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Index > Protein center > RAP1GDS1(Gene name) > Human
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  • RAP1GDS1 (Gene name),
  • Rap1 GTPase-GDP dissociation stimulator 1 (Protein name ),  GDS1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    RAP1GDS1;
    Protein name:
    Rap1 GTPase-GDP dissociation stimulator 1;
    Alternative:
    SMG GDS protein;Exchange factor smgGDS;SMG P21 stimulatory GDP/GTP exchange protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    607
    Sequence:
    50:
    MDNLSDTLKK | LKITAVDKTE | DSLEGCLDCL | LQALAQNNTE | TSEKIQASGI | 
    100:
    LQLFASLLTP | QSSCKAKVAN | IIAEVAKNEF | MRIPCVDAGL | ISPLVQLLNS | 
    150:
    KDQEVLLQTG | RALGNICYDS | HEGRSAVDQA | GGAQIVIDHL | RSLCSITDPA | 
    200:
    NEKLLTVFCG | MLMNYSNEND | SLQAQLINMG | VIPTLVKLLG | IHCQNAALTE | 
    250:
    MCLVAFGNLA | ELESSKEQFA | STNIAEELVK | LFKKQIEHDK | REMIFEVLAP | 
    300:
    LAENDAIKLQ | LVEAGLVECL | LEIVQQKVDS | DKEDDITELK | TGSDLMVLLL | 
    350:
    LGDESMQKLF | EGGKGSVFQR | VLSWIPSNNH | QLQLAGALAI | ANFARNDANC | 
    400:
    IHMVDNGIVE | KLMDLLDRHV | EDGNVTVQHA | ALSALRNLAI | PVINKAKMLS | 
    450:
    AGVTEAVLKF | LKSEMPPVQF | KLLGTLRMLI | DAQAEAAEQL | GKNVKLVERL | 
    500:
    VEWCEAKDHA | GVMGESNRLL | SALIRHSKSK | DVIKTIVQSG | GIKHLVTMAT | 
    550:
    SEHVIMQNEA | LVALALIAAL | ELGTAEKDLE | SAKLVQILHR | LLADERSAPE | 
    600:
    IKYNSMVLIC | ALMGSECLHK | EVQDLAFLDV | VSKLRSHENK | SVAQQASLTE | 
    607:
    QRLTVES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    UniGene:
    String:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Rap1 GTPase-GDP dissociation stimulator 1
    Cat.:
    E14245h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Rap1 GTPase-GDP dissociation stimulator 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Rap1 GTPase-GDP dissociation stimulator 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Rap1 GTPase-GDP dissociation stimulator 1
    Cat.:
    U14245h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Rap1 GTPase-GDP dissociation stimulator 1
    Polyclonal Antibody for Human Rap1 GTPase-GDP dissociation stimulator 1
    Monoclonal Antibody for Human Rap1 GTPase-GDP dissociation stimulator 1
    Monoclonal Antibody for Human Rap1 GTPase-GDP dissociation stimulator 1
    Protein for Human Rap1 GTPase-GDP dissociation stimulator 1
    Protein for Human Rap1 GTPase-GDP dissociation stimulator 1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21."
      Kikuchi A. , Kaibuchi K. , Hori Y. , Nonaka H. , Sakoda T. , Kawamura M. , Mizuno T. , Takai Y.
      Oncogene7:289-293(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Brain.
    2. 2.
      "SmgGDS displays differential binding and exchange activity towards different Ras isoforms."
      Vikis H.G. , Stewart S. , Guan K.L.
      Oncogene21:2425-2432(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "The major isoform of RAP1GDS1 mRNA in peripheral blood mononuclear cells encodes an isoform of smgGDS with 12 armadillo repeats."
      Hussey D.J. , Albanese N.O. , Dobrovic A.
      Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Peripheral blood.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3; 4 AND 5);VARIANT THR-56
      tissue: Muscle.
    7. 7.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-230;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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