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Index > Protein center > PRKCSH(Gene name) > Human
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  • PRKCSH (Gene name),
  • Glucosidase 2 subunit beta (Protein name ),  GLU2B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PRKCSH(G19P1);
    Protein name:
    Glucosidase 2 subunit beta;
    Alternative:
    Glucosidase II subunit beta;80K-H protein;Protein kinase C substrate 60.1 kDa protein heavy chain(PKCSH);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of a catalytic alpha subunit (GANAB) and a beta subunit (PRKCSH). Binds glycosylated PTPRC.
    Function:
    Regulatory subunit of glucosidase II.
    Subcellular Location:
    Endoplasmic reticulum
    Protein Attributes:
    Sequence length:
    528
    Sequence:
    50:
    MLLPLLLLLP | MCWAVEVKRP | RGVSLTNHHF | YDESKPFTCL | DGSATIPFDQ | 
    100:
    VNDDYCDCKD | GSDEPGTAAC | PNGSFHCTNT | GYKPLYIPSN | RVNDGVCDCC | 
    150:
    DGTDEYNSGV | ICENTCKEKG | RKERESLQQM | AEVTREGFRL | KKILIEDWKK | 
    200:
    AREEKQKKLI | ELQAGKKSLE | DQVEMLRTVK | EEAEKPEREA | KEQHQKLWEE | 
    250:
    QLAAAKAQQE | QELAADAFKE | LDDDMDGTVS | VTELQTHPEL | DTDGDGALSE | 
    300:
    AEAQALLSGD | TQTDATSFYD | RVWAAIRDKY | RSEALPTDLP | APSAPDLTEP | 
    350:
    KEEQPPVPSS | PTEEEEEEEE | EEEEEAEEEE | EEEDSEEAPP | PLSPPQPASP | 
    400:
    AEEDKMPPYD | EQTQAFIDAA | QEARNKFEEA | ERSLKDMEES | IRNLEQEISF | 
    450:
    DFGPNGEFAY | LYSQCYELTT | NEYVYRLCPF | KLVSQKPKLG | GSPTSLGTWG | 
    500:
    SWIGPDHDKF | SAMKYEQGTG | CWQGPNRSTT | VRLLCGKETM | VTSTTEPSRC | 
    528:
    EYLMELMTPA | ACPEPPPEAP | TEDDHDEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    Pfam:
    Pfam:
    MIM:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Glucosidase 2 subunit beta
    Cat.:
    E3190h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Glucosidase 2 subunit beta
    Cat.:
    E3190b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Glucosidase 2 subunit beta
    Cat.:
    E3190m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Glucosidase 2 subunit beta
    Cat.:
    U3190h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Glucosidase 2 subunit beta
    Cat.:
    U3190b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Glucosidase 2 subunit beta
    Cat.:
    U3190m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Glucosidase 2 subunit beta
    Cat.:
    P3190Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Glucosidase 2 subunit beta
    Polyclonal Antibody for Human Glucosidase 2 subunit beta
    Cat.:
    P3190Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Glucosidase 2 subunit beta
    Monoclonal Antibody for Human Glucosidase 2 subunit beta
    Monoclonal Antibody for Human Glucosidase 2 subunit beta
    Protein for Human Glucosidase 2 subunit beta
    Protein for Human Glucosidase 2 subunit beta
    Protein for Human Glucosidase 2 subunit beta

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation of cDNAs encoding a substrate for protein kinase C: nucleotide sequence and chromosomal mapping of the gene for a human 80K protein."
      Sakai K. , Masamichi H. , Minoshima S. , Kudoh J. , Fukuyama R. , Shimizu N.
      Genomics5:309-315(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
    2. 2.
      "A 3-Mb region for the familial hemiplegic migraine locus on 19p13.1-p13.2: exclusion of PRKCSH as a candidate gene."
      Ophoff R.A. , Terwindt G.M. , Vergouwe M.N. , van Eijk R. , Mohrenweiser H. , Litt M. , Hofker M.H. , Haan J. , Ferrari M.D. , Frants R.R.
      Eur. J. Hum. Genet.4:321-328(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo."
      Pelletier M.F. , Marcil A. , Sevigny G. , Jakob C.A. , Tessier D.C. , Chevet E. , Menard R. , Bergeron J.J.M. , Thomas D.Y.
      Glycobiology10:815-827(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH GANAB;SUBCELLULAR LOCATION
      tissue: Lymphocyte.
    4. 4.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 130-528 (ISOFORM 1);VARIANT THR-291
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    6. 6.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 22-528 (ISOFORM 2);VARIANT THR-291
      tissue: Lung.
    8. 8.
      "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
      Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
      Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 15-21
      tissue: Platelet.
    9. 9.
      "Mutations in PRKCSH cause isolated autosomal dominant polycystic liver disease."
      Li A. , Davila S. , Furu L. , Qian Q. , Tian X. , Kamath P.S. , King B.F. , Torres V.E. , Somlo S.
      Am. J. Hum. Genet.72:691-703(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PCLD
    10. 10.
      "Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease."
      Drenth J.P.H. , te Morsche R.H.M. , Smink R. , Bonifacino J.S. , Jansen J.B.M.J.
      Nat. Genet.33:345-347(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PCLD
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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