GNRHR ELISA Kit for Human(Homo sapiens) | EIAab.comGNRHR ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > GNRHR(Gene name) > Human

GNRHR (Gene name),

Gonadotropin-releasing hormone receptor (Protein name ), GNRHR_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

GNRHR(GRHR);

Protein name:

Gonadotropin-releasing hormone receptor(GnRH receptor;GnRH-R);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Function:

Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

328

Sequence:

50:

100:

150:

200:

250:

300:

328:

SDPVNHFFFL | FAFLNPCFDP | LIYGYFSL

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Hs.407587

String:

P30968

MIM:

138850

Pfam:

PF00001

SMR:

P30968

STRING:

9606.ENSP00000226413

KEGG:

hsa:2798

Uniprot:

P30968

FOR

ELISA Kit for Human GnRH receptor

Cat.:

E1672m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human GnRH receptor

Cat.:

E1672r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human GnRH receptor

Cat.:

E1672h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human GnRH receptor

Cat.:

E1672p

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human GnRH receptor

Cat.:

E1672d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human GnRH receptor

Cat.:

E1672b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human GnRH receptor

Cat.:

U1672d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human GnRH receptor

Cat.:

U1672p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human GnRH receptor

Cat.:

U1672h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human GnRH receptor

Cat.:

U1672r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human GnRH receptor

Cat.:

U1672m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human GnRH receptor

Cat.:

U1672b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human GnRH receptor

Cat.:

P1672Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human GnRH receptor

Cat.:

P1672Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human GnRH receptor

Cat.:

P1672Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human GnRH receptor

Protein for Human GnRH receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning, sequencing, and expression of human gonadotropin releasing hormone (GnRH) receptor."
Kakar S.S. , Musgrove L.C. , Devor D.C. , Sellers J.C. , Neill J.D.
Biochem. Biophys. Res. Commun.189:289-295(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Pituitary.
2.

"Cloning and characterization of the human GnRH receptor."
Chi L. , Zhou W. , Prikhozhan A. , Flanagan C.A. , Davidson J.S. , Golembo M. , Illing N. , Millar R.P. , Sealfon S.C.
Mol. Cell. Endocrinol.91:R1-R6(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Pituitary.
3.

"The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary."
Kakar S.S. , Grizzle W.E. , Neill J.D.
Mol. Cell. Endocrinol.106:145-149(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Molecular structure of the human gonadotropin-releasing hormone receptor gene."
Kakar S.S.
Eur. J. Endocrinol.137:183-192(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
5.

"Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor."
Grosse R. , Schoneberg T. , Schultz G. , Gudermann T.
Mol. Endocrinol.11:1305-1318(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Pituitary.
6.

"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Kopatz S.A. , Aronstam R.S. , Sharma S.V.
Submitted (2003-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Testis.
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
8.

"Tissue-specific pattern of variant transcripts of the human gonadotropin-releasing hormone receptor gene."
Kottler M.L. , Bergametti F. , Carre M.C. , Morice S. , Decoret E. , Lagarde J.P. , Starzec A. , Counis R.
Eur. J. Endocrinol.140:561-569(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 247-328 (ISOFORM 1)
9.

"A family with hypogonadotropic hypogonadism and mutations in the gonadotropin-releasing hormone receptor."
de Roux N. , Young J. , Misrahi M. , Genet R. , Chanson P. , Schaison G. , Milgrom E.
N. Engl. J. Med.337:1597-1602(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HH7 ARG-106 AND GLN-262
10.

"Mutations in gonadotropin-releasing hormone receptor gene cause hypogonadotropic hypogonadism."
Layman L.C. , Cohen D.P. , Jin M. , Xie J. , Li Z. , Reindollar R.H. , Bolbolan S. , Bick D.P. , Sherins R.R. , Duck L.W. , Musgrove L.C. , Sellers J.C. , Neill J.D.
Nat. Genet.18:14-15(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HH7 GLN-262 AND CYS-284;CHARACTERIZATION OF VARIANTS HH7 GLN-262 AND CYS-284
11.

