GLS ELISA Kit for Human(Homo sapiens) | EIAab.comGLS ELISA Kit for Human(Homo sapiens)

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Index > Protein center > GLS(Gene name) > Human

GLS (Gene name),

Glutaminase kidney isoform, mitochondrial (Protein name ), GLSK_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

GLS(GLS1;KIAA0838);

Protein name:

Glutaminase kidney isoform, mitochondrial(GLS);

Alternative:

L-glutamine amidohydrolase;K-glutaminase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine.

Subcellular Location:

Mitochondrion

Protein Attributes:

Sequence length:

669

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

669:

DSDNGKENQT | VHKNLDGLL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000317379

SMR:

O94925

MIM:

138280

String:

O94925

Pfam:

PF12796

UniGene:

Hs.116448

KEGG:

hsa:2744

Uniprot:

O94925

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ELISA Kit for Human GLS

Cat.:

E15055h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human GLS

MSDS:

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ELISA Kit for Human GLS

MSDS:

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CLIA Kit for Human GLS

MSDS:

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CLIA Kit for Human GLS

MSDS:

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CLIA Kit for Human GLS

Cat.:

U15055h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human GLS

Monoclonal Antibody for Human GLS

Protein for Human GLS

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing."
Elgadi K.M. , Meguid R.A. , Qian M. , Souba W.W. , Abcouwer S.F.
Physiol. Genomics1:51-62(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY;ALTERNATIVE SPLICING
tissue: Placenta.
2.

"Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.5:355-364(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
3.

"Identification and expression of human renal and hepatic glutaminase isoforms."
Chavez R.A. , Wang C. , Cong R. , Hawkinson J.E. , Forsayeth J.R.
Submitted (2000-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
4.

"Isolation, characterization and expression of a human brain mitochondrial glutaminase cDNA."
Holcomb T. , Taylor L. , Trohkimoinen J. , Curthoys N.P.
Brain Res. Mol. Brain Res.76:56-63(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
6.

"Adenoma and carcinoma cell lines derived from colorectal tumours express different isoforms of glutaminase."
Turner A. , McGivan J.D.
Submitted (2000-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 225-466
tissue: Colon carcinoma.
7.

"An unappreciated role for RNA surveillance."
Hillman R.T. , Green R.E. , Brenner S.E.
Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)
8.

"Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels."
Buschdorf J.P. , Li Chew L. , Zhang B. , Cao Q. , Liang F.Y. , Liou Y.C. , Zhou Y.T. , Low B.C.
J. Cell Sci.119:3337-3350(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATCAY;SUBCELLULAR LOCATION
9.

"Relative expression of mRNAs coding for glutaminase isoforms in CNS tissues and CNS tumors."
Szeliga M. , Matyja E. , Obara M. , Grajkowska W. , Czernicki T. , Albrecht J.
Neurochem. Res.33:808-813(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY (ISOFORM 1 AND ISOFORM 3)
10.

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
11.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-311;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Mitochondrial localization and structure-based phosphate activation mechanism of glutaminase C with implications for cancer metabolism."
Cassago A. , Ferreira A.P. , Ferreira I.M. , Fornezari C. , Gomes E.R. , Greene K.S. , Pereira H.M. , Garratt R.C. , Dias S.M. , Ambrosio A.L.
Proc. Natl. Acad. Sci. U.S.A.109:1092-1097(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
14.

"Full-length human glutaminase in complex with an allosteric inhibitor."
DeLaBarre B. , Gross S. , Fang C. , Gao Y. , Jha A. , Jiang F. , Song J.J. , Wei W. , Hurov J.B.
Biochemistry50:10764-10770(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 71-550 (ISOFORM 3) IN COMPLEXES WITH GLUTAMATE AND SYNTHETIC INHIBITOR BPTES;PROTEIN SEQUENCE OF N-TERMINUS;CATALYTIC ACTIVITY;MUTAGENESIS OF PHE-318; PHE-322 AND TYR-394;BIOPHYSICOCHEMICAL PROPERTIES;ENZYME REGULATION;IDENTIFICATION BY MASS SPECTROMETRY;SUBUNIT
15.

"Human glutaminase in complex with L-glutamate."
Structural genomics consortium (SGC)
Submitted (2011-07) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 221-533 IN COMPLEX WITH GLUTAMATE

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