Protein name:
Ferritin light chain (Ferritin L subunit) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited. Iron enters the spherical protein shell through pores that are formed between subunits. Mutations leading to truncation or the addition of extra residues at the C-terminus interfere with normal pore formation and with iron accumulation.
Function:
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Protein Attributes:
50:
MSSQIRQNYS | TDVEAAVNSL | VNLYLQASYT | YLSLGFYFDR | DDVALEGVSH |
100:
FFRELAEEKR | EGYERLLKMQ | NQRGGRALFQ | DIKKPAEDEW | GKTPDAMKAA |
150:
MALEKKLNQA | LLDLHALGSA | RTDPHLCDFL | ETHFLDEEVK | LIKKMGDHLT |
175:
NLHRLGGPEA | GLGEYLFERL | TLKHD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Dog
Pig
Rabbit
Bovine
ELISA Kit for Human Ferritin L subunit
ELISA Kit for Human Ferritin L subunit
ELISA Kit for Human Ferritin L subunit
ELISA Kit for Human Ferritin L subunit
ELISA Kit for Human Ferritin L subunit
CLIA Kit for Human Ferritin L subunit
CLIA Kit for Human Ferritin L subunit
CLIA Kit for Human Ferritin L subunit
CLIA Kit for Human Ferritin L subunit
CLIA Kit for Human Ferritin L subunit
Polyclonal Antibody for Human Ferritin L subunit
Polyclonal Antibody for Human Ferritin L subunit
Polyclonal Antibody for Human Ferritin L subunit
Polyclonal Antibody for Human Ferritin L subunit
Polyclonal Antibody for Human Ferritin L subunit
Monoclonal Antibody for Human Ferritin L subunit
Monoclonal Antibody for Human Ferritin L subunit
Monoclonal Antibody for Human Ferritin L subunit
Monoclonal Antibody for Human Ferritin L subunit
Monoclonal Antibody for Human Ferritin L subunit
Protein for Human Ferritin L subunit
Protein for Human Ferritin L subunit
Protein for Human Ferritin L subunit
Protein for Human Ferritin L subunit
Protein for Human Ferritin L subunit
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Colon endothelium .
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
tissue :
Skin .
tissue :
Testis .
tissue :
Urinary bladder .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-36 AND 41-175;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT SER-2
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Liver .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 84-90 AND 145-155
tissue :
Placenta .
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 2-174;SUBUNIT
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.85 ANGSTROMS) OF 1-191;FUNCTION;SUBUNIT;DOMAIN
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J. Biol. Chem.285:11948-11957(2010)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 1-166;FUNCTION;SUBUNIT;DOMAIN;FUNCTION AS A FERROXIDASE;IDENTIFICATION BY MASS SPECTROMETRY;ROLE IN DISEASE
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT NBIA3 THR-96
19.
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Haematologica94:335-339(2009)
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HHCS ILE-30