GALNS ELISA Kit for Human(Homo sapiens) | EIAab.comGALNS ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > GALNS(Gene name) > Human

GALNS (Gene name),

N-acetylgalactosamine-6-sulfatase (Protein name ), GALNS_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

GALNS;

Protein name:

N-acetylgalactosamine-6-sulfatase;

Alternative:

Galactose-6-sulfate sulfatase(GalN6S);Chondroitinsulfatase(Chondroitinase);N-acetylgalactosamine-6-sulfate sulfatase(GalNAc6S sulfatase);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Oligomer of disulfide linked 40- and 15 kDa polypeptides.

Function:

N/A

Subcellular Location:

Lysosome

Protein Attributes:

Sequence length:

522

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

522:

CEKLGKCLTP | PESIPKKCLW | SH

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Hs.271383

SMR:

P34059

MIM:

253000

Pfam:

PF00884

STRING:

9606.ENSP00000268695

String:

P34059

KEGG:

hsa:2588

Uniprot:

P34059

FOR

ELISA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

E0205d

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

E0205h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

E0205p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

E0205m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

E0205r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

U0205d

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

U0205r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

U0205p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

U0205h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human N-acetylgalactosamine-6-sulfatase

Cat.:

U0205m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human N-acetylgalactosamine-6-sulfatase

Cat.:

P0205Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human N-acetylgalactosamine-6-sulfatase

Cat.:

P0205Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human N-acetylgalactosamine-6-sulfatase

Cat.:

P0205Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human N-acetylgalactosamine-6-sulfatase

Monoclonal Antibody for Human N-acetylgalactosamine-6-sulfatase

Protein for Human N-acetylgalactosamine-6-sulfatase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Morquio disease: isolation, characterization and expression of full-length cDNA for human N-acetylgalactosamine-6-sulfate sulfatase."
Tomatsu S. , Fukuda S. , Masue M. , Sukegawa K. , Fukao T. , Yamagishi A. , Hori T. , Iwata H. , Ogawa T. , Nakashima Y. , Hanyu Y. , Hashimoto T. , Titani K. , Oyama R. , Suzuki M. , Yagi K. , Hayashi Y. , Orii T.
Biochem. Biophys. Res. Commun.181:677-683(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];PARTIAL PROTEIN SEQUENCE
tissue: Placenta.
2.

"Morquio A syndrome: cloning, sequence, and structure of the human N-acetylgalactosamine 6-sulfatase (GALNS) gene."
Morris C.P. , Guo X.H. , Apostolou S. , Hopwood J.J. , Scott H.S.
Genomics22:652-654(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
4.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-423
tissue: Liver.
5.

"The structure of human GALNS reveals the molecular basis for mucopolysaccharidosis IV A."
Rivera-Colon Y. , Schutsky E.K. , Kita A.Z. , Garman S.C.
J. Mol. Biol.423:736-751(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 27-522;GLYCOSYLATION AT ASN-204 AND ASN-423;OXOALANINE AT CYS-79;SUBUNIT;COFACTOR;CATALYTIC ACTIVITY;CALCIUM-BINDING SITES;DISULFIDE BONDS
6.

"Mucopolysaccharidosis type IVA. N-acetylgalactosamine-6-sulfate sulfatase exonic point mutations in classical Morquio and mild cases."
Fukuda S. , Tomatsu S. , Masue M. , Sukegawa K. , Iwata H. , Ogawa T. , Nakashima Y. , Hori T. , Yamagishi A. , Hanyu Y. , Morooka K. , Kiman T. , Hashimoto T. , Orii T.
J. Clin. Invest.90:1049-1053(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MPS4A;VARIANT MPS4A LYS-204
7.

"Mucopolysaccharidosis IVA: identification of a common missense mutation I113F in the N-Acetylgalactosamine-6-sulfate sulfatase gene."
Tomatsu S. , Fukuda S. , Cooper A. , Wraith J.E. , Maruf Rezvi G. , Yamagishi A. , Yamada N. , Kato Z. , Isogai K. , Sukegawa K. , Kondo N. , Suzuki Y. , Shimozawa N. , Orii T.
Am. J. Hum. Genet.57:556-563(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A ARG-77; TRP-90; VAL-96; PHE-113; LEU-151; GLY-230; THR-291; CYS-386 AND SER-487
8.

"Mucopolysaccharidosis IVA: screening and identification of mutations of the N-acetylgalactosamine-6-sulfate sulfatase gene."
Ogawa T. , Tomatsu S. , Fukuda S. , Yamagishi A. , Maruf Rezvi G. , Sukegawa K. , Kondo N. , Suzuki Y. , Shimozawa N. , Orii T.
Hum. Mol. Genet.4:341-349(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A
9.

"Mucopolysaccharidosis type IVA: identification of six novel mutations among non-Japanese patients."
Tomatsu S. , Fukuda S. , Cooper A. , Wraith J.E. , Maruf Rezvi G. , Yamagishi A. , Yamada N. , Kato Z. , Isogai K. , Sukegawa K. , Kondo N. , Suzuki Y. , Shimozawa N. , Orii T.
Hum. Mol. Genet.4:741-743(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A ARG-77; TRP-90; VAL-96; LEU-151; GLY-230 AND THR-291
10.

"Two new mutations, Q473X and N487S, in a Caucasian patient with mucopolysaccharidosis IVA (Morquio disease)."
Tomatsu S. , Fukuda S. , Cooper A. , Wraith J.E. , Yamada N. , Isogai K. , Kato Z. , Sukegawa K. , Kondo N. , Suzuki Y. , Shimozawa N. , Orii T.
Hum. Mutat.6:195-196(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MPS4A SER-487
11.

"Mucopolysaccharidosis IVA: four new exonic mutations in patients with N-acetylgalactosamine-6-sulfate sulfatase deficiency."
Tomatsu S. , Fukuda S. , Yamagishi A. , Cooper A. , Wraith J.E. , Hori T. , Kato Z. , Yamada N. , Isogai K. , Sukegawa K. , Kondo N. , Suzuki Y. , Shimozawa N. , Orii T.
Am. J. Hum. Genet.58:950-962(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A ALA-138; SER-151 AND LEU-151
12.

"Heteroallelic missense mutations of the galactosamine-6-sulfate sulfatase (GALNS) gene in a mild form of Morquio disease (MPS IVA)."
Cole D.E.C. , Fukuda S. , Gordon B.A. , Rip J.W. , Lecouteur A.N. , Rupar C.A. , Tomatsu S. , Ogawa T. , Sukegawa K. , Orii T.
Am. J. Med. Genet.63:558-565(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A CYS-94 AND VAL-97
13.

"Identification of 31 novel mutations in the N-acetylgalactosamine-6-sulfatase gene reveals excessive allelic heterogeneity among patients with Morquio A syndrome."
Bunge S. , Kleijer W.J. , Tylki-Szymanska A. , Steglich C. , Beck M. , Tomatsu S. , Fukuda S. , Poorthuis B.J.H.M. , Czartoryska B. , Orii T. , Gal A.
Hum. Mutat.10:223-232(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A
14.

"Fourteen novel mucopolysaccharidosis IVA producing mutations in GALNS gene."
Tomatsu S. , Fukuda S. , Cooper A. , Wraith J.E. , Ferreira P. , di Natale P. , Tortora P. , Fujimoto A. , Kato Z. , Yamada N. , Isogai K. , Yamagishi A. , Sukegawa K. , Suzuki Y. , Shimozawa N. , Kondo N. , Sly W.S. , Orii T.
Hum. Mutat.10:368-375(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A LEU-80; CYS-94; VAL-97; LEU-125; SER-139; GLN-166; GLY-185; SER-290; ARG-309; VAL-351; CYS-386; VAL-391 AND PRO-395
15.

"Molecular heterogeneity in mucopolysaccharidosis IVA in Australia and Northern Ireland: nine novel mutations including T312S, a common allele that confers a mild phenotype."
Yamada N. , Fukuda S. , Tomatsu S. , Muller V. , Hopwood J.J. , Nelson J. , Kato Z. , Yamagishi A. , Sukegawa K. , Kondo N. , Orii T.
Hum. Mutat.11:202-208(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A VAL-96; PHE-113; ARG-135; CYS-156; LEU-179; THR-257; VAL-284; SER-312; GLN-376 AND VAL-395
16.

"Fifteen polymorphisms in the N-acetylgalactosamine-6-sulfate sulfatase (GALNS) gene: diagnostic implications in Morquio disease."
Tomatsu S. , Fukuda S. , Cooper A. , Wraith J.E. , Yamagishi A. , Kato Z. , Yamada N. , Isogai K. , Sukegawa K. , Suzuki Y. , Shimozawa N. , Kondo N. , Orii T.
Hum. Mutat. Suppl.1:S42-S46(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SER-393 AND MET-488
17.

"Mutation and polymorphism spectrum of the GALNS gene in mucopolysaccharidosis IVA (Morquio A)."
Tomatsu S. , Montano A.M. , Nishioka T. , Gutierrez M.A. , Pena O.M. , Tranda Firescu G.G. , Lopez P. , Yamaguchi S. , Noguchi A. , Orii T.
Hum. Mutat.26:500-512(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A MET-15; 17-LEU-SER-18 DEL; ARG-23; PRO-36; LEU-41; GLU-42; 52-PRO--GLU-55 DEL; PHE-53; TRP-61; VAL-69; 71-ASN--SER-74 DELINS THR; TYR-79; LEU-94; THR-107; SER-116; CYS-141; TYR-150; GLU-155; PHE-162; THR-164; VAL-167; ALA-171; SER-179; VAL-203; ASN-233; PHE-239; TRP-253; ASP-260; PHE-285 DEL; PRO-307; ASN-310; CYS-325; ASP-340; ARG-341; PRO-345; PRO-352; LEU-357; PRO-369; THR-380; SER-380; HIS-386; ASN-388; VAL-392; ASP-398; TYR-401; 403-TRP-THR-404 DEL; ILE-452; PRO-470 AND SER-484;VARIANTS MET-67; VAL-178; MET-200; GLY-231; SER-393; VAL-459 AND MET-488
18.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] TRP-61 AND THR-510
19.

"Molecular testing of 163 patients with Morquio A (Mucopolysaccharidosis IVA) identifies 39 novel GALNS mutations."
Morrone A. , Tylee K.L. , Al-Sayed M. , Brusius-Facchin A.C. , Caciotti A. , Church H.J. , Coll M.J. , Davidson K. , Fietz M.J. , Gort L. , Hegde M. , Kubaski F. , Lacerda L. , Laranjeira F. , Leistner-Segal S. , Mooney S. , Pajares S. , Pollard L. , more...
Mol. Genet. Metab.112:160-170(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS4A GLU-16; ARG-36; ASN-40; GLY-48; LYS-51; ARG-77; LEU-80; LEU-81; GLU-84; TRP-90; PRO-91; CYS-94; LEU-94; PHE-113; VAL-116; SER-116; SER-139; ARG-141; TYR-145; LEU-151; ARG-155; LEU-156; ARG-166; SER-179; GLU-201; PRO-214; SER-216; GLY-230; ASN-233; LYS-235; THR-264; LEU-287; THR-291; CYS-301; SER-312; ARG-318; LEU-357; GLY-380; THR-380; CYS-386; HIS-386; VAL-391; VAL-392; HIS-407; VAL-415; THR-416; ARG-420; THR-492; VAL-494; SER-500 AND PHE-507;VARIANTS PHE-74; ASP-121; CYS-159; TYR-165; GLN-251; CYS-254; LYS-260 AND LYS-495;CHARACTERIZATION OF VARIANTS MPS4A GLU-16; ARG-36; LYS-51; LEU-81; GLU-84; PRO-91; VAL-116; TYR-145; LEU-156; ARG-166; GLU-201; PRO-214; SER-216; THR-264; GLY-380; VAL-415; THR-416; ARG-420; THR-492 AND SER-500

Product Feedback Wall

* Email:
*Comments: