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Index > Protein center > FUT6(Gene name) > Human
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  • FUT6 (Gene name),
  • Alpha-(1,3)-fucosyltransferase (Protein name ),  FUT6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FUT6(FCT3A);
    Protein name:
    Alpha-(1,3)-fucosyltransferase;
    Alternative:
    Fucosyltransferase VI(Fuc-TVI;FucT-VI);Fucosyltransferase 6;Galactoside 3-L-fucosyltransferase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP-beta-fucose to alpha-2,3 sialylated substrates.
    Subcellular Location:
    Golgi apparatus Golgi stack membrane Single-pass type II membrane protein Membrane-bound form in trans cisternae of Golgi.
    Protein Attributes:
    Sequence length:
    359
    Sequence:
    50:
    MDPLGPAKPQ | WSWRCCLTTL | LFQLLMAVCF | FSYLRVSQDD | PTVYPNGSRF | 
    100:
    PDSTGTPAHS | IPLILLWTWP | FNKPIALPRC | SEMVPGTADC | NITADRKVYP | 
    150:
    QADAVIVHHR | EVMYNPSAQL | PRSPRRQGQR | WIWFSMESPS | HCWQLKAMDG | 
    200:
    YFNLTMSYRS | DSDIFTPYGW | LEPWSGQPAH | PPLNLSAKTE | LVAWAVSNWG | 
    250:
    PNSARVRYYQ | SLQAHLKVDV | YGRSHKPLPQ | GTMMETLSRY | KFYLAFENSL | 
    300:
    HPDYITEKLW | RNALEAWAVP | VVLGPSRSNY | ERFLPPDAFI | HVDDFQSPKD | 
    350:
    LARYLQELDK | DHARYLSYFR | WRETLRPRSF | SWALAFCKAC | WKLQEESRYQ | 
    359:
    TRGIAAWFT
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-(1,3)-fucosyltransferase
    Cat.:
    E0358h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Alpha-(1,3)-fucosyltransferase
    Cat.:
    U0358h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    Polyclonal Antibody for Human Alpha-(1,3)-fucosyltransferase
    Cat.:
    P0358Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Alpha-(1,3)-fucosyltransferase
    Protein for Human Alpha-(1,3)-fucosyltransferase

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The cloning and expression of a human alpha-1,3 fucosyltransferase capable of forming the E-selectin ligand."
      Koszdin K.L. , Bowen B.R.
      Biochem. Biophys. Res. Commun.187:152-157(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes."
      Weston B.W. , Smith P.L. , Kelly R.J. , Lowe J.B.
      J. Biol. Chem.267:24575-24584(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    3. 3.
      "Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms."
      Cameron H.S. , Szczepaniak D. , Weston B.W.
      J. Biol. Chem.270:20112-20122(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Kidney.
    4. 4.
      "Isolation and expression of human alpha-(1,3)-fucosyltransferase."
      Rahim I. , Schmidt L.R. , Wahl D. , Drayson E. , Maslanik W. , Stranahan P.L. , Pettijohn D.E.
      Submitted (1999-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT SER-124
      tissue: Squamous cell carcinoma.
    5. 5.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6)."
      Mollicone R. , Reguigne I. , Fletcher A. , Aziz A. , Rustam M. , Weston B.W. , Kelly R.J. , Lowe J.B. , Oriol R.
      J. Biol. Chem.269:12662-12671(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POLYMORPHISM;VARIANT LYS-247;CHARACTERIZATION OF VARIANT LYS-247
    8. 8.
      "Identification of two functionally deficient plasma alpha 3-fucosyltransferase (FUT6) alleles."
      Elmgren A. , Borjeson C. , Mollicone R. , Oriol R. , Fletcher A. , Larson G.
      Hum. Mutat.16:473-481(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SER-124; VAL-244; LYS-247 AND GLY-303;CHARACTERIZATION OF VARIANTS SER-124; VAL-244; LYS-247 AND GLY-303
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