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Index > Protein center > Gsn(Gene name) > Mouse
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  • Gsn (Gene name),
  • Gelsolin (Protein name ),  GELS_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Gsn(Gsb);
    Protein name:
    Gelsolin;
    Alternative:
    Brevin;Actin-depolymerizing factor(ADF);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds to actin and to fibronectin.
    Function:
    Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
    Subcellular Location:
    Isoform 1 Secreted
    Protein Attributes:
    Sequence length:
    780
    Sequence:
    50:
    MAPYRSSLLC | ALLLLALCAL | SPSHAATTSR | GRAQERAPQS | RVSEARPSTM | 
    100:
    VVEHPEFLKA | GKEPGLQIWR | VEKFDLVPVP | PNLYGDFFTG | DAYVILKTVQ | 
    150:
    LRNGNLQYDL | HYWLGNECSQ | DESGAAAIFT | VQLDDYLNGR | AVQHREVQGF | 
    200:
    ESSTFSGYFK | SGLKYKKGGV | ASGFKHVVPN | EVVVQRLFQV | KGRRVVRATE | 
    250:
    VPVSWDSFNN | GDCFILDLGN | NIYQWCGSGS | NKFERLKATQ | VSKGIRDNER | 
    300:
    SGRAQVHVSE | EGGEPEAMLQ | VLGPKPALPE | GTEDTAKEDA | ANRRLAKLYK | 
    350:
    VSNGAGSMSV | SLVADENPFA | QGALRSEDCF | ILDHGRDGKI | FVWKGKQANM | 
    400:
    EERKAALKTA | SDFISKMQYP | RQTQVSVLPE | GGETPLFKQF | FKNWRDPDQT | 
    450:
    DGPGLGYLSS | HIANVERVPF | DAATLHTSTA | MAAQHGMDDD | GTGQKQIWRI | 
    500:
    EGSNKVPVDP | ATYGQFYGGD | SYIILYNYRH | GGRQGQIIYN | WQGAQSTQDE | 
    550:
    VAASAILTAQ | LDEELGGTPV | QSRVVQGKEP | AHLMSLFGGK | PMIIYKGGTS | 
    600:
    RDGGQTAPAS | IRLFQVRASS | SGATRAVEVM | PKSGALNSND | AFVLKTPSAA | 
    650:
    YLWVGAGASE | AEKTGAQELL | KVLRSQHVQV | EEGSEPDAFW | EALGGKTAYR | 
    700:
    TSPRLKDKKM | DAHPPRLFAC | SNRIGRFVIE | EVPGELMQED | LATDDVMLLD | 
    750:
    TWDQVFVWVG | KDSQEEEKTE | ALTSAKRYIE | TDPANRDRRT | PITVVRQGFE | 
    780:
    PPSFVGWFLG | WDDNYWSVDP | LDRALAELAA | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Gelsolin
    Cat.:
    E0372h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Gelsolin
    Cat.:
    E0372b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Gelsolin
    Cat.:
    E0372r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Gelsolin
    Cat.:
    E0372p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Gelsolin
    Cat.:
    E0372m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Gelsolin
    Cat.:
    E0372c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Gelsolin
    Cat.:
    U0372m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Gelsolin
    Cat.:
    U0372c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Gelsolin
    Cat.:
    U0372p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Gelsolin
    Cat.:
    U0372r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Gelsolin
    Cat.:
    U0372b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Gelsolin
    Cat.:
    U0372h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse Gelsolin
    Cat.:
    P0372Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Gelsolin
    Cat.:
    P0372Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Gelsolin
    Polyclonal Antibody for Mouse Gelsolin
    Polyclonal Antibody for Mouse Gelsolin
    Polyclonal Antibody for Mouse Gelsolin
    Cat.:
    P0372Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Gelsolin
    Monoclonal Antibody for Mouse Gelsolin
    Monoclonal Antibody for Mouse Gelsolin
    Monoclonal Antibody for Mouse Gelsolin
    Monoclonal Antibody for Mouse Gelsolin
    Monoclonal Antibody for Mouse Gelsolin
    Protein for Mouse Gelsolin
    Protein for Mouse Gelsolin
    Protein for Mouse Gelsolin
    Cat.:
    R0372h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse Gelsolin
    Protein for Mouse Gelsolin
    Protein for Mouse Gelsolin

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    References
    1. 1.
      "Cloning of murine gelsolin and its regulation during differentiation of embryonal carcinoma cells."
      Dieffenbach C.W. , Sengupta D.N. , Krause D. , Sawzak D. , Silverman R.H.
      J. Biol. Chem.264:13281-13288(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      tissue: Head.
      tissue: Spleen.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Mammary gland.
    4. 4.
      Sumpton D.P. , Sandilands E. , Frame M.C. , Bienvenut W.V.
      Submitted (2008-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 50-70 (ISOFORM 2);PROTEIN SEQUENCE OF 74-97; 146-160; 167-186; 254-293; 301-336; 359-366; 372-388; 396-445; 456-479; 529-546; 552-562; 583-621; 625-646; 667-673; 712-736 AND 739-746 (ISOFORMS 1/2);CLEAVAGE OF INITIATOR METHIONINE (ISOFORM 2);ACETYLATION AT MET-1 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Embryonic fibroblast.
    5. 5.
      "Separation and sequencing of familiar and novel murine proteins using preparative two-dimensional gel electrophoresis."
      Merrick B.A. , Patterson R.M. , Wichter L.L. , He C. , Selkirk J.K.
      Electrophoresis15:735-745(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 51-73
      tissue: Fibroblast.
    6. 6.
      "Regulation of actin dynamics by protein kinase R control of gelsolin enforces basal innate immune defense."
      Irving A.T. , Wang D. , Vasilevski O. , Latchoumanin O. , Kozer N. , Clayton A.H. , Szczepny A. , Morimoto H. , Xu D. , Williams B.R. , Sadler A.J.
      Immunity36:795-806(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EIF2AK2
    7. 7.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-582;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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