"The same molecular defects of the gonadotropin-releasing hormone receptor determine a variable degree of hypogonadism in affected kindred."
de Roux N. , Young J. , Brailly-Tabard S. , Misrahi M. , Milgrom E. , Schaison G.
J. Clin. Endocrinol. Metab.84:567-572(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HH7 ARG-106; ARG-217 AND GLN-262;CHARACTERIZATION OF VARIANTS HH7 ARG-106; ARG-217 AND GLN-262
12.

"Resistance of hypogonadic patients with mutated GnRH receptor genes to pulsatile GnRH administration."
Caron P. , Chauvin S. , Christin-Maitre S. , Bennet A. , Lahlou N. , Counis R. , Bouchard P. , Kottler M.-L.
J. Clin. Endocrinol. Metab.84:990-996(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HH7 ASP-129 AND GLN-262;CHARACTERIZATION OF VARIANT HH7 ASP-129
13.

"Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor."
Pralong F.P. , Gomez F. , Castillo E. , Cotecchia S. , Abuin L. , Aubert M.L. , Portmann L. , Gaillard R.C.
J. Clin. Endocrinol. Metab.84:3811-3816(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HH7 ARG-168;CHARACTERIZATION OF VARIANT HH7 ARG-168
14.

"The fertile eunuch variant of idiopathic hypogonadotropic hypogonadism: spontaneous reversal associated with a homozygous mutation in the gonadotropin-releasing hormone receptor."
Pitteloud N. , Boepple P.A. , DeCruz S. , Valkenburgh S.B. , Crowley W.F. Jr. , Hayes F.J.
J. Clin. Endocrinol. Metab.86:2470-2475(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FEUNS ARG-106
15.

"A novel homozygous mutation in the second transmembrane domain of the gonadotrophin releasing hormone receptor gene."
Soederlund D. , Canto P. , de la Chesnaye E. , Ulloa-Aguirre A. , Mendez J.P.
Clin. Endocrinol. (Oxf.)54:493-498(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HH7 LYS-90
16.

"Two novel mutations in the gonadotropin-releasing hormone receptor gene in Brazilian patients with hypogonadotropic hypogonadism and normal olfaction."
Costa E.M.F. , Bedecarrats G.Y. , Mendonca B.B. , Arnhold I.J.P. , Kaiser U.B. , Latronico A.C.
J. Clin. Endocrinol. Metab.86:2680-2686(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HH7 LYS-10; ARG-106 AND HIS-139;CHARACTERIZATION OF VARIANTS HH7 LYS-10; ARG-106 AND HIS-139
17.

"Molecular basis of hypogonadotropic hypogonadism: restoration of mutant (E(90)K) GnRH receptor function by a deletion at a distant site."
Maya-Nunez G. , Janovick J.A. , Ulloa-Aguirre A. , Soederlund D. , Conn P.M. , Mendez J.P.
J. Clin. Endocrinol. Metab.87:2144-2149(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT HH7 LYS-90
18.

"Mutation Ala(171)Thr stabilizes the gonadotropin-releasing hormone receptor in its inactive conformation, causing familial hypogonadotropic hypogonadism."
Karges B. , Karges W. , Mine M. , Ludwig L. , Kuehne R. , Milgrom E. , de Roux N.
J. Clin. Endocrinol. Metab.88:1873-1879(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HH7 THR-171;CHARACTERIZATION OF VARIANT HH7 THR-171
19.

"Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism."
Miraoui H. , Dwyer A.A. , Sykiotis G.P. , Plummer L. , Chung W. , Feng B. , Beenken A. , Clarke J. , Pers T.H. , Dworzynski P. , Keefe K. , Niedziela M. , Raivio T. , Crowley W.F. Jr. , Seminara S.B. , Quinton R. , Hughes V.A. , Kumanov P. , more...
Am. J. Hum. Genet.92:725-743(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HH7 VAL-83; ARG-106 AND GLN-262

Product Feedback Wall

* Email:
*Comments: