Gata4 ELISA Kit for Mouse(Mus musculus) | EIAab.comGata4 ELISA Kit for Mouse(Mus musculus)

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Gata4 (Gene name),

Transcription factor GATA-4 (Protein name ), GATA4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gata4(Gata-4);

Protein name:

Transcription factor GATA-4;

Alternative:

GATA-binding factor 4;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with ZNF260 (By similarity). Interacts with the homeobox domain of NKX2-5 through its C-terminal zinc finger. Also interacts with JARID2 which represses its ability to activate transcription of ANF. Interacts with NFATC4 and LMCD1. Forms a complex made of CDK9, CCNT1/cyclin-T1, EP300 and GATA4 that stimulates hypertrophy in cardiomyocytes.

Function:

Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Regulates the expression of the HSP47/J6 gene in F9 cells. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

440

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

440:

SKLSPQGYAS | PVTQTSQASS | KQDSWNSLVL | ADSHGDIITA |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.247669

Pfam:

PF00320

KEGG:

mmu:14463

String:

Q08369

SMR:

Q08369

Uniprot:

Q08369

FOR

ELISA Kit for Mouse Transcription factor GATA-4

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E0374h

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ELISA Kit for Mouse Transcription factor GATA-4

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E0374c

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96T

ELISA Kit for Mouse Transcription factor GATA-4

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E0374m

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96T

ELISA Kit for Mouse Transcription factor GATA-4

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E0374r

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96T

ELISA Kit for Mouse Transcription factor GATA-4

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E0374d

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96T

CLIA Kit for Mouse Transcription factor GATA-4

Cat.:

U0374c

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96T

CLIA Kit for Mouse Transcription factor GATA-4

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U0374r

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96T

CLIA Kit for Mouse Transcription factor GATA-4

Cat.:

U0374h

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MSDS:

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96T

CLIA Kit for Mouse Transcription factor GATA-4

Cat.:

U0374m

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96T

CLIA Kit for Mouse Transcription factor GATA-4

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U0374d

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Polyclonal Antibody for Mouse Transcription factor GATA-4

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P0374Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Transcription factor GATA-4

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P0374Rb-m

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Polyclonal Antibody for Mouse Transcription factor GATA-4

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P0374Rb-r

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Polyclonal Antibody for Mouse Transcription factor GATA-4

Monoclonal Antibody for Mouse Transcription factor GATA-4

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M0374h

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40ug

Monoclonal Antibody for Mouse Transcription factor GATA-4

Cat.:

M0374m

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40ug

Monoclonal Antibody for Mouse Transcription factor GATA-4

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M0374r

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Monoclonal Antibody for Mouse Transcription factor GATA-4

Protein for Mouse Transcription factor GATA-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart."
Arceci R.J. , King A.A. , Simon M.C. , Orkin S.H. , Wilson D.B.
Mol. Cell. Biol.13:2235-2246(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut."
Laverriere A.C. , Macneill C. , Mueller C. , Poelmann R.E. , Burch J.B.E. , Evans T.
J. Biol. Chem.269:23177-23184(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF PROBABLE FRAMESHIFTS
3.

"Murine GATA-4 is expressed in heart and gut tissues."
Morrisey E.E. , Parmacek M.S.
Submitted (1997-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

Katsuoka F. , Motohashi H. , Yamamoto M.
Submitted (1999-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6 X DBA/2.
tissue: Heart.
5.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
6.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
8.

"Regulation of J6 gene expression by transcription factor GATA-4."
Bielinska M. , Wilson D.B.
Biochem. J.307:183-189(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
9.

"A calcineurin-dependent transcriptional pathway for cardiac hypertrophy."
Molkentin J.D. , Lu J.-R. , Antos C.L. , Markham B. , Richardson J. , Robbins J. , Grant S.R. , Olson E.N.
Cell93:215-228(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NFATC4
10.

"The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression."
Lee Y. , Shioi T. , Kasahara H. , Jobe S.M. , Wiese R.J. , Markham B.E. , Izumo S.
Mol. Cell. Biol.18:3120-3129(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH NKX2-5
11.

"Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors."
Kim T.-G. , Chen J. , Sadoshima J. , Lee Y.
Mol. Cell. Biol.24:10151-10160(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH JARID2
12.

"LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding."
Rath N. , Wang Z. , Lu M.M. , Morrisey E.E.
Mol. Cell. Biol.25:8864-8873(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LMCD1
13.

"Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors."
Farin H.F. , Bussen M. , Schmidt M.K. , Singh M.K. , Schuster-Gossler K. , Kispert A.
J. Biol. Chem.282:25748-25759(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TBX18
14.

"PRC2 directly methylates GATA4 and represses its transcriptional activity."
He A. , Shen X. , Ma Q. , Cao J. , von Gise A. , Zhou P. , Wang G. , Marquez V.E. , Orkin S.H. , Pu W.T.
Genes Dev.26:37-42(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION AT LYS-299

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