A.98:620-624(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF ANASTELLIN
    41. 41.
      "The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin."
      Tu H. , Sasaki T. , Snellman A. , Gohring W. , Pirila P. , Timpl R. , Pihlajaniemi T.
      J. Biol. Chem.277:23092-23099(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COL13A1
    42. 42.
      "Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin."
      Di Cesare P.E. , Chen F.S. , Moergelin M. , Carlson C.S. , Leslie M.P. , Perris R. , Fang C.
      Matrix Biol.21:461-470(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COMP
    43. 43.
      "In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin."
      Filla M.S. , Liu X. , Nguyen T.D. , Polansky J.R. , Brandt C.R. , Kaufman P.L. , Peters D.M.
      Invest. Ophthalmol. Vis. Sci.43:151-161(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MYOC
    44. 44.
      "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
      Bunkenborg J. , Pilch B.J. , Podtelejnikov A.V. , Wisniewski J.R.
      Proteomics4:454-465(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-528
      tissue: Plasma.
    45. 45.
      "Anastellin, a fragment of the first type III repeat of fibronectin, inhibits extracellular signal-regulated kinase and causes G(1) arrest in human microvessel endothelial cells."
      Ambesi A. , Klein R.M. , Pumiglia K.M. , McKeown-Longo P.J.
      Cancer Res.65:148-156(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF ANASTELLIN
    46. 46.
      "Differential analysis of site-specific glycans on plasma and cellular fibronectins: application of a hydrophilic affinity method for glycopeptide enrichment."
      Tajiri M. , Yoshida S. , Wada Y.
      Glycobiology15:1332-1340(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-279; ASN-430; ASN-528; ASN-542; ASN-877; ASN-1007; ASN-1244 AND ASN-2108
    47. 47.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-430; ASN-528; ASN-542; ASN-1007 AND ASN-1244
      tissue: Plasma.
    48. 48.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2384;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    49. 49.
      "A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin."
      Maguer-Satta V. , Forissier S. , Bartholin L. , Martel S. , Jeanpierre S. , Bachelard E. , Rimokh R.
      Exp. Cell Res.312:434-442(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FST3
    50. 50.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2384;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    51. 51.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-528 AND ASN-1007
      tissue: Liver.
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      "A strategy for precise and large scale identification of core fucosylated glycoproteins."
      Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
      Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-528; ASN-542 AND ASN-1007
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      You R. , Klein R.M. , Zheng M. , McKeown-Longo P.J.
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF ANASTELLIN;MUTAGENESIS OF LEU-663 AND TYR-666
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      Baron M. , Main A.L. , Driscoll P.C. , Mardon H.J. , Boyd J. , Campbell I.D.
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      Sticht H. , Pickford A.R. , Potts J.R. , Campbell I.D.
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      Structure7:381-390(1999) [PubMed] [Europe PMC] [Abstract]
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      Bocquier A.A. , Potts J.R. , Pickford A.R. , Campbell I.D.
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      Nature423:177-181(2003) [PubMed] [Europe PMC] [Abstract]
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      Dickinson C.D. , Veerapandian B. , Dai X.-P. , Hamlin R.C. , Xuong N.-H. , Ruoslahti E. , Ely K.R.
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      Vakonakis I. , Staunton D. , Rooney L.M. , Campbell I.D.
      EMBO J.26:2575-2583(2007) [PubMed] [Europe PMC] [Abstract]
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      "The solution and crystal structures of a module pair from the Staphylococcus aureus-binding site of human fibronectin -- a tale with a twist."
      Rudino-Pinera E. , Ravelli R.B. , Sheldrick G.M. , Nanao M.H. , Korostelev V.V. , Werner J.M. , Schwarz-Linek U. , Potts J.R. , Garman E.F.
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 93-182;X-RAY CRYSTALLOGRAPHY (1.2 ANGSTROMS) OF 93-182;DISULFIDE BONDS
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      "Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains."
      Bingham R.J. , Rudino-Pinera E. , Meenan N.A.G. , Schwarz-Linek U. , Turkenburg J.P. , Hoeoek M. , Garman E.F. , Potts J.R.
      Proc. Natl. Acad. Sci. U.S.A.105:12254-12258(2008) [PubMed] [Europe PMC] [Abstract]
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      "Solution structure of the 11th FN1 domain from human fibronectin 1."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2008-03) to the PDB data bank
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      "Identification and structural analysis of type I collagen sites in complex with fibronectin fragments."
      Erat M.C. , Slatter D.A. , Lowe E.D. , Millard C.J. , Farndale R.W. , Campbell I.D. , Vakonakis I.
      Proc. Natl. Acad. Sci. U.S.A.106:4195-4200(2009) [PubMed] [Europe PMC] [Abstract]
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ASN-940; PRO-1120 AND ASN-2380
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GFND2 CYS-973; ARG-1834 AND ARG-1883;VARIANTS LEU-15 AND VAL-1960;CHARACTERIZATION OF VARIANTS GFND2 ARG-1834 AND ARG-1883
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ILE-2170;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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