Protein name:
Gelsolin ;
Alternative:
Brevin ;Actin-depolymerizing factor (ADF) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds to actin and to fibronectin.
Function:
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Subcellular Location:
Isoform 1
Secreted
Protein Attributes:
50:
MAPYRSSLLC | ALLLLALCAL | SPSHAATTSR | GRAQERAPQS | RVSEARPSTM |
100:
VVEHPEFLKA | GKEPGLQIWR | VEKFDLVPVP | PNLYGDFFTG | DAYVILKTVQ |
150:
LRNGNLQYDL | HYWLGNECSQ | DESGAAAIFT | VQLDDYLNGR | AVQHREVQGF |
200:
ESSTFSGYFK | SGLKYKKGGV | ASGFKHVVPN | EVVVQRLFQV | KGRRVVRATE |
250:
VPVSWDSFNN | GDCFILDLGN | NIYQWCGSGS | NKFERLKATQ | VSKGIRDNER |
300:
SGRAQVHVSE | EGGEPEAMLQ | VLGPKPALPE | GTEDTAKEDA | ANRRLAKLYK |
350:
VSNGAGSMSV | SLVADENPFA | QGALRSEDCF | ILDHGRDGKI | FVWKGKQANM |
400:
EERKAALKTA | SDFISKMQYP | RQTQVSVLPE | GGETPLFKQF | FKNWRDPDQT |
450:
DGPGLGYLSS | HIANVERVPF | DAATLHTSTA | MAAQHGMDDD | GTGQKQIWRI |
500:
EGSNKVPVDP | ATYGQFYGGD | SYIILYNYRH | GGRQGQIIYN | WQGAQSTQDE |
550:
VAASAILTAQ | LDEELGGTPV | QSRVVQGKEP | AHLMSLFGGK | PMIIYKGGTS |
600:
RDGGQTAPAS | IRLFQVRASS | SGATRAVEVM | PKSGALNSND | AFVLKTPSAA |
650:
YLWVGAGASE | AEKTGAQELL | KVLRSQHVQV | EEGSEPDAFW | EALGGKTAYR |
700:
TSPRLKDKKM | DAHPPRLFAC | SNRIGRFVIE | EVPGELMQED | LATDDVMLLD |
750:
TWDQVFVWVG | KDSQEEEKTE | ALTSAKRYIE | TDPANRDRRT | PITVVRQGFE |
780:
PPSFVGWFLG | WDDNYWSVDP | LDRALAELAA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Pig
Mouse
Chicken
ELISA Kit for Mouse Gelsolin
ELISA Kit for Mouse Gelsolin
ELISA Kit for Mouse Gelsolin
ELISA Kit for Mouse Gelsolin
ELISA Kit for Mouse Gelsolin
ELISA Kit for Mouse Gelsolin
CLIA Kit for Mouse Gelsolin
CLIA Kit for Mouse Gelsolin
CLIA Kit for Mouse Gelsolin
CLIA Kit for Mouse Gelsolin
CLIA Kit for Mouse Gelsolin
CLIA Kit for Mouse Gelsolin
Polyclonal Antibody for Mouse Gelsolin
Polyclonal Antibody for Mouse Gelsolin
Polyclonal Antibody for Mouse Gelsolin
Polyclonal Antibody for Mouse Gelsolin
Polyclonal Antibody for Mouse Gelsolin
Polyclonal Antibody for Mouse Gelsolin
Monoclonal Antibody for Mouse Gelsolin
Monoclonal Antibody for Mouse Gelsolin
Monoclonal Antibody for Mouse Gelsolin
Monoclonal Antibody for Mouse Gelsolin
Monoclonal Antibody for Mouse Gelsolin
Monoclonal Antibody for Mouse Gelsolin
Protein for Mouse Gelsolin
Protein for Mouse Gelsolin
Protein for Mouse Gelsolin
Protein for Mouse Gelsolin
Protein for Mouse Gelsolin
Protein for Mouse Gelsolin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
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Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6J .
tissue :
Head .
tissue :
Spleen .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Mammary gland .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 50-70 (ISOFORM 2);PROTEIN SEQUENCE OF 74-97; 146-160; 167-186; 254-293; 301-336; 359-366; 372-388; 396-445; 456-479; 529-546; 552-562; 583-621; 625-646; 667-673; 712-736 AND 739-746 (ISOFORMS 1/2);CLEAVAGE OF INITIATOR METHIONINE (ISOFORM 2);ACETYLATION AT MET-1 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Embryonic fibroblast .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 51-73
tissue :
Fibroblast .
6.
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Immunity36:795-806(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH EIF2AK2
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"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
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Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-582;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